FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2100079356> ?p ?o ?g. }

• W2100079356 endingPage "136" @default.
• W2100079356 startingPage "128" @default.
• W2100079356 abstract "This prospective multicenter study investigated the association of the course of coagulation abnormalities with initial computed tomography (CT) characteristics and outcome in patients with isolated traumatic brain injury (TBI). Patient demographics, coagulation parameters, CT characteristics, and outcome data of moderate and severe TBI patients without major extracranial injuries were prospectively collected. Coagulopathy was defined as absent, early but temporary, delayed, or early and sustained. Delayed/sustained coagulopathy was associated with a higher incidence of disturbed pupillary responses (40% versus 27%; p<0.001) and higher Traumatic Coma Data Bank (TCDB) CT classification (5 (2-5) versus 2 (1-5); p=0.003) than in patients without or with early, but short-lasting coagulopathy. The initial CT of patients with delayed/sustained coagulopathy more frequently showed intracranial hemorrhage and signs of raised intracranial pressure (ICP) compared to patients with early coagulopathy only. This was paralleled by higher in-hospital mortality rates (51% versus 33%; p<0.05), and poorer 6-month functional outcome in patients with delayed/sustained coagulopathy. The relative risk for in-hospital mortality was particularly related to disturbed pupillary responses (OR 8.19; 95% CI 3.15,21.32; p<0.001), early, short-lasting coagulopathy (OR 6.70; 95% CI 1.74,25.78; p=0.006), or delayed/sustained coagulopathy (OR 5.25; 95% CI 2.06,13.40; p=0.001). Delayed/sustained coagulopathy is more frequently associated with CT abnormalities and unfavorable outcome at 6 months after TBI than early, short-lasting coagulopathy. Our finding that not only the mere presence but also the time course of coagulopathy holds predictive value for patient outcome underlines the importance of systematic hemostatic monitoring over time in TBI." @default.
• W2100079356 created "2016-06-24" @default.
• W2100079356 creator A5007385574 @default.
• W2100079356 creator A5008601270 @default.
• W2100079356 creator A5017060039 @default.
• W2100079356 creator A5018032274 @default.
• W2100079356 creator A5019706329 @default.
• W2100079356 creator A5033111238 @default.
• W2100079356 creator A5034321427 @default.
• W2100079356 creator A5049420090 @default.
• W2100079356 date "2012-01-01" @default.
• W2100079356 modified "2023-10-13" @default.
• W2100079356 title "Multicenter Evaluation of the Course of Coagulopathy in Patients with Isolated Traumatic Brain Injury: Relation to CT Characteristics and Outcome" @default.
• W2100079356 cites W1512668152 @default.
• W2100079356 cites W1594364707 @default.
• W2100079356 cites W1948023428 @default.
• W2100079356 cites W1971410089 @default.
• W2100079356 cites W1972491904 @default.
• W2100079356 cites W1974167583 @default.
• W2100079356 cites W1975824095 @default.
• W2100079356 cites W1979028797 @default.
• W2100079356 cites W1982684770 @default.
• W2100079356 cites W1988015026 @default.
• W2100079356 cites W1996279818 @default.
• W2100079356 cites W1996760171 @default.
• W2100079356 cites W2005599164 @default.
• W2100079356 cites W2024996811 @default.
• W2100079356 cites W2032323143 @default.
• W2100079356 cites W2034656907 @default.
• W2100079356 cites W2053409550 @default.
• W2100079356 cites W2058370142 @default.
• W2100079356 cites W2058563954 @default.
• W2100079356 cites W2070921889 @default.
• W2100079356 cites W2071415780 @default.
• W2100079356 cites W2075638893 @default.
• W2100079356 cites W2086216889 @default.
• W2100079356 cites W2087737475 @default.
• W2100079356 cites W2093291707 @default.
• W2100079356 cites W2093825936 @default.
• W2100079356 cites W2115178076 @default.
• W2100079356 cites W2123578204 @default.
• W2100079356 cites W2143958174 @default.
• W2100079356 cites W2149756819 @default.
• W2100079356 cites W2151320901 @default.
• W2100079356 cites W2159358305 @default.
• W2100079356 cites W2312597082 @default.
• W2100079356 cites W4376595788 @default.
• W2100079356 doi "https://doi.org/10.1089/neu.2011.2044" @default.
• W2100079356 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21939390" @default.
• W2100079356 hasPublicationYear "2012" @default.
• W2100079356 type Work @default.
• W2100079356 sameAs 2100079356 @default.
• W2100079356 citedByCount "44" @default.
• W2100079356 countsByYear W21000793562012 @default.
• W2100079356 countsByYear W21000793562013 @default.
• W2100079356 countsByYear W21000793562014 @default.
• W2100079356 countsByYear W21000793562015 @default.
• W2100079356 countsByYear W21000793562016 @default.
• W2100079356 countsByYear W21000793562017 @default.
• W2100079356 countsByYear W21000793562018 @default.
• W2100079356 countsByYear W21000793562019 @default.
• W2100079356 countsByYear W21000793562020 @default.
• W2100079356 countsByYear W21000793562021 @default.
• W2100079356 countsByYear W21000793562022 @default.
• W2100079356 countsByYear W21000793562023 @default.
• W2100079356 crossrefType "journal-article" @default.
• W2100079356 hasAuthorship W2100079356A5007385574 @default.
• W2100079356 hasAuthorship W2100079356A5008601270 @default.
• W2100079356 hasAuthorship W2100079356A5017060039 @default.
• W2100079356 hasAuthorship W2100079356A5018032274 @default.
• W2100079356 hasAuthorship W2100079356A5019706329 @default.
• W2100079356 hasAuthorship W2100079356A5033111238 @default.
• W2100079356 hasAuthorship W2100079356A5034321427 @default.
• W2100079356 hasAuthorship W2100079356A5049420090 @default.
• W2100079356 hasBestOaLocation W21000793562 @default.
• W2100079356 hasConcept C118552586 @default.
• W2100079356 hasConcept C126322002 @default.
• W2100079356 hasConcept C141071460 @default.
• W2100079356 hasConcept C17624336 @default.
• W2100079356 hasConcept C188816634 @default.
• W2100079356 hasConcept C2779936836 @default.
• W2100079356 hasConcept C2781017439 @default.
• W2100079356 hasConcept C42219234 @default.
• W2100079356 hasConcept C71924100 @default.
• W2100079356 hasConceptScore W2100079356C118552586 @default.
• W2100079356 hasConceptScore W2100079356C126322002 @default.
• W2100079356 hasConceptScore W2100079356C141071460 @default.
• W2100079356 hasConceptScore W2100079356C17624336 @default.
• W2100079356 hasConceptScore W2100079356C188816634 @default.
• W2100079356 hasConceptScore W2100079356C2779936836 @default.
• W2100079356 hasConceptScore W2100079356C2781017439 @default.
• W2100079356 hasConceptScore W2100079356C42219234 @default.
• W2100079356 hasConceptScore W2100079356C71924100 @default.
• W2100079356 hasIssue "1" @default.
• W2100079356 hasLocation W21000793561 @default.
• W2100079356 hasLocation W21000793562 @default.
• W2100079356 hasLocation W21000793563 @default.
• W2100079356 hasLocation W21000793564 @default.

• next