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• W2100042908 abstract "Aim In the present study, we investigated the levels of vaspin in gingival crevicular fluid (GCF) and tear fluid in obese patients with chronic periodontitis (CP), and sought to find an association, if any. Methods Forty patients (20 males and 20 females) with moderate–severe CP were selected based on their clinical parameters of gingival index, probing depth (PD), clinical attachment level (CAL), bleeding on probing, body mass index (BMI), and waist circumference, and divided into four groups (n = 10/group): group 1 (healthy non-obese), group 2 (healthy obese), group 3 (non-obese with CP), and group 4 (obese with CP). GCF and tear fluid vaspin levels were estimated by enzyme-linked immunosorbent assay. Results The mean vaspin concentration both in GCF and tear fluid was greater for group 4 (1.84 ± 0.03) and (1.98 ± 0.08), followed by groups 3 (1.35 ± 0.03 and 1.50 ± 0.06), 2 (0.95 ± 0.26 and 1.27 ± 0.51), and then 1 (0.65 ± 0.02 and 0.75 ± 0.02), respectively. Mean vaspin levels correlated with BMI, CAL, and PD. The association between GCF and tear fluid vaspin concentration was also statistically significant (P < 0.001). Conclusion Vaspin can be a novel biomarker connecting inflammatory marker for the systemic inflammatory response in obesity and CP." @default.
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• W2100042908 date "2015-03-10" @default.
• W2100042908 modified "2023-09-26" @default.
• W2100042908 title "Vaspin: a new adipokine correlating the levels of crevicular fluid and tear fluid in periodontitis and obesity" @default.
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• W2100042908 doi "https://doi.org/10.1111/jicd.12149" @default.
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