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• W2100069519 abstract "Background: Fructooligosaccharides have been claimed to lower fasting glycemia and serum total cholesterol concentrations, possibly via effects of short-chain fatty acids produced during fermentation. Objective: We studied the effects of fructooligosaccharides on blood glucose, serum lipids, and serum acetate in 20 patients with type 2 diabetes. Design: In a randomized, single-blind, crossover design, patients consumed either glucose as a placebo (4 g/d) or fructooligosaccharides (15 g/d) for 20 d each. Average daily intakes of energy, macronutrients, and dietary fiber were similar with both treatments. Results: Compliance, expressed as the proportion of supplements not returned, was near 100% during both treatments. Fructooligosaccharides did not significantly affect fasting concentrations (mmol/L) of serum total cholesterol (95% CI: −0.07, 0.48), HDL cholesterol (−0.04, 0.04), LDL cholesterol (−0.06, 0.34), serum triacylglycerols (−0.21, 0.44), serum free fatty acids (−0.08, 0.04), serum acetate (−0.01, 0.01), or blood glucose (−0.37, 0.40). Conclusions: We conclude that 20 d of dietary supplementation with fructooligosaccharides had no major effect on blood glucose, serum lipids, or serum acetate in patients with type 2 diabetes. This lack of effect was not due to changes in dietary intake, insufficient statistical power, or noncompliance of the patients." @default.
• W2100069519 created "2016-06-24" @default.
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• W2100069519 date "1999-01-01" @default.
• W2100069519 modified "2023-10-16" @default.
• W2100069519 title "Consumption of fructooligosaccharides does not favorably affect blood glucose and serum lipid concentrations in patients with type 2 diabetes" @default.
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• W2100069519 doi "https://doi.org/10.1093/ajcn/69.1.64" @default.
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