Matches in SemOpenAlex for { <https://semopenalex.org/work/W2100020671> ?p ?o ?g. }
- W2100020671 endingPage "623" @default.
- W2100020671 startingPage "611" @default.
- W2100020671 abstract "The promyelocytic leukaemia zinc finger (PLZF) protein belongs to the family of Krüppel‐like zinc finger proteins. It is a transcriptional repressor involved in cell cycle control and has been implicated in limb development, differentiation of myeloid cells, and spermatogenesis. Little is known about the regulation of PLZF expression. In search for mediators of progesterone signalling in the female reproductive tract, we discovered induction of PLZF mRNA in primary cultures of human endometrial stromal cells and myometrial smooth muscle cells (SMC) in response to progesterone. Surprisingly, dexamethasone was a more potent inducer of PLZF expression than progesterone and elicited a sustained up‐regulation of PLZF mRNA levels within 2 h. Immunofluorescence showed localization of PLZF to the nuclei of dexamethasone‐treated SMC. In uterine biopsies, nuclear staining for PLZF was found in myometrial cells and endometrial stromal cells of the secretory phase. The transcriptional start site of the PLZF gene was located to position –5801 in SMC. Transfected promoter constructs containing up to 4.1 kb of 5′‐flanking DNA were not induced by activated glucocorticoid or progesterone receptor. In contrast, co‐transfection of c‐jun and c‐fos expression vectors resulted in stimulation of reporter gene activity, indicating an involvement of AP‐1 transcription factors in PLZF expression." @default.
- W2100020671 created "2016-06-24" @default.
- W2100020671 creator A5010120415 @default.
- W2100020671 creator A5011926030 @default.
- W2100020671 creator A5036928744 @default.
- W2100020671 creator A5045920770 @default.
- W2100020671 creator A5079273940 @default.
- W2100020671 creator A5091306061 @default.
- W2100020671 date "2003-10-01" @default.
- W2100020671 modified "2023-09-27" @default.
- W2100020671 title "Promyelocytic leukaemia zinc finger protein (PLZF) is a glucocorticoid- and progesterone-induced transcription factor in human endometrial stromal cells and myometrial smooth muscle cells" @default.
- W2100020671 cites W1489169196 @default.
- W2100020671 cites W1553544241 @default.
- W2100020671 cites W1573784907 @default.
- W2100020671 cites W1598192021 @default.
- W2100020671 cites W1598886839 @default.
- W2100020671 cites W1691626648 @default.
- W2100020671 cites W1775297890 @default.
- W2100020671 cites W188006079 @default.
- W2100020671 cites W1967963412 @default.
- W2100020671 cites W1980722886 @default.
- W2100020671 cites W1981859725 @default.
- W2100020671 cites W1982049230 @default.
- W2100020671 cites W1984565556 @default.
- W2100020671 cites W1986041519 @default.
- W2100020671 cites W1987358042 @default.
- W2100020671 cites W1994110056 @default.
- W2100020671 cites W1999186716 @default.
- W2100020671 cites W2001974814 @default.
- W2100020671 cites W2005404159 @default.
- W2100020671 cites W2007169317 @default.
- W2100020671 cites W2010510192 @default.
- W2100020671 cites W2010519951 @default.
- W2100020671 cites W2014885676 @default.
- W2100020671 cites W2019951288 @default.
- W2100020671 cites W2028520025 @default.
- W2100020671 cites W2031603823 @default.
- W2100020671 cites W2034099650 @default.
- W2100020671 cites W2038933021 @default.
- W2100020671 cites W2042912958 @default.
- W2100020671 cites W2043550667 @default.
- W2100020671 cites W2047203443 @default.
- W2100020671 cites W2052500168 @default.
- W2100020671 cites W2060567263 @default.
- W2100020671 cites W2068246413 @default.
- W2100020671 cites W2070399290 @default.
- W2100020671 cites W2073698793 @default.
- W2100020671 cites W2073936001 @default.
- W2100020671 cites W2076179697 @default.
- W2100020671 cites W2076609567 @default.
- W2100020671 cites W2078802143 @default.
- W2100020671 cites W2089632683 @default.
- W2100020671 cites W2094838095 @default.
- W2100020671 cites W2095421219 @default.
- W2100020671 cites W2097483036 @default.
- W2100020671 cites W2098039383 @default.
- W2100020671 cites W2100768159 @default.
- W2100020671 cites W2102744337 @default.
- W2100020671 cites W2106004899 @default.
- W2100020671 cites W2106470286 @default.
- W2100020671 cites W2109815943 @default.
- W2100020671 cites W2110887144 @default.
- W2100020671 cites W2121179456 @default.
- W2100020671 cites W2125367143 @default.
- W2100020671 cites W2132045524 @default.
- W2100020671 cites W2135070639 @default.
- W2100020671 cites W2140115103 @default.
- W2100020671 cites W2146621640 @default.
- W2100020671 cites W2149470926 @default.
- W2100020671 cites W2153997727 @default.
- W2100020671 cites W2165730820 @default.
- W2100020671 cites W2166188229 @default.
- W2100020671 cites W2169254454 @default.
- W2100020671 cites W2169457085 @default.
- W2100020671 cites W2213819630 @default.
- W2100020671 cites W2317413050 @default.
- W2100020671 cites W2326476347 @default.
- W2100020671 cites W2436699798 @default.
- W2100020671 cites W308204182 @default.
- W2100020671 cites W3140867441 @default.
- W2100020671 doi "https://doi.org/10.1093/molehr/gag080" @default.
- W2100020671 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12970399" @default.
- W2100020671 hasPublicationYear "2003" @default.
- W2100020671 type Work @default.
- W2100020671 sameAs 2100020671 @default.
- W2100020671 citedByCount "53" @default.
- W2100020671 countsByYear W21000206712012 @default.
- W2100020671 countsByYear W21000206712013 @default.
- W2100020671 countsByYear W21000206712014 @default.
- W2100020671 countsByYear W21000206712015 @default.
- W2100020671 countsByYear W21000206712016 @default.
- W2100020671 countsByYear W21000206712017 @default.
- W2100020671 countsByYear W21000206712018 @default.
- W2100020671 countsByYear W21000206712019 @default.
- W2100020671 countsByYear W21000206712020 @default.
- W2100020671 countsByYear W21000206712021 @default.
- W2100020671 countsByYear W21000206712023 @default.
- W2100020671 crossrefType "journal-article" @default.