FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2100057634> ?p ?o ?g. }

• W2100057634 endingPage "526" @default.
• W2100057634 startingPage "517" @default.
• W2100057634 abstract "We report that isomeric monofucosylhexasaccharides, Galβ1–4GlcNAcβ1–3Galβ1–4GlcNAcβ1–3Galβ1–4(Fucα1–3)GlcNAc, Galβ1–4GlcNAcβ1–3Galβ1–4(Fucα1–3)GlcNAcβ1–3Galβ1–4GlcNAc and Galβ1–4(Fucα1–3)GlcNAcβ1–3Galβ1–4GlcNAcβ1–3Galβ1–4GlcNAc, and bifucosylhexasaccharides Galβ1–4GlcNAcβ1–3Galβ1–4(Fucα1–3)GlcNAcβ1–3Galβ1–4(Fucα1–3)GlcNAc, Galβ1–4(Fucα1–3)GlcNAcβ1–3Galβ1–4GlcNAcβ1–3Galβ1–4(Fucα1–3)GlcNAc and Galβ1–4(Fucα1–3)GlcNAcβ1–3Galβ1–4(Fucα1–3)GlcNAcβ1–3Galβ1–4GlcNAc can be isolated in pure form from reaction mixtures of the linear hexasaccharide Galβ1–4GlcNAcβ1–3Galβ1–4GlcNAcβ1–3Galβ1–4GlcNAc with GDP-fucose and α1,3-fucosyltransferases of human milk. The pure isomers were characterized in several ways; 1H-NMR spectroscopy, for instance, revealed distinct resonances associated with the Lewis x group [Galβ1–4(Fucα1–3)GlcNAc] located at the proximal, middle, and distal positions of the polylactosamine chain. Chromatography on immobilized wheat germ agglutinin was crucial in the separation process used; the isomers carrying the fucose at the reducing end GlcNAc possessed particularly low affinities for the lectin. Isomeric monofucosyl derivatives of the pentasaccharides GlcNAcβ1–3Galβ1–4GlcNAcβ1–3Galβ1–4GlcNAc and Galα1–3Galβ1–4GlcNAcβ1–3Galβ1–4GlcNAc and the tetrasaccharide Galβ1–4GlcNAcβ1–3Galβ1–4GlcNAc were also obtained in pure form, implying that the methods used are widely applicable. The isomeric Lewis x glycans proved to be recognized in highly variable binding modes by polylactosamine-metabolizing enzymes, e.g., the midchain β1,6-GlcNAc transferase (Leppänen et al., Biochemistry, 36, 13729–13735, 1997)." @default.
• W2100057634 created "2016-06-24" @default.
• W2100057634 creator A5003676223 @default.
• W2100057634 creator A5014308196 @default.
• W2100057634 creator A5023405694 @default.
• W2100057634 creator A5051355622 @default.
• W2100057634 creator A5061502860 @default.
• W2100057634 creator A5062460269 @default.
• W2100057634 creator A5073150866 @default.
• W2100057634 creator A5090240897 @default.
• W2100057634 date "1999-05-01" @default.
• W2100057634 modified "2023-10-06" @default.
• W2100057634 title "Isolation and characterization of linear polylactosamines containing one and two site-specifically positioned Lewis x determinants: WGA agarose chromatography in fractionation of mixtures generated by random, partial enzymatic alpha3-fucosylation of pure polylactosamines" @default.
• W2100057634 cites W1273086814 @default.
• W2100057634 cites W1502402568 @default.
• W2100057634 cites W1504350545 @default.
• W2100057634 cites W1516236635 @default.
• W2100057634 cites W1520792625 @default.
• W2100057634 cites W1964568732 @default.
• W2100057634 cites W1965562807 @default.
• W2100057634 cites W1970321841 @default.
• W2100057634 cites W1971723254 @default.
• W2100057634 cites W1974589722 @default.
• W2100057634 cites W1977481441 @default.
• W2100057634 cites W1981039867 @default.
• W2100057634 cites W1982747205 @default.
• W2100057634 cites W1990064359 @default.
