FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2100057736> ?p ?o ?g. }

• W2100057736 endingPage "63" @default.
• W2100057736 startingPage "354" @default.
• W2100057736 abstract "To estimate the impact of cotrimoxazole prophylaxis on the survival of human immunodeficiency virus (HIV)-positive tuberculosis (TB) patients.A cohort study with a historical comparison group was conducted. End-of-treatment outcomes and 18-month survival were compared between TB patients registered in 1999 and patients registered in 2000 in Karonga District, Malawi. Case ascertainment, treatment and outpatient follow-up were identical in the two years except that in 2000 cotrimoxazole prophylaxis was offered to HIV-positive patients in addition to routine care. The prophylaxis was provided from the time a patient was identified as HIV-positive until 12 months after registration. Analyses were carried out on an intention-to-treat basis for all TB patients, and also separately by HIV status, TB type and certainty of diagnosis.355 and 362 TB patients were registered in 1999 and 2000, respectively; 70% were HIV-positive. The overall case fatality rate fell from 37% to 29%, i.e. for every 12.5 TB patients treated, one death was averted. Case fatality rates were unchanged between the two years in HIV-negative patients, but fell in HIV-positive patients from 43% to 24%. The improved survival became apparent after the first 2 months and was maintained beyond the end of treatment. The improvement was most marked in patients with smear-positive TB and others with confirmed TB diagnoses.Survival of HIV-positive TB patients improved dramatically with the addition of cotrimoxazole prophylaxis to the treatment regimen. The improvement can be attributed to cotrimoxazole because other factors were unchanged and the survival of HIV-negative patients was not improved. Cotrimoxazole prophylaxis should therefore be added to the routine care of HIV-positive TB patients." @default.
• W2100057736 created "2016-06-24" @default.
• W2100057736 creator A5002036971 @default.
• W2100057736 creator A5012009516 @default.
• W2100057736 creator A5018708959 @default.
• W2100057736 creator A5022706050 @default.
• W2100057736 creator A5049409867 @default.
• W2100057736 creator A5051281716 @default.
• W2100057736 creator A5067307694 @default.
• W2100057736 creator A5086741205 @default.
• W2100057736 creator A5090148937 @default.
• W2100057736 date "2004-05-01" @default.
• W2100057736 modified "2023-09-26" @default.
• W2100057736 title "Cotrimoxazole prophylaxis reduces mortality in human immunodeficiency virus-positive tuberculosis patients in Karonga District, Malawi." @default.
• W2100057736 cites W1521444427 @default.
• W2100057736 cites W1709860686 @default.
• W2100057736 cites W1989549652 @default.
• W2100057736 cites W1989599039 @default.
• W2100057736 cites W1994507215 @default.
• W2100057736 cites W2006886378 @default.
• W2100057736 cites W2054219948 @default.
• W2100057736 cites W2055129845 @default.
• W2100057736 cites W2067534856 @default.
• W2100057736 cites W2130060580 @default.
• W2100057736 cites W2131758462 @default.
• W2100057736 cites W2132136467 @default.
• W2100057736 cites W2138500778 @default.
• W2100057736 cites W2159126559 @default.
• W2100057736 cites W2618242172 @default.
• W2100057736 cites W2724686081 @default.
• W2100057736 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2622842" @default.
• W2100057736 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15298226" @default.
• W2100057736 hasPublicationYear "2004" @default.
• W2100057736 type Work @default.
• W2100057736 sameAs 2100057736 @default.
• W2100057736 citedByCount "41" @default.
• W2100057736 countsByYear W21000577362012 @default.
• W2100057736 countsByYear W21000577362013 @default.
• W2100057736 countsByYear W21000577362014 @default.
• W2100057736 countsByYear W21000577362015 @default.
• W2100057736 countsByYear W21000577362016 @default.
• W2100057736 countsByYear W21000577362019 @default.
• W2100057736 crossrefType "journal-article" @default.
• W2100057736 hasAuthorship W2100057736A5002036971 @default.
• W2100057736 hasAuthorship W2100057736A5012009516 @default.
• W2100057736 hasAuthorship W2100057736A5018708959 @default.
• W2100057736 hasAuthorship W2100057736A5022706050 @default.
• W2100057736 hasAuthorship W2100057736A5049409867 @default.
• W2100057736 hasAuthorship W2100057736A5051281716 @default.
• W2100057736 hasAuthorship W2100057736A5067307694 @default.
• W2100057736 hasAuthorship W2100057736A5086741205 @default.
• W2100057736 hasAuthorship W2100057736A5090148937 @default.
• W2100057736 hasConcept C107130276 @default.
• W2100057736 hasConcept C126322002 @default.
• W2100057736 hasConcept C141071460 @default.
• W2100057736 hasConcept C142724271 @default.
• W2100057736 hasConcept C187212893 @default.
• W2100057736 hasConcept C187316915 @default.
• W2100057736 hasConcept C2781069245 @default.
• W2100057736 hasConcept C2781413609 @default.
• W2100057736 hasConcept C71924100 @default.
• W2100057736 hasConcept C72563966 @default.
• W2100057736 hasConceptScore W2100057736C107130276 @default.
• W2100057736 hasConceptScore W2100057736C126322002 @default.
• W2100057736 hasConceptScore W2100057736C141071460 @default.
• W2100057736 hasConceptScore W2100057736C142724271 @default.
• W2100057736 hasConceptScore W2100057736C187212893 @default.
• W2100057736 hasConceptScore W2100057736C187316915 @default.
• W2100057736 hasConceptScore W2100057736C2781069245 @default.
• W2100057736 hasConceptScore W2100057736C2781413609 @default.
• W2100057736 hasConceptScore W2100057736C71924100 @default.
• W2100057736 hasConceptScore W2100057736C72563966 @default.
• W2100057736 hasIssue "5" @default.
• W2100057736 hasLocation W21000577361 @default.
• W2100057736 hasOpenAccess W2100057736 @default.
• W2100057736 hasPrimaryLocation W21000577361 @default.
• W2100057736 hasRelatedWork W116097412 @default.
• W2100057736 hasRelatedWork W1485769 @default.
• W2100057736 hasRelatedWork W167410557 @default.
• W2100057736 hasRelatedWork W1938925620 @default.
• W2100057736 hasRelatedWork W1972305066 @default.
• W2100057736 hasRelatedWork W20182011 @default.
• W2100057736 hasRelatedWork W2041776821 @default.
• W2100057736 hasRelatedWork W2060831367 @default.
• W2100057736 hasRelatedWork W2079716870 @default.
• W2100057736 hasRelatedWork W2090102465 @default.
• W2100057736 hasRelatedWork W2129994024 @default.
• W2100057736 hasRelatedWork W2130060580 @default.
• W2100057736 hasRelatedWork W2132136467 @default.
• W2100057736 hasRelatedWork W2138500778 @default.
• W2100057736 hasRelatedWork W2143166235 @default.
• W2100057736 hasRelatedWork W2144010669 @default.
• W2100057736 hasRelatedWork W2159324987 @default.
• W2100057736 hasRelatedWork W2162881343 @default.
• W2100057736 hasRelatedWork W2733454721 @default.
• W2100057736 hasRelatedWork W96913099 @default.
• W2100057736 hasVolume "82" @default.
• W2100057736 isParatext "false" @default.

• next