FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2100061076> ?p ?o ?g. }

• W2100061076 abstract "Abstract Background Clinical malaria has proven an elusive burden to enumerate. Many cases go undetected by routine disease recording systems. Epidemiologists have, therefore, frequently defaulted to actively measuring malaria in population cohorts through time. Measuring the clinical incidence of malaria longitudinally is labour-intensive and impossible to undertake universally. There is a need, therefore, to define a relationship between clinical incidence and the easier and more commonly measured index of infection prevalence: the parasite rate. This relationship can help provide an informed basis to define malaria burdens in areas where health statistics are inadequate. Methods Formal literature searches were conducted for Plasmodium falciparum malaria incidence surveys undertaken prospectively through active case detection at least every 14 days. The data were abstracted, standardized and geo-referenced. Incidence surveys were time-space matched with modelled estimates of infection prevalence derived from a larger database of parasite prevalence surveys and modelling procedures developed for a global malaria endemicity map. Several potential relationships between clinical incidence and infection prevalence were then specified in a non-parametric Gaussian process model with minimal, biologically informed, prior constraints. Bayesian inference was then used to choose between the candidate models. Results The suggested relationships with credible intervals are shown for the Africa and a combined America and Central and South East Asia regions. In both regions clinical incidence increased slowly and smoothly as a function of infection prevalence. In Africa, when infection prevalence exceeded 40%, clinical incidence reached a plateau of 500 cases per thousand of the population per annum . In the combined America and Central and South East Asia regions, this plateau was reached at 250 cases per thousand of the population per annum . A temporal volatility model was also incorporated to facilitate a closer description of the variance in the observed data. Conclusion It was possible to model a relationship between clinical incidence and P. falciparum infection prevalence but the best-fit models were very noisy reflecting the large variance within the observed opportunistic data sample. This continuous quantification allows for estimates of the clinical burden of P. falciparum of known confidence from wherever an estimate of P. falciparum prevalence is available." @default.
• W2100061076 created "2016-06-24" @default.
• W2100061076 creator A5014066641 @default.
• W2100061076 creator A5018892795 @default.
• W2100061076 creator A5030120234 @default.
• W2100061076 creator A5031889135 @default.
• W2100061076 creator A5040068106 @default.
• W2100061076 creator A5068496319 @default.
• W2100061076 creator A5088968784 @default.
• W2100061076 date "2009-08-05" @default.
• W2100061076 modified "2023-10-16" @default.
• W2100061076 title "Defining the relationship between Plasmodium falciparum parasite rate and clinical disease: statistical models for disease burden estimation" @default.
• W2100061076 cites W1245938035 @default.
• W2100061076 cites W1527710572 @default.
• W2100061076 cites W1554799332 @default.
• W2100061076 cites W1584480503 @default.
• W2100061076 cites W1971032994 @default.
• W2100061076 cites W1985149691 @default.
• W2100061076 cites W1996558251 @default.
• W2100061076 cites W1998684905 @default.
• W2100061076 cites W1999919705 @default.
• W2100061076 cites W2000697976 @default.
• W2100061076 cites W2010272154 @default.
• W2100061076 cites W2066586311 @default.
• W2100061076 cites W2067428749 @default.
• W2100061076 cites W2070704136 @default.
• W2100061076 cites W2073603528 @default.
• W2100061076 cites W2100964818 @default.
• W2100061076 cites W2113510423 @default.
• W2100061076 cites W2113913859 @default.
• W2100061076 cites W2120463581 @default.
• W2100061076 cites W2130761473 @default.
• W2100061076 cites W2131200762 @default.
• W2100061076 cites W2137896704 @default.
• W2100061076 cites W2143138689 @default.
• W2100061076 cites W2143319864 @default.
• W2100061076 cites W2145808088 @default.
• W2100061076 cites W2148446039 @default.
• W2100061076 cites W2168232794 @default.
• W2100061076 cites W2402596861 @default.
• W2100061076 cites W4232383088 @default.
• W2100061076 cites W4241516881 @default.
• W2100061076 cites W4293244076 @default.
• W2100061076 cites W4299603473 @default.
• W2100061076 cites W70890866 @default.
• W2100061076 doi "https://doi.org/10.1186/1475-2875-8-186" @default.
• W2100061076 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2746234" @default.
• W2100061076 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19656373" @default.
• W2100061076 hasPublicationYear "2009" @default.
• W2100061076 type Work @default.
• W2100061076 sameAs 2100061076 @default.
• W2100061076 citedByCount "39" @default.
• W2100061076 countsByYear W21000610762012 @default.
• W2100061076 countsByYear W21000610762013 @default.
• W2100061076 countsByYear W21000610762014 @default.
• W2100061076 countsByYear W21000610762015 @default.
• W2100061076 countsByYear W21000610762016 @default.
• W2100061076 countsByYear W21000610762017 @default.
• W2100061076 countsByYear W21000610762018 @default.
• W2100061076 countsByYear W21000610762020 @default.
• W2100061076 crossrefType "journal-article" @default.
• W2100061076 hasAuthorship W2100061076A5014066641 @default.
• W2100061076 hasAuthorship W2100061076A5018892795 @default.
• W2100061076 hasAuthorship W2100061076A5030120234 @default.
• W2100061076 hasAuthorship W2100061076A5031889135 @default.
• W2100061076 hasAuthorship W2100061076A5040068106 @default.
• W2100061076 hasAuthorship W2100061076A5068496319 @default.
• W2100061076 hasAuthorship W2100061076A5088968784 @default.
• W2100061076 hasBestOaLocation W21000610761 @default.
• W2100061076 hasConcept C120665830 @default.
• W2100061076 hasConcept C121332964 @default.
• W2100061076 hasConcept C126322002 @default.
• W2100061076 hasConcept C138816342 @default.
• W2100061076 hasConcept C142724271 @default.
• W2100061076 hasConcept C144024400 @default.
• W2100061076 hasConcept C149923435 @default.
• W2100061076 hasConcept C203014093 @default.
• W2100061076 hasConcept C2778048844 @default.
• W2100061076 hasConcept C2778371730 @default.
• W2100061076 hasConcept C2779134260 @default.
• W2100061076 hasConcept C2780664029 @default.
• W2100061076 hasConcept C2908647359 @default.
• W2100061076 hasConcept C61511704 @default.
• W2100061076 hasConcept C71924100 @default.
• W2100061076 hasConcept C99454951 @default.
• W2100061076 hasConceptScore W2100061076C120665830 @default.
• W2100061076 hasConceptScore W2100061076C121332964 @default.
• W2100061076 hasConceptScore W2100061076C126322002 @default.
• W2100061076 hasConceptScore W2100061076C138816342 @default.
• W2100061076 hasConceptScore W2100061076C142724271 @default.
• W2100061076 hasConceptScore W2100061076C144024400 @default.
• W2100061076 hasConceptScore W2100061076C149923435 @default.
• W2100061076 hasConceptScore W2100061076C203014093 @default.
• W2100061076 hasConceptScore W2100061076C2778048844 @default.
• W2100061076 hasConceptScore W2100061076C2778371730 @default.
• W2100061076 hasConceptScore W2100061076C2779134260 @default.
• W2100061076 hasConceptScore W2100061076C2780664029 @default.
• W2100061076 hasConceptScore W2100061076C2908647359 @default.
• W2100061076 hasConceptScore W2100061076C61511704 @default.
• W2100061076 hasConceptScore W2100061076C71924100 @default.

• next