FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2100037794> ?p ?o ?g. }

• W2100037794 abstract "<h3>Objectives</h3> To describe clinical and immunohistochemical findings in patients with cutaneous Langerhans cell histiocytosis (LCH) beginning in the first 3 months of life and to define predictors of disease evolution. <h3>Design</h3> Observational retrospective survey from July 15, 1989, to April 30, 2007. <h3>Setting</h3> Referral center in pediatric dermatology. <h3>Patients</h3> Thirty-one patients with a diagnosis of cutaneous LCH in the first 3 months of life and no previous visceral LCH. <h3>Main Outcome Measures</h3> Cutaneous lesion characteristics, regulatory T-lymphocyte density, and E-cadherin expression were assessed. Data were compared between the patient groups with self-regressive vs non–self-regressive forms of cutaneous LCH. Pathologic analysis was performed blinded to patient group. <h3>Results</h3> Self-regressive cutaneous LCH was found in 21 patients and non–self-regressive cutaneous LCH in 10 patients. Monolesional forms, necrotic lesions, hypopigmented macules at presentation, and distal topography of limb lesions were seen only in patients with self-regressive cutaneous LCH. Regulatory T-lymphocyte density correlated with interleukin 10 expression in lesions (<i>r</i> = 0.77,<i>P</i> = .003) but was not predictive of disease evolution. E-cadherin expression by Langerhans cells was found in 7 patients with disease limited to the skin whether self-regressive or not. One patient with secondary disseminated disease showed loss of E-cadherin expression in Langerhans cells. <h3>Conclusions</h3> Some morphologic traits of skin lesions can orient the diagnosis to a self-regressive form of cutaneous LCH. Regulatory T-lymphocyte density does not seem to be predictive of disease evolution. E-cadherin expression seems to be an indicator of limited skin disease but not of disease regression. Additional immunohistochemical study is required to confirm these data." @default.
• W2100037794 created "2016-06-24" @default.
• W2100037794 creator A5004073759 @default.
• W2100037794 creator A5019759127 @default.
• W2100037794 creator A5059823170 @default.
• W2100037794 creator A5064465434 @default.
• W2100037794 creator A5077177728 @default.
• W2100037794 creator A5082425768 @default.
• W2100037794 date "2010-02-01" @default.
• W2100037794 modified "2023-09-26" @default.
• W2100037794 title "Neonatal and Early Infantile Cutaneous Langerhans Cell Histiocytosis" @default.
• W2100037794 cites W1562894951 @default.
• W2100037794 cites W1962132325 @default.
• W2100037794 cites W1963970036 @default.
• W2100037794 cites W1966170131 @default.
• W2100037794 cites W1966802692 @default.
• W2100037794 cites W1968565622 @default.
• W2100037794 cites W1971473512 @default.
• W2100037794 cites W1995966445 @default.
• W2100037794 cites W1997422334 @default.
• W2100037794 cites W2003232560 @default.
• W2100037794 cites W2013722018 @default.
• W2100037794 cites W2017157701 @default.
• W2100037794 cites W2022556924 @default.
• W2100037794 cites W2027204483 @default.
• W2100037794 cites W2032566331 @default.
• W2100037794 cites W2036841808 @default.
• W2100037794 cites W2039544155 @default.
• W2100037794 cites W2039860177 @default.
• W2100037794 cites W2041361019 @default.
• W2100037794 cites W2059773598 @default.
• W2100037794 cites W2059867652 @default.
• W2100037794 cites W2071062089 @default.
• W2100037794 cites W2084626806 @default.
• W2100037794 cites W2091364998 @default.
• W2100037794 cites W2094619855 @default.
• W2100037794 cites W2106971183 @default.
• W2100037794 cites W2110172112 @default.
• W2100037794 cites W2112365205 @default.
• W2100037794 cites W2115054041 @default.
• W2100037794 cites W2121543800 @default.
• W2100037794 cites W2129541749 @default.
• W2100037794 cites W2142434331 @default.
• W2100037794 cites W2320574308 @default.
• W2100037794 cites W2325716909 @default.
• W2100037794 cites W70790581 @default.
• W2100037794 doi "https://doi.org/10.1001/archdermatol.2009.360" @default.
• W2100037794 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20157025" @default.
• W2100037794 hasPublicationYear "2010" @default.
• W2100037794 type Work @default.
• W2100037794 sameAs 2100037794 @default.
• W2100037794 citedByCount "68" @default.
• W2100037794 countsByYear W21000377942012 @default.
• W2100037794 countsByYear W21000377942013 @default.
• W2100037794 countsByYear W21000377942014 @default.
• W2100037794 countsByYear W21000377942015 @default.
• W2100037794 countsByYear W21000377942016 @default.
• W2100037794 countsByYear W21000377942017 @default.
• W2100037794 countsByYear W21000377942018 @default.
• W2100037794 countsByYear W21000377942019 @default.
• W2100037794 countsByYear W21000377942020 @default.
• W2100037794 countsByYear W21000377942021 @default.
• W2100037794 countsByYear W21000377942022 @default.
• W2100037794 countsByYear W21000377942023 @default.
• W2100037794 crossrefType "journal-article" @default.
• W2100037794 hasAuthorship W2100037794A5004073759 @default.
• W2100037794 hasAuthorship W2100037794A5019759127 @default.
• W2100037794 hasAuthorship W2100037794A5059823170 @default.
• W2100037794 hasAuthorship W2100037794A5064465434 @default.
• W2100037794 hasAuthorship W2100037794A5077177728 @default.
• W2100037794 hasAuthorship W2100037794A5082425768 @default.
• W2100037794 hasConcept C142724271 @default.
• W2100037794 hasConcept C16005928 @default.
• W2100037794 hasConcept C2777484599 @default.
• W2100037794 hasConcept C2779134260 @default.
• W2100037794 hasConcept C2780174970 @default.
• W2100037794 hasConcept C2781156865 @default.
• W2100037794 hasConcept C71924100 @default.
• W2100037794 hasConceptScore W2100037794C142724271 @default.
• W2100037794 hasConceptScore W2100037794C16005928 @default.
• W2100037794 hasConceptScore W2100037794C2777484599 @default.
• W2100037794 hasConceptScore W2100037794C2779134260 @default.
• W2100037794 hasConceptScore W2100037794C2780174970 @default.
• W2100037794 hasConceptScore W2100037794C2781156865 @default.
• W2100037794 hasConceptScore W2100037794C71924100 @default.
• W2100037794 hasIssue "2" @default.
• W2100037794 hasLocation W21000377941 @default.
• W2100037794 hasLocation W21000377942 @default.
• W2100037794 hasOpenAccess W2100037794 @default.
• W2100037794 hasPrimaryLocation W21000377941 @default.
• W2100037794 hasRelatedWork W1562894951 @default.
• W2100037794 hasRelatedWork W2008723571 @default.
• W2100037794 hasRelatedWork W2009745955 @default.
• W2100037794 hasRelatedWork W2029844864 @default.
• W2100037794 hasRelatedWork W2045451178 @default.
• W2100037794 hasRelatedWork W2078886881 @default.
• W2100037794 hasRelatedWork W2103701567 @default.
• W2100037794 hasRelatedWork W2405948805 @default.
• W2100037794 hasRelatedWork W2559368399 @default.
• W2100037794 hasRelatedWork W3129510299 @default.

• next