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- W2100044713 abstract "To determine if the TEM beta-lactamases of Haemophilus influenzae are TEM-1 or derivatives thereof and associated exclusively with the overlapping Pa/Pb promoters.Single nucleotide specific PCR was used to discriminate the polymorphic nucleotides at positions 32 and 317 of the bla(TEM) genes of a collection of TEM-positive strains.All bla(TEM) genes were found to be bla(TEM-1) or derivatives thereof and none bla(TEM-2). The bla(TEM) genes were associated with the P3 promoter, the Pa/Pb promoters or a novel promoter produced as a result of a 135 bp deletion and a G162T substitution.The genetic features of bla(TEM) genes in H. influenzae are different from those in Enterobacteriaceae and more variable than previously recognized." @default.
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- W2100044713 date "2005-07-08" @default.
- W2100044713 modified "2023-09-23" @default.
- W2100044713 title "Variation in selected regions of blaTEM genes and promoters in Haemophilus influenzae" @default.
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- W2100044713 doi "https://doi.org/10.1093/jac/dki238" @default.
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