Matches in SemOpenAlex for { <https://semopenalex.org/work/W2100042283> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W2100042283 endingPage "81" @default.
- W2100042283 startingPage "71" @default.
- W2100042283 abstract "For the purpose of clarifying the action of procaine physically or molecularly, the pattern of association or dissociation of the surface-bound Ca++ was isotopically investigated when procaine was applied externally. It was presumed that procaine acted in a cationic form and the results were compatible with an interaction of procaine with anionic sites on the membrane.1) The effect of local anesthetics might not be established through the change in membrane potential level, and external Ca ions had no relation to an interaction between these two parameters. Procaine immobilized 45Cakinetics on the membrane surface. During the time of Ca++ immobilization, exchange diffusion of Na ions was stimulated. The immobilizing action of procaine took place regardless of the presence of external Ca ions.2) Procaine acted probably on a protein portion of the membrane, but it was suggested that for this activity the maintenance of an assembly of membrane lipoprotein was required. It was negligible to consider lipoprotein-calcium-procaine complex formation in the membrane. The anionic sites for procaine may locate in a protein portion but are not identical with the sites proper to Ca ions. Procaine and Ca ions do probably not compete for the same site on the membrane components.3) It is supposed from the results that the selective binding of procaine to lipoprotein, particularly to its protein portion and not to original Ca sites, inhibits secondarily an exchangeability of Ca ions preferentially bound to protein by means of induction in a physical sense." @default.
- W2100042283 created "2016-06-24" @default.
- W2100042283 creator A5008267148 @default.
- W2100042283 date "1971-01-01" @default.
- W2100042283 modified "2023-09-27" @default.
- W2100042283 title "THE MODE OF ACTION OF PROCAINE HYDROCHLORIDE, VIEWED FROM 45Ca ION ASSOCIATION WITH THE MEMBRANE SITES OF THE SARTORIUS MUSCLE FIBRES" @default.
- W2100042283 cites W2003235093 @default.
- W2100042283 cites W2004574122 @default.
- W2100042283 cites W2026362024 @default.
- W2100042283 cites W2031490162 @default.
- W2100042283 cites W2074591412 @default.
- W2100042283 cites W2082364612 @default.
- W2100042283 cites W2087383015 @default.
- W2100042283 cites W2090534711 @default.
- W2100042283 cites W2118355529 @default.
- W2100042283 cites W2122778246 @default.
- W2100042283 cites W2158135640 @default.
- W2100042283 cites W2240012238 @default.
- W2100042283 cites W2279980834 @default.
- W2100042283 doi "https://doi.org/10.2739/kurumemedj.18.71" @default.
- W2100042283 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/5206456" @default.
- W2100042283 hasPublicationYear "1971" @default.
- W2100042283 type Work @default.
- W2100042283 sameAs 2100042283 @default.
- W2100042283 citedByCount "4" @default.
- W2100042283 countsByYear W21000422832021 @default.
- W2100042283 crossrefType "journal-article" @default.
- W2100042283 hasAuthorship W2100042283A5008267148 @default.
- W2100042283 hasBestOaLocation W21000422831 @default.
- W2100042283 hasConcept C12554922 @default.
- W2100042283 hasConcept C145148216 @default.
- W2100042283 hasConcept C178790620 @default.
- W2100042283 hasConcept C185592680 @default.
- W2100042283 hasConcept C2776855439 @default.
- W2100042283 hasConcept C2779828710 @default.
- W2100042283 hasConcept C2909950241 @default.
- W2100042283 hasConcept C41625074 @default.
- W2100042283 hasConcept C55493867 @default.
- W2100042283 hasConcept C86803240 @default.
- W2100042283 hasConcept C98274493 @default.
- W2100042283 hasConceptScore W2100042283C12554922 @default.
- W2100042283 hasConceptScore W2100042283C145148216 @default.
- W2100042283 hasConceptScore W2100042283C178790620 @default.
- W2100042283 hasConceptScore W2100042283C185592680 @default.
- W2100042283 hasConceptScore W2100042283C2776855439 @default.
- W2100042283 hasConceptScore W2100042283C2779828710 @default.
- W2100042283 hasConceptScore W2100042283C2909950241 @default.
- W2100042283 hasConceptScore W2100042283C41625074 @default.
- W2100042283 hasConceptScore W2100042283C55493867 @default.
- W2100042283 hasConceptScore W2100042283C86803240 @default.
- W2100042283 hasConceptScore W2100042283C98274493 @default.
- W2100042283 hasIssue "2" @default.
- W2100042283 hasLocation W21000422831 @default.
- W2100042283 hasLocation W21000422832 @default.
- W2100042283 hasOpenAccess W2100042283 @default.
- W2100042283 hasPrimaryLocation W21000422831 @default.
- W2100042283 hasRelatedWork W2011519725 @default.
- W2100042283 hasRelatedWork W2031916723 @default.
- W2100042283 hasRelatedWork W2070228259 @default.
- W2100042283 hasRelatedWork W2071260303 @default.
- W2100042283 hasRelatedWork W2075308389 @default.
- W2100042283 hasRelatedWork W2100042283 @default.
- W2100042283 hasRelatedWork W2126446192 @default.
- W2100042283 hasRelatedWork W2256909687 @default.
- W2100042283 hasRelatedWork W2396128770 @default.
- W2100042283 hasRelatedWork W2427464027 @default.
- W2100042283 hasVolume "18" @default.
- W2100042283 isParatext "false" @default.
- W2100042283 isRetracted "false" @default.
- W2100042283 magId "2100042283" @default.
- W2100042283 workType "article" @default.