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- W2100067485 abstract "The rates of development of resistance to ceftriaxone, ceftazidime, cefepime, and cefpirome in 10 strains of Enterobacter cloacae were determined by daily transfer for 7 days to fresh medium containing twofold serial dilutions of the antibiotics. Development of resistance to ceftriaxone was the most rapid; this was followed by ceftazidime, cefpirome, and cefepime. Resistant variants selected by ceftriaxone and ceftazidime were cross-resistant and produced very high levels of beta-lactamase. On the other hand, resistant variants selected by cefepime and cefpirome often had moderately high levels of beta-lactamase and diminished levels of the 39- to 40-kDa porin protein." @default.
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- W2100067485 date "1996-05-01" @default.
- W2100067485 modified "2023-09-26" @default.
- W2100067485 title "Differences in the resistant variants of Enterobacter cloacae selected by extended-spectrum cephalosporins" @default.
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- W2100067485 doi "https://doi.org/10.1128/aac.40.5.1289" @default.
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