FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2099951690> ?p ?o ?g. }

• W2099951690 endingPage "2561" @default.
• W2099951690 startingPage "2552" @default.
• W2099951690 abstract "Survivors of central nervous system (CNS) tumours are particularly vulnerable to tumour- and treatment-related disability. We present the incidence of specific and overall functional and health-related late effects in a national adult survivor cohort. Diagnostic subgroups at particular risk for persistent sequels are identified. Data collection targeted 708 eligible >18 years old survivors, 708 parent proxies and 1000 general population controls. Functional disability including sensory and cognitive impairment, emotional status and pain was assessed using the Health Utilities Index Mark 2/3 (HUI2/3). Survivors and controls, and diagnostic subgroups were contrasted to identify the general and relative risk for late effects by sub-diagnosis. Survivors had persistent late effects in sensation, mobility, self-care and cognition. Deficits in these domains indicated clinically important disability in overall health, although indices of emotion and pain were unaffected compared to controls. Late effects tended to aggravate with time, and female survivors had poorer health. Oligodendroglioma, mixed/unspecified glioma, intracranial germ cell tumour and medulloblastoma survivors had poorest overall health. Least late effects were found for other specified/unspecified CNS tumours (including meningeoma and nerve sheath tumours), and for astrocytoma. An impact on educational, vocational and family-related outcomes, and higher utilisation of social insurance or government subsidies validated health-related sequelae in adulthood. Comparisons with controls confirm persistent disability in multiple functional domains in adult CNS tumour survivors. The heightened proportion of survivors presenting severe disability is a factor that specifically differentiates survivors from controls, although diagnostic subgroups differ significantly regarding the amount and severity of late effects." @default.
• W2099951690 created "2016-06-24" @default.
• W2099951690 creator A5014035265 @default.
• W2099951690 creator A5024894631 @default.
• W2099951690 creator A5025870036 @default.
• W2099951690 creator A5063428392 @default.
• W2099951690 creator A5080854104 @default.
• W2099951690 date "2009-09-01" @default.
• W2099951690 modified "2023-10-14" @default.
• W2099951690 title "Health and persistent functional late effects in adult survivors of childhood CNS tumours: A population-based cohort study" @default.
• W2099951690 cites W1874530054 @default.
• W2099951690 cites W1886529049 @default.
• W2099951690 cites W1982771906 @default.
• W2099951690 cites W1983992309 @default.
• W2099951690 cites W1997634268 @default.
• W2099951690 cites W2015583354 @default.
• W2099951690 cites W2015758016 @default.
• W2099951690 cites W2023221185 @default.
• W2099951690 cites W2028043264 @default.
• W2099951690 cites W2031087975 @default.
• W2099951690 cites W2032148626 @default.
• W2099951690 cites W2034192179 @default.
• W2099951690 cites W2051883403 @default.
• W2099951690 cites W2052608879 @default.
• W2099951690 cites W2060839966 @default.
• W2099951690 cites W2060886633 @default.
• W2099951690 cites W2070444599 @default.
• W2099951690 cites W2077830503 @default.
• W2099951690 cites W2077956708 @default.
• W2099951690 cites W2080961678 @default.
• W2099951690 cites W2085378460 @default.
• W2099951690 cites W2085797732 @default.
• W2099951690 cites W2113574953 @default.
• W2099951690 cites W2115662243 @default.
• W2099951690 cites W2116638944 @default.
• W2099951690 cites W2126529130 @default.
• W2099951690 cites W2138736208 @default.
• W2099951690 cites W2154916612 @default.
• W2099951690 cites W2164777277 @default.
• W2099951690 cites W2238448948 @default.
• W2099951690 cites W715351 @default.
• W2099951690 doi "https://doi.org/10.1016/j.ejca.2009.06.008" @default.
• W2099951690 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19616428" @default.
• W2099951690 hasPublicationYear "2009" @default.
• W2099951690 type Work @default.
• W2099951690 sameAs 2099951690 @default.
• W2099951690 citedByCount "66" @default.
• W2099951690 countsByYear W20999516902012 @default.
• W2099951690 countsByYear W20999516902013 @default.
• W2099951690 countsByYear W20999516902014 @default.
• W2099951690 countsByYear W20999516902015 @default.
• W2099951690 countsByYear W20999516902016 @default.
• W2099951690 countsByYear W20999516902017 @default.
• W2099951690 countsByYear W20999516902018 @default.
• W2099951690 countsByYear W20999516902019 @default.
• W2099951690 countsByYear W20999516902020 @default.
• W2099951690 countsByYear W20999516902021 @default.
• W2099951690 countsByYear W20999516902022 @default.
• W2099951690 crossrefType "journal-article" @default.
• W2099951690 hasAuthorship W2099951690A5014035265 @default.
• W2099951690 hasAuthorship W2099951690A5024894631 @default.
• W2099951690 hasAuthorship W2099951690A5025870036 @default.
• W2099951690 hasAuthorship W2099951690A5063428392 @default.
• W2099951690 hasAuthorship W2099951690A5080854104 @default.
• W2099951690 hasConcept C120665830 @default.
• W2099951690 hasConcept C121332964 @default.
• W2099951690 hasConcept C126322002 @default.
• W2099951690 hasConcept C187212893 @default.
• W2099951690 hasConcept C201903717 @default.
• W2099951690 hasConcept C2908647359 @default.
• W2099951690 hasConcept C61511704 @default.
• W2099951690 hasConcept C71924100 @default.
• W2099951690 hasConcept C72563966 @default.
• W2099951690 hasConcept C99454951 @default.
• W2099951690 hasConceptScore W2099951690C120665830 @default.
• W2099951690 hasConceptScore W2099951690C121332964 @default.
• W2099951690 hasConceptScore W2099951690C126322002 @default.
• W2099951690 hasConceptScore W2099951690C187212893 @default.
• W2099951690 hasConceptScore W2099951690C201903717 @default.
• W2099951690 hasConceptScore W2099951690C2908647359 @default.
• W2099951690 hasConceptScore W2099951690C61511704 @default.
• W2099951690 hasConceptScore W2099951690C71924100 @default.
• W2099951690 hasConceptScore W2099951690C72563966 @default.
• W2099951690 hasConceptScore W2099951690C99454951 @default.
• W2099951690 hasIssue "14" @default.
• W2099951690 hasLocation W20999516901 @default.
• W2099951690 hasLocation W20999516902 @default.
• W2099951690 hasOpenAccess W2099951690 @default.
• W2099951690 hasPrimaryLocation W20999516901 @default.
• W2099951690 hasRelatedWork W1606496894 @default.
• W2099951690 hasRelatedWork W2019060938 @default.
• W2099951690 hasRelatedWork W2100632149 @default.
• W2099951690 hasRelatedWork W2103425699 @default.
• W2099951690 hasRelatedWork W2148718224 @default.
• W2099951690 hasRelatedWork W2330453918 @default.
• W2099951690 hasRelatedWork W2363171232 @default.
• W2099951690 hasRelatedWork W2805271636 @default.
• W2099951690 hasRelatedWork W3081332639 @default.

• next