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- W2100021832 abstract "Eicosanoids have been implicated in the pathogenesis of autoimmune diseases. In this study, peritoneal macrophages from autoimmune-prone mice were examined for their capacity to produce proinflammatory 5-lipoxygenase metabolites. The results indicate that enhanced production of leukotriene C4 is a common feature of murine autoimmunity and suggest further that aberrations in 5-lipoxygenase activity may play a role in the development of lupus." @default.
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- W2100021832 date "1988-08-01" @default.
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- W2100021832 title "Aberrant production of leukotriene C4 by macrophages from autoimmune-prone mice." @default.
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- W2100021832 doi "https://doi.org/10.1084/jem.168.2.783" @default.
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