Matches in SemOpenAlex for { <https://semopenalex.org/work/W2100039628> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2100039628 abstract "Objective: To study the relationship between Taq1B polymorphism of the cholesteryl ester transfer protein (CETP) gene and lipid profile in the Egyptian population. A base substitution from G (B1) to A (B2) in intron 1 of the gene leads to 1 of 3 variants, B1B1, B1B2, or B2B2, at the Taq1B site (5454G>A) (Mutalyzer 2.0 B-6).Materials and Methods: Lipid profile parameters and CETP Taq1B polymorphisms were studied in 30 patients with primary combined hyperlipidemia and in 28 control subjects. The lipid profile was measured. Polymerase chain reaction (PCR) and restriction fragment length polymorphism (RFLP) were used to study Taq1B polymorphisms.Results: The B2B2 genotype was significantly lower in the patient group (13.3%) than it was in the control group (35.7%). No significant difference was found in allelic distribution between groups.In the patient group, the B2B2 genotype showed a higher serum high-density lipoprotein cholesterol (HDL-C) and lower total cholesterol (TC)/HDL ratio than B1B1 and B1B2. In the control group, triglycerides (TGs), TC/HDL ratio, and low-density lipoprotein (LDL) levels were lower in the B2B2 genotype than other genotypes.Conclusion: There was a suggested association between Taq1B polymorphism of the CETP gene and lipid profile changes, with the B2B2 genotype being protective against hyperlipidemia and atherosclerosis.* CETP : cholesteryl ester transfer protein PCR : polymerase chain reaction RFLP : restriction fragment length polymorphism HDL-C : high-density lipoprotein cholesterol TC : total cholesterol LDL : low-density lipoprotein CHD : coronary heart disease VLDL : very-low-density lipoprotein AST : aspartate transaminase ALT : alanine transaminase TSH : thyroid-stimulating hormone TG : triglyceride dATP : deoxyadenosine triphosphate cDTP : deoxycytidine triphosphate dGTP : deoxyguanosine triphosphate dTTP : deoxythymidine triphosphate ANOVA : analysis of variance CVD : cardiovascular disease" @default.
- W2100039628 created "2016-06-24" @default.
- W2100039628 creator A5015968062 @default.
- W2100039628 creator A5044713861 @default.
- W2100039628 creator A5055976226 @default.
- W2100039628 date "2011-08-01" @default.
- W2100039628 modified "2023-09-26" @default.
- W2100039628 title "Cholesteryl Ester Transfer Protein Taq1B (g.5454G>A) Gene Polymorphism in Primary Combined Hyperlipidemia in the Egyptian Population" @default.
- W2100039628 cites W1976181942 @default.
- W2100039628 cites W1996730785 @default.
- W2100039628 cites W2010181408 @default.
- W2100039628 cites W2017703585 @default.
- W2100039628 cites W2022663923 @default.
- W2100039628 cites W2025090160 @default.
- W2100039628 cites W2050969923 @default.
- W2100039628 cites W2066858926 @default.
- W2100039628 cites W2087403702 @default.
- W2100039628 cites W2102933262 @default.
- W2100039628 cites W2112339822 @default.
- W2100039628 cites W2118094114 @default.
- W2100039628 cites W2123337267 @default.
- W2100039628 cites W2138196076 @default.
- W2100039628 cites W2339428433 @default.
- W2100039628 cites W4246731911 @default.
- W2100039628 doi "https://doi.org/10.1309/lm2h16zdotiyaadm" @default.
- W2100039628 hasPublicationYear "2011" @default.
- W2100039628 type Work @default.
- W2100039628 sameAs 2100039628 @default.
- W2100039628 citedByCount "4" @default.
- W2100039628 countsByYear W21000396282016 @default.
- W2100039628 countsByYear W21000396282017 @default.
- W2100039628 countsByYear W21000396282019 @default.
- W2100039628 crossrefType "journal-article" @default.
- W2100039628 hasAuthorship W2100039628A5015968062 @default.
- W2100039628 hasAuthorship W2100039628A5044713861 @default.
