FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2099971546> ?p ?o ?g. }

• W2099971546 endingPage "1147" @default.
• W2099971546 startingPage "1139" @default.
• W2099971546 abstract "The three-dimensional structures of the magnesium- and manganese-bound forms of calbindin D9k were determined to 1.6 A and 1.9 A resolution, respectively, using X-ray crystallography. These two structures are nearly identical but deviate significantly from both the calcium bound form and the metal ion-free (apo) form. The largest structural differences are seen in the C-terminal EF-hand, and involve changes in both metal ion coordination and helix packing. The N-terminal calcium binding site is not occupied by any metal ion in the magnesium and manganese structures, and shows little structural deviation from the apo and calcium bound forms. 1H-NMR and UV spectroscopic studies at physiological ion concentrations show that the C-terminal site of the protein is significantly populated by magnesium at resting cell calcium levels, and that there is a negative allosteric interaction between magnesium and calcium binding. Calcium binding was found to occur with positive cooperativity at physiological magnesium concentration." @default.
• W2099971546 created "2016-06-24" @default.
• W2099971546 creator A5029499060 @default.
• W2099971546 creator A5059619902 @default.
• W2099971546 creator A5063171470 @default.
• W2099971546 creator A5070625264 @default.
• W2099971546 creator A5080591106 @default.
• W2099971546 creator A5087153400 @default.
• W2099971546 date "1997-06-01" @default.
• W2099971546 modified "2023-10-15" @default.
• W2099971546 title "Structural basis for the negative allostery between Ca²⁺- and Mg²⁺-binding in the intracellular Ca²⁺-receptor calbindin D_9k" @default.
• W2099971546 cites W1490719314 @default.
• W2099971546 cites W1493544534 @default.
• W2099971546 cites W1511835529 @default.
• W2099971546 cites W1566619188 @default.
• W2099971546 cites W1571243084 @default.
• W2099971546 cites W1586321630 @default.
• W2099971546 cites W1587828336 @default.
• W2099971546 cites W1645871876 @default.
• W2099971546 cites W1788894661 @default.
• W2099971546 cites W1870708516 @default.
• W2099971546 cites W1973294017 @default.
• W2099971546 cites W1973838961 @default.
• W2099971546 cites W1977783896 @default.
• W2099971546 cites W1982762633 @default.
• W2099971546 cites W1986191025 @default.
• W2099971546 cites W1987411651 @default.
• W2099971546 cites W1998813486 @default.
• W2099971546 cites W2000840258 @default.
• W2099971546 cites W2001641653 @default.
• W2099971546 cites W2009037103 @default.
• W2099971546 cites W2010619388 @default.
• W2099971546 cites W2013083986 @default.
• W2099971546 cites W2028231353 @default.
• W2099971546 cites W2033967206 @default.
• W2099971546 cites W2057514708 @default.
• W2099971546 cites W2068334214 @default.
• W2099971546 cites W2080178091 @default.
• W2099971546 cites W2083514508 @default.
• W2099971546 cites W2096716204 @default.
• W2099971546 cites W2097813999 @default.
• W2099971546 cites W2241681832 @default.
• W2099971546 cites W2397781043 @default.
• W2099971546 cites W1966551335 @default.
• W2099971546 doi "https://doi.org/10.1002/pro.5560060602" @default.
• W2099971546 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2143716" @default.
• W2099971546 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9194174" @default.
• W2099971546 hasPublicationYear "1997" @default.
• W2099971546 type Work @default.
• W2099971546 sameAs 2099971546 @default.
• W2099971546 citedByCount "69" @default.
• W2099971546 countsByYear W20999715462012 @default.
• W2099971546 countsByYear W20999715462013 @default.
• W2099971546 countsByYear W20999715462014 @default.
• W2099971546 countsByYear W20999715462015 @default.
• W2099971546 countsByYear W20999715462016 @default.
• W2099971546 countsByYear W20999715462018 @default.
• W2099971546 countsByYear W20999715462019 @default.
• W2099971546 countsByYear W20999715462020 @default.
• W2099971546 countsByYear W20999715462021 @default.
• W2099971546 countsByYear W20999715462022 @default.
• W2099971546 crossrefType "journal-article" @default.
• W2099971546 hasAuthorship W2099971546A5029499060 @default.
• W2099971546 hasAuthorship W2099971546A5059619902 @default.
• W2099971546 hasAuthorship W2099971546A5063171470 @default.
• W2099971546 hasAuthorship W2099971546A5070625264 @default.
• W2099971546 hasAuthorship W2099971546A5080591106 @default.
• W2099971546 hasAuthorship W2099971546A5087153400 @default.
• W2099971546 hasBestOaLocation W20999715461 @default.
• W2099971546 hasConcept C107824862 @default.
• W2099971546 hasConcept C122229402 @default.
• W2099971546 hasConcept C12554922 @default.
• W2099971546 hasConcept C145148216 @default.
• W2099971546 hasConcept C166014724 @default.
• W2099971546 hasConcept C166342909 @default.
• W2099971546 hasConcept C170493617 @default.
• W2099971546 hasConcept C178790620 @default.
• W2099971546 hasConcept C185592680 @default.
• W2099971546 hasConcept C26265296 @default.
• W2099971546 hasConcept C519063684 @default.
• W2099971546 hasConcept C528890316 @default.
• W2099971546 hasConcept C543218039 @default.
• W2099971546 hasConcept C544153396 @default.
• W2099971546 hasConcept C55493867 @default.
• W2099971546 hasConcept C8010536 @default.
• W2099971546 hasConcept C86803240 @default.
• W2099971546 hasConceptScore W2099971546C107824862 @default.
• W2099971546 hasConceptScore W2099971546C122229402 @default.
• W2099971546 hasConceptScore W2099971546C12554922 @default.
• W2099971546 hasConceptScore W2099971546C145148216 @default.
• W2099971546 hasConceptScore W2099971546C166014724 @default.
• W2099971546 hasConceptScore W2099971546C166342909 @default.
• W2099971546 hasConceptScore W2099971546C170493617 @default.
• W2099971546 hasConceptScore W2099971546C178790620 @default.
• W2099971546 hasConceptScore W2099971546C185592680 @default.
• W2099971546 hasConceptScore W2099971546C26265296 @default.
• W2099971546 hasConceptScore W2099971546C519063684 @default.
• W2099971546 hasConceptScore W2099971546C528890316 @default.

• next