• W2100057634 cites W1996231539 @default.
• W2100057634 cites W1998879759 @default.
• W2100057634 cites W1999606594 @default.
• W2100057634 cites W2004986312 @default.
• W2100057634 cites W2009466075 @default.
• W2100057634 cites W2010590847 @default.
• W2100057634 cites W2014956171 @default.
• W2100057634 cites W2015701124 @default.
• W2100057634 cites W2025514530 @default.
• W2100057634 cites W2026380980 @default.
• W2100057634 cites W2028984335 @default.
• W2100057634 cites W2033267585 @default.
• W2100057634 cites W2047848797 @default.
• W2100057634 cites W2048211449 @default.
• W2100057634 cites W2056755246 @default.
• W2100057634 cites W2063408899 @default.
• W2100057634 cites W2064327928 @default.
• W2100057634 cites W2072163165 @default.
• W2100057634 cites W2082125128 @default.
• W2100057634 cites W2082885255 @default.
• W2100057634 cites W2094411667 @default.
• W2100057634 cites W2102589280 @default.
• W2100057634 cites W2129228320 @default.
• W2100057634 cites W2153343589 @default.
• W2100057634 cites W262925134 @default.
• W2100057634 cites W3145390714 @default.
• W2100057634 doi "https://doi.org/10.1093/glycob/9.5.517" @default.
• W2100057634 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10207184" @default.
• W2100057634 hasPublicationYear "1999" @default.
• W2100057634 type Work @default.
• W2100057634 sameAs 2100057634 @default.
• W2100057634 citedByCount "16" @default.
• W2100057634 countsByYear W21000576342016 @default.
• W2100057634 countsByYear W21000576342019 @default.
• W2100057634 crossrefType "journal-article" @default.
• W2100057634 hasAuthorship W2100057634A5003676223 @default.
• W2100057634 hasAuthorship W2100057634A5014308196 @default.
• W2100057634 hasAuthorship W2100057634A5023405694 @default.
• W2100057634 hasAuthorship W2100057634A5051355622 @default.
• W2100057634 hasAuthorship W2100057634A5061502860 @default.
• W2100057634 hasAuthorship W2100057634A5062460269 @default.
• W2100057634 hasAuthorship W2100057634A5073150866 @default.
• W2100057634 hasAuthorship W2100057634A5090240897 @default.
• W2100057634 hasConcept C108625454 @default.
• W2100057634 hasConcept C185592680 @default.
• W2100057634 hasConcept C2776841590 @default.
• W2100057634 hasConcept C2779212266 @default.
• W2100057634 hasConcept C55493867 @default.
• W2100057634 hasConcept C71240020 @default.
• W2100057634 hasConceptScore W2100057634C108625454 @default.
• W2100057634 hasConceptScore W2100057634C185592680 @default.
• W2100057634 hasConceptScore W2100057634C2776841590 @default.
• W2100057634 hasConceptScore W2100057634C2779212266 @default.
• W2100057634 hasConceptScore W2100057634C55493867 @default.
• W2100057634 hasConceptScore W2100057634C71240020 @default.
• W2100057634 hasIssue "5" @default.
• W2100057634 hasLocation W21000576341 @default.
• W2100057634 hasLocation W21000576342 @default.
• W2100057634 hasOpenAccess W2100057634 @default.
• W2100057634 hasPrimaryLocation W21000576341 @default.
• W2100057634 hasRelatedWork W2008557803 @default.
• W2100057634 hasRelatedWork W2008842285 @default.
• W2100057634 hasRelatedWork W2029686515 @default.
• W2100057634 hasRelatedWork W2057570438 @default.
• W2100057634 hasRelatedWork W2066667630 @default.
• W2100057634 hasRelatedWork W2110702808 @default.
• W2100057634 hasRelatedWork W2195231206 @default.
• W2100057634 hasRelatedWork W2775271973 @default.
• W2100057634 hasRelatedWork W3176331455 @default.
• W2100057634 hasRelatedWork W3216067888 @default.
• W2100057634 hasVolume "9" @default.

• next