FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2100058901> ?p ?o ?g. }

• W2100058901 abstract "For many individuals, daily commuting activities on roadways account for a substantial proportion of total exposure, as well as peak-level exposures, to traffic-related air pollutants (TRAPS) including ultrafine particles, but the health impacts of these exposures are not well-understood. We sought to determine if exposure to TRAPs particles during commuting causes acute oxidative stress in the respiratory tract or changes in heart rate variability (HRV), a measure of autonomic activity. We conducted a randomized, cross-over trial in which twenty-one young adults took two 1.5-hr rides in a passenger vehicle in morning rush-hour traffic. The subjects wore a powered-air-purifying respirator, and were blinded to high-efficiency particulate air (HEPA) filtration during one of the rides. At time points before and after the rides, we measured HRV and markers of oxidative stress in exhaled breath condensate (EBC) including nitrite, the sum of nitrite and nitrate, malondialdehyde, and 8-isoprostane. We used mixed linear models to evaluate the effect of exposure on EBC and HRV outcomes, adjusting for pre-exposure response levels. We used linear models to examine the effects of particle concentrations on EBC outcomes at post-exposure time points. Mean EBC nitrite and the sum of nitrite and nitrate were increased from baseline at immediately post-exposure comparing unfiltered to filtered rides (2.11 μM vs 1.70 μM, p = 0.02 and 19.1 μM vs 10.0 μM, p = 0.02, respectively). Mean EBC malondialdehyde (MDA) concentrations were about 10% greater following the unfiltered vs. filtered exposures, although this result was not statistically significant. We found no significant associations between exposure to traffic particles and HRV outcomes at any of the time points. At immediately post-exposure, an interquartile range increase in particle number concentration was associated with statistically significant increases in nitrite (99.4%, 95% CI 32.1% to 166.7%) and nitrite + nitrate (75.7%, 95% CI 21.5% to 130.0%). Increases in markers of oxidative stress in EBC may represent early biological responses to widespread exposures to TRAPs particles that affect passengers in vehicles on heavily trafficked roadways." @default.
• W2100058901 created "2016-06-24" @default.
• W2100058901 creator A5008632210 @default.
• W2100058901 creator A5012071952 @default.
• W2100058901 creator A5021760409 @default.
• W2100058901 creator A5040922723 @default.
• W2100058901 creator A5058128101 @default.
• W2100058901 creator A5060597607 @default.
• W2100058901 creator A5061321242 @default.
• W2100058901 creator A5067937579 @default.
• W2100058901 creator A5076156386 @default.
• W2100058901 creator A5078139435 @default.
• W2100058901 creator A5090246252 @default.
• W2100058901 creator A5090620449 @default.
• W2100058901 date "2014-11-01" @default.
• W2100058901 modified "2023-10-16" @default.
• W2100058901 title "A controlled trial of acute effects of human exposure to traffic particles on pulmonary oxidative stress and heart rate variability" @default.
• W2100058901 cites W1716576606 @default.
• W2100058901 cites W1895410685 @default.
• W2100058901 cites W1966105985 @default.
• W2100058901 cites W1971380647 @default.
• W2100058901 cites W1973968132 @default.
• W2100058901 cites W1982983380 @default.
• W2100058901 cites W1983519380 @default.
• W2100058901 cites W1999665787 @default.
• W2100058901 cites W2000857634 @default.
• W2100058901 cites W2014632257 @default.
• W2100058901 cites W2022758463 @default.
• W2100058901 cites W2027580901 @default.
• W2100058901 cites W2036412531 @default.
• W2100058901 cites W2039049852 @default.
• W2100058901 cites W2039635825 @default.
• W2100058901 cites W2042157149 @default.
• W2100058901 cites W2048253804 @default.
• W2100058901 cites W2058338344 @default.
• W2100058901 cites W2061997886 @default.
• W2100058901 cites W2063945670 @default.
• W2100058901 cites W2065390203 @default.
• W2100058901 cites W2066088673 @default.
• W2100058901 cites W2066939127 @default.
• W2100058901 cites W2069857233 @default.
• W2100058901 cites W2075381371 @default.
• W2100058901 cites W2097027274 @default.
• W2100058901 cites W2099349383 @default.
• W2100058901 cites W2101836733 @default.
• W2100058901 cites W2104761649 @default.
• W2100058901 cites W2107115075 @default.
• W2100058901 cites W2110684831 @default.
• W2100058901 cites W2111854344 @default.
• W2100058901 cites W2113738790 @default.
• W2100058901 cites W2119073032 @default.
• W2100058901 cites W2119285879 @default.
• W2100058901 cites W2123847800 @default.
• W2100058901 cites W2129620264 @default.
• W2100058901 cites W2131930711 @default.
• W2100058901 cites W2132381469 @default.
• W2100058901 cites W2133137968 @default.
• W2100058901 cites W2137450834 @default.
• W2100058901 cites W2137724443 @default.
• W2100058901 cites W2139712977 @default.
• W2100058901 cites W2142577692 @default.
• W2100058901 cites W2150751323 @default.
• W2100058901 cites W2151309635 @default.
• W2100058901 cites W2160039790 @default.
• W2100058901 cites W2166616596 @default.
• W2100058901 cites W2172227760 @default.
• W2100058901 cites W2329956826 @default.
• W2100058901 doi "https://doi.org/10.1186/s12989-014-0045-5" @default.
• W2100058901 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4236446" @default.
• W2100058901 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25361615" @default.
• W2100058901 hasPublicationYear "2014" @default.
• W2100058901 type Work @default.
• W2100058901 sameAs 2100058901 @default.
• W2100058901 citedByCount "51" @default.
• W2100058901 countsByYear W21000589012015 @default.
• W2100058901 countsByYear W21000589012016 @default.
• W2100058901 countsByYear W21000589012017 @default.
• W2100058901 countsByYear W21000589012018 @default.
• W2100058901 countsByYear W21000589012019 @default.
• W2100058901 countsByYear W21000589012020 @default.
• W2100058901 countsByYear W21000589012021 @default.
• W2100058901 countsByYear W21000589012022 @default.
• W2100058901 countsByYear W21000589012023 @default.
• W2100058901 crossrefType "journal-article" @default.
• W2100058901 hasAuthorship W2100058901A5008632210 @default.
• W2100058901 hasAuthorship W2100058901A5012071952 @default.
• W2100058901 hasAuthorship W2100058901A5021760409 @default.
• W2100058901 hasAuthorship W2100058901A5040922723 @default.
• W2100058901 hasAuthorship W2100058901A5058128101 @default.
• W2100058901 hasAuthorship W2100058901A5060597607 @default.
• W2100058901 hasAuthorship W2100058901A5061321242 @default.
• W2100058901 hasAuthorship W2100058901A5067937579 @default.
• W2100058901 hasAuthorship W2100058901A5076156386 @default.
• W2100058901 hasAuthorship W2100058901A5078139435 @default.
• W2100058901 hasAuthorship W2100058901A5090246252 @default.
• W2100058901 hasAuthorship W2100058901A5090620449 @default.
• W2100058901 hasBestOaLocation W21000589011 @default.
• W2100058901 hasConcept C126322002 @default.
• W2100058901 hasConcept C140793950 @default.
• W2100058901 hasConcept C178790620 @default.

• next