FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2100053387> ?p ?o ?g. }

• W2100053387 abstract "Background In epidemiologic studies, obesity has been associated with reduced natriuretic peptide ( NP ) concentrations. Reduced NP production could impair the ability of obese individuals to respond to salt loads, increasing the risk of hypertension and other disorders. We hypothesized that weight loss enhances NP production before and after salt loading. Methods and Results We enrolled 15 obese individuals (mean BMI 45±5.4 kg/m 2 ) undergoing gastric bypass surgery. Before and 6 months after surgery, subjects were admitted to the clinical research center and administered a large‐volume intravenous saline challenge. Echocardiography and serial blood sampling were performed. From the pre‐operative visit to 6 months after surgery, subjects had a mean BMI decrease of 27%. At the 6‐month visit, N‐terminal pro‐atrial NP (Nt‐pro ANP ) levels were 40% higher before, during, and after the saline infusion, compared with levels measured at the same time points during the pre‐operative visit ( P <0.001). The rise in Nt‐pro‐ ANP induced by the saline infusion (≈50%) was similar both before and after surgery (saline, P <0.001; interaction, P =0.2). Similar results were obtained for BNP and Nt‐pro BNP ; resting concentrations increased by 50% and 31%, respectively, after gastric bypass surgery. The increase in NP concentrations after surgery was accompanied by significant decreases in mean arterial pressure ( P =0.004) and heart rate ( P <0.001), and an increase in mitral annular diastolic velocity ( P =0.02). Conclusion In obese individuals, weight loss is associated with a substantial increase in the “setpoint” of circulating NP concentrations. Higher NP concentrations could contribute to an enhanced ability to handle salt loads after weight loss." @default.
• W2100053387 created "2016-06-24" @default.
• W2100053387 creator A5000295012 @default.
• W2100053387 creator A5000746718 @default.
• W2100053387 creator A5006968882 @default.
• W2100053387 creator A5011797463 @default.
• W2100053387 creator A5014193048 @default.
• W2100053387 creator A5014878886 @default.
• W2100053387 creator A5028504642 @default.
• W2100053387 creator A5036896079 @default.
• W2100053387 creator A5041302143 @default.
• W2100053387 creator A5043760436 @default.
• W2100053387 creator A5048111190 @default.
• W2100053387 creator A5060963466 @default.
• W2100053387 creator A5063885457 @default.
• W2100053387 creator A5073142943 @default.
• W2100053387 creator A5074635579 @default.
• W2100053387 creator A5076589229 @default.
• W2100053387 creator A5077949191 @default.
• W2100053387 creator A5079805326 @default.
• W2100053387 creator A5084321828 @default.
• W2100053387 creator A5085451281 @default.
• W2100053387 date "2015-01-05" @default.
• W2100053387 modified "2023-10-03" @default.
• W2100053387 title "Weight Loss, Saline Loading, and the Natriuretic Peptide System" @default.
• W2100053387 cites W1971828803 @default.
• W2100053387 cites W1972695312 @default.
• W2100053387 cites W1989687175 @default.
• W2100053387 cites W1991102782 @default.
• W2100053387 cites W1996886883 @default.
• W2100053387 cites W1999291203 @default.
• W2100053387 cites W2024054722 @default.
• W2100053387 cites W2044885728 @default.
• W2100053387 cites W2049832880 @default.
• W2100053387 cites W2054079313 @default.
• W2100053387 cites W2057501387 @default.
• W2100053387 cites W2080418085 @default.
• W2100053387 cites W2083148009 @default.
• W2100053387 cites W2094289410 @default.
• W2100053387 cites W2097854413 @default.
• W2100053387 cites W2109714035 @default.
• W2100053387 cites W2135305280 @default.
• W2100053387 cites W2149469183 @default.
• W2100053387 cites W2159168356 @default.
• W2100053387 cites W2162422100 @default.
• W2100053387 cites W2235224344 @default.
• W2100053387 cites W2314707437 @default.
• W2100053387 cites W2317730087 @default.
• W2100053387 cites W3022179669 @default.
• W2100053387 cites W4229755335 @default.
• W2100053387 cites W75245760 @default.
• W2100053387 doi "https://doi.org/10.1161/jaha.114.001265" @default.
• W2100053387 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4330054" @default.
• W2100053387 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25595796" @default.
• W2100053387 hasPublicationYear "2015" @default.
• W2100053387 type Work @default.
• W2100053387 sameAs 2100053387 @default.
• W2100053387 citedByCount "34" @default.
• W2100053387 countsByYear W21000533872016 @default.
• W2100053387 countsByYear W21000533872017 @default.
• W2100053387 countsByYear W21000533872018 @default.
• W2100053387 countsByYear W21000533872019 @default.
• W2100053387 countsByYear W21000533872020 @default.
• W2100053387 countsByYear W21000533872021 @default.
• W2100053387 countsByYear W21000533872022 @default.
• W2100053387 countsByYear W21000533872023 @default.
• W2100053387 crossrefType "journal-article" @default.
• W2100053387 hasAuthorship W2100053387A5000295012 @default.
• W2100053387 hasAuthorship W2100053387A5000746718 @default.
• W2100053387 hasAuthorship W2100053387A5006968882 @default.
• W2100053387 hasAuthorship W2100053387A5011797463 @default.
• W2100053387 hasAuthorship W2100053387A5014193048 @default.
• W2100053387 hasAuthorship W2100053387A5014878886 @default.
• W2100053387 hasAuthorship W2100053387A5028504642 @default.
• W2100053387 hasAuthorship W2100053387A5036896079 @default.
• W2100053387 hasAuthorship W2100053387A5041302143 @default.
• W2100053387 hasAuthorship W2100053387A5043760436 @default.
• W2100053387 hasAuthorship W2100053387A5048111190 @default.
• W2100053387 hasAuthorship W2100053387A5060963466 @default.
• W2100053387 hasAuthorship W2100053387A5063885457 @default.
• W2100053387 hasAuthorship W2100053387A5073142943 @default.
• W2100053387 hasAuthorship W2100053387A5074635579 @default.
• W2100053387 hasAuthorship W2100053387A5076589229 @default.
• W2100053387 hasAuthorship W2100053387A5077949191 @default.
• W2100053387 hasAuthorship W2100053387A5079805326 @default.
• W2100053387 hasAuthorship W2100053387A5084321828 @default.
• W2100053387 hasAuthorship W2100053387A5085451281 @default.
• W2100053387 hasBestOaLocation W21000533871 @default.
• W2100053387 hasConcept C126322002 @default.
• W2100053387 hasConcept C134018914 @default.
• W2100053387 hasConcept C141071460 @default.
• W2100053387 hasConcept C164705383 @default.
• W2100053387 hasConcept C2775915353 @default.
• W2100053387 hasConcept C2777397205 @default.
• W2100053387 hasConcept C2778069365 @default.
• W2100053387 hasConcept C2778198053 @default.
• W2100053387 hasConcept C511355011 @default.
• W2100053387 hasConcept C544821477 @default.
• W2100053387 hasConcept C57900726 @default.
• W2100053387 hasConcept C71924100 @default.

• next