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- W2100034190 abstract "Introduction: Atypical antipsychotics like quetiapine, can cause undesirable alterations in lipid profile and hyperglycemia. They are associated with metabolic and cardiovascular related adverse events in pediatric population, especially when multiple antipsychotics or classes of psychotropic medications are co prescribed. Case Report: A 15yearold, overweight, Hispanic male child was referred to the endocrinology clinic by his primary care provider due to high serum cholesterol, triglyceride and glucose levels. Past history was significant for autism, anxiety with depression and attention deficit disorder for which he was getting psychiatric care and was receiving quetiapine 50 mg daily for more than two years. Physical examination was significant for increased adiposity and overweight. Fasting laboratory studies showed elevated cholesterol and triglycerides. In addition to lifestyle modification including diet and exercise, quetiapine was discontinued and replaced by aripiprazole. Repeat testing after four months showed normalized cholesterol and triglyceride levels. Conclusion: The use of atypical antipsychotics prescribed to children and adolescents with neuropsychiatric disorders has been associated with various adverse effects, including significant weight gain. These adverse effects are of particular concern in children and adolescents due to the immediate and long term health risks associated with weight gain, including obesity, diabetes mellitus and hyperlipidemia." @default.
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- W2100034190 date "2013-01-01" @default.
- W2100034190 modified "2023-10-14" @default.
- W2100034190 title "Quetiapine associated dyslipidemia and hyperglycemia in a pediatric overweight patient" @default.
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- W2100034190 doi "https://doi.org/10.5348/ijcri-2013-02-275-cr-9" @default.
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