Matches in SemOpenAlex for { <https://semopenalex.org/work/W2100041334> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2100041334 endingPage "93" @default.
- W2100041334 startingPage "87" @default.
- W2100041334 abstract "To further our understanding of microspheres as a drug delivery system, the biliary excretion of covalently linked FITC fluorescence polystyrene microspheres of various diameters was investigated after oral and parenteral administration to male Wistar rats. About 36%, 16% 3% and 1% of the dose was excreted into the bile after parenteral injection of 50 nm, 500 nm, 1 micron and 3 microns diameter microspheres, respectively, over 24 h. In addition, about 30%, 11%, 1%, and 1% of the dose, respectively, was found in the blood at 24 h. After oral administration of 50 nm, 500 nm, and 1 micron microspheres, the recovery was about 18%, 8% and 1% of the dose in the bile and about 9%, 1%, and 0% in the blood, respectively. No 3 microns microspheres were detected in the bile or blood after oral administration. Particles were not detected in the urine of any group tested. Thus, the present study demonstrated that biliary excretion plays an important role in the disposition of microspheres administered by the oral or parenteral routes, and there is a size-related excretion of microspheres into the bile." @default.
- W2100041334 created "2016-06-24" @default.
- W2100041334 creator A5016362603 @default.
- W2100041334 creator A5025011435 @default.
- W2100041334 creator A5035791716 @default.
- W2100041334 creator A5047974429 @default.
- W2100041334 creator A5082694156 @default.
- W2100041334 creator A5091285288 @default.
- W2100041334 date "1996-01-01" @default.
- W2100041334 modified "2023-09-25" @default.
- W2100041334 title "Biliary excretion of polystyrene microspheres with covalently linked FITC fluorescence after oral and parenteral administration to male wistar rats" @default.
- W2100041334 cites W1486814308 @default.
- W2100041334 cites W152943885 @default.
- W2100041334 cites W2002705765 @default.
- W2100041334 cites W2003808648 @default.
- W2100041334 cites W2010662335 @default.
- W2100041334 cites W2015582643 @default.
- W2100041334 cites W2027754353 @default.
- W2100041334 cites W2032379349 @default.
- W2100041334 cites W2035906276 @default.
- W2100041334 cites W2045524726 @default.
- W2100041334 cites W2112460567 @default.
- W2100041334 cites W2119087638 @default.
- W2100041334 cites W2121346848 @default.
- W2100041334 cites W2166528187 @default.
- W2100041334 cites W2313119597 @default.
- W2100041334 cites W2413015309 @default.
- W2100041334 doi "https://doi.org/10.3109/10611869609046266" @default.
- W2100041334 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8894968" @default.
- W2100041334 hasPublicationYear "1996" @default.
- W2100041334 type Work @default.
- W2100041334 sameAs 2100041334 @default.
- W2100041334 citedByCount "40" @default.
- W2100041334 countsByYear W21000413342012 @default.
- W2100041334 countsByYear W21000413342013 @default.
- W2100041334 countsByYear W21000413342015 @default.
- W2100041334 countsByYear W21000413342016 @default.
- W2100041334 countsByYear W21000413342019 @default.
- W2100041334 countsByYear W21000413342021 @default.
- W2100041334 countsByYear W21000413342022 @default.
- W2100041334 countsByYear W21000413342023 @default.
- W2100041334 crossrefType "journal-article" @default.
- W2100041334 hasAuthorship W2100041334A5016362603 @default.
- W2100041334 hasAuthorship W2100041334A5025011435 @default.
- W2100041334 hasAuthorship W2100041334A5035791716 @default.
- W2100041334 hasAuthorship W2100041334A5047974429 @default.
- W2100041334 hasAuthorship W2100041334A5082694156 @default.
- W2100041334 hasAuthorship W2100041334A5091285288 @default.
- W2100041334 hasConcept C10146269 @default.
- W2100041334 hasConcept C126322002 @default.
- W2100041334 hasConcept C127413603 @default.
- W2100041334 hasConcept C185592680 @default.
- W2100041334 hasConcept C189942447 @default.
- W2100041334 hasConcept C2777056448 @default.
- W2100041334 hasConcept C2780026642 @default.
- W2100041334 hasConcept C42360764 @default.
- W2100041334 hasConcept C71924100 @default.
- W2100041334 hasConcept C98274493 @default.
- W2100041334 hasConceptScore W2100041334C10146269 @default.
- W2100041334 hasConceptScore W2100041334C126322002 @default.
- W2100041334 hasConceptScore W2100041334C127413603 @default.
- W2100041334 hasConceptScore W2100041334C185592680 @default.
- W2100041334 hasConceptScore W2100041334C189942447 @default.
- W2100041334 hasConceptScore W2100041334C2777056448 @default.
- W2100041334 hasConceptScore W2100041334C2780026642 @default.
- W2100041334 hasConceptScore W2100041334C42360764 @default.
- W2100041334 hasConceptScore W2100041334C71924100 @default.
- W2100041334 hasConceptScore W2100041334C98274493 @default.
- W2100041334 hasIssue "2" @default.
- W2100041334 hasLocation W21000413341 @default.
- W2100041334 hasLocation W21000413342 @default.
- W2100041334 hasOpenAccess W2100041334 @default.
- W2100041334 hasPrimaryLocation W21000413341 @default.
- W2100041334 hasRelatedWork W2009246547 @default.
- W2100041334 hasRelatedWork W2021491915 @default.
- W2100041334 hasRelatedWork W2056371746 @default.
- W2100041334 hasRelatedWork W2075341902 @default.
- W2100041334 hasRelatedWork W2080922556 @default.
- W2100041334 hasRelatedWork W2317172319 @default.
- W2100041334 hasRelatedWork W2318353920 @default.
- W2100041334 hasRelatedWork W2321583603 @default.
- W2100041334 hasRelatedWork W2396995290 @default.
- W2100041334 hasRelatedWork W4245275933 @default.
- W2100041334 hasVolume "4" @default.
- W2100041334 isParatext "false" @default.
- W2100041334 isRetracted "false" @default.
- W2100041334 magId "2100041334" @default.
- W2100041334 workType "article" @default.