FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2100083473> ?p ?o ?g. }

• W2100083473 endingPage "21" @default.
• W2100083473 startingPage "21" @default.
• W2100083473 abstract "Background: While high-sensitivity C-reactive protein (hsCRP) is an independent predictor of cardiovascular risk, global risk prediction models incorporating hsCRP have not been developed for clinical use. Objective: To develop and compare global cardiovascular risk prediction models with and without hsCRP. Design: Observational cohort study. Setting: U.S. female health professionals. Participants: Initially healthy nondiabetic women age 45 years and older participating in the Women's Health Study and followed an average of 10 years. Measurements: Incident cardiovascular events (myocardial infarction, stroke, coronary revascularization, and cardiovascular death). Results: High-sensitivity CRP made a relative contribution to global risk at least as large as that provided by total, high-density lipoprotein (HDL), and low-density lipoprotein (LDL) cholesterol individually, but less than that provided by age, smoking, and blood pressure. All global measures of fit improved when hsCRP was included, with likelihood-based measures demonstrating strong preference for models that include hsCRP. With use