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- W2100070910 abstract "The functional activity of T cell colonies grown from normal murine spleen cells has been examined. Up to 75% of the T cell colonies contain cytotoxic lymphocyte precursors (CLP). One out of three colonies contains CLP, which can respond to a given foreign H-2 haplotype. The CLP from the T cell colonies appear identical to the CLP in lymph node tissues in their degree of cross-reactivity and requirement for accessory cells. The effector cells produced were shown to be T lymphocytes. Karyotypic analysis of the cells in colonies grown from a mixture of T6-marked and normal spleen cells indicated that individual colonies were formed from an initial small aggregate of cells. Radiation survival data indicated that the colony-forming unit contains three or fewer proliferating cells." @default.
- W2100070910 created "2016-06-24" @default.
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- W2100070910 date "1980-02-01" @default.
- W2100070910 modified "2023-10-10" @default.
- W2100070910 title "Characterization of in vitro T lymphocyte colonies from normal mouse spleen cells: colonies containing cytotoxic lymphocyte precursors." @default.
- W2100070910 doi "https://doi.org/10.4049/jimmunol.124.2.696" @default.
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