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- W2100067561 abstract "Summary: A single application of C. albicans on the tongue of streptozotocin treated rats makes it possible to study long-term mycotic lesions of lingual mucosa, such as loss of filiform papillae and parakeratosis. The giant conical papillae region is destroyed and irregular depression of the central portion of the dorsal mucosa appears. The epithelium is irregularly thickened and the derm is diffusely infiltrated by lymphocytes. No dysplastic or neoplastic lesions of the mucosa were observed, even after ten months of infection. Zusammenfassung An Streptozotocin-behandelten Ratten wurde die Zunge mit einer Einmaldosis von C. albicans infiziert und dadurch eine chronische Mykose der Zungenschleimhaut erzeugt. Im Zuge der Infektion verschwinden die fadenförmigen Papillen, hier wird die Zungenschleimhaut parakeratotisch. Die warzenförmigen Papillen werden zerstört, und der hintere Teil des Zungenrückens zeigt Schleimhaut-Einsenkungen. Das Epithel ist unregelmäßig verdickt, und die Derma ist diffus mit Lymphozyten infiltriert. Selbst zehn Monate nach der Infektion werden weder Mißbildungen noch maligne Neoplasien beobachtet." @default.
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- W2100067561 date "2009-04-24" @default.
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- W2100067561 title "Experimental Chronic Lingual Candidosis Induced in Streptozotocin Diabetic Rats" @default.
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- W2100067561 doi "https://doi.org/10.1111/j.1439-0507.1987.tb03965.x" @default.
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