- W2100039628 hasAuthorship W2100039628A5055976226 @default.
- W2100039628 hasBestOaLocation W21000396281 @default.
- W2100039628 hasConcept C104317684 @default.
- W2100039628 hasConcept C126322002 @default.
- W2100039628 hasConcept C134018914 @default.
- W2100039628 hasConcept C135763542 @default.
- W2100039628 hasConcept C149737253 @default.
- W2100039628 hasConcept C168007829 @default.
- W2100039628 hasConcept C185592680 @default.
- W2100039628 hasConcept C2778163477 @default.
- W2100039628 hasConcept C2779091943 @default.
- W2100039628 hasConcept C2780072125 @default.
- W2100039628 hasConcept C2780541478 @default.
- W2100039628 hasConcept C45505151 @default.
- W2100039628 hasConcept C54355233 @default.
- W2100039628 hasConcept C555293320 @default.
- W2100039628 hasConcept C71924100 @default.
- W2100039628 hasConcept C76252995 @default.
- W2100039628 hasConcept C8243546 @default.
- W2100039628 hasConcept C86803240 @default.
- W2100039628 hasConceptScore W2100039628C104317684 @default.
- W2100039628 hasConceptScore W2100039628C126322002 @default.
- W2100039628 hasConceptScore W2100039628C134018914 @default.
- W2100039628 hasConceptScore W2100039628C135763542 @default.
- W2100039628 hasConceptScore W2100039628C149737253 @default.
- W2100039628 hasConceptScore W2100039628C168007829 @default.
- W2100039628 hasConceptScore W2100039628C185592680 @default.
- W2100039628 hasConceptScore W2100039628C2778163477 @default.
- W2100039628 hasConceptScore W2100039628C2779091943 @default.
- W2100039628 hasConceptScore W2100039628C2780072125 @default.
- W2100039628 hasConceptScore W2100039628C2780541478 @default.
- W2100039628 hasConceptScore W2100039628C45505151 @default.
- W2100039628 hasConceptScore W2100039628C54355233 @default.
- W2100039628 hasConceptScore W2100039628C555293320 @default.
- W2100039628 hasConceptScore W2100039628C71924100 @default.
- W2100039628 hasConceptScore W2100039628C76252995 @default.
- W2100039628 hasConceptScore W2100039628C8243546 @default.
- W2100039628 hasConceptScore W2100039628C86803240 @default.
- W2100039628 hasLocation W21000396281 @default.
- W2100039628 hasOpenAccess W2100039628 @default.
- W2100039628 hasPrimaryLocation W21000396281 @default.
- W2100039628 hasRelatedWork W1993474233 @default.
- W2100039628 hasRelatedWork W2001790643 @default.
- W2100039628 hasRelatedWork W2005247682 @default.
- W2100039628 hasRelatedWork W2020499871 @default.
- W2100039628 hasRelatedWork W2061662894 @default.
- W2100039628 hasRelatedWork W2092206145 @default.
- W2100039628 hasRelatedWork W2092884945 @default.
- W2100039628 hasRelatedWork W2100890171 @default.
- W2100039628 hasRelatedWork W2113503721 @default.
- W2100039628 hasRelatedWork W2143136952 @default.
- W2100039628 hasRelatedWork W2348041726 @default.
- W2100039628 hasRelatedWork W2375234862 @default.
- W2100039628 hasRelatedWork W2386075147 @default.
- W2100039628 hasRelatedWork W2412398681 @default.
- W2100039628 hasRelatedWork W2435123233 @default.
- W2100039628 hasRelatedWork W2481727439 @default.
- W2100039628 hasRelatedWork W2508183542 @default.
- W2100039628 hasRelatedWork W2612774063 @default.
- W2100039628 hasRelatedWork W2954500348 @default.
- W2100039628 hasRelatedWork W80093208 @default.
- W2100039628 isParatext "false" @default.
- W2100039628 isRetracted "false" @default.
- W2100039628 magId "2100039628" @default.
- W2100039628 workType "article" @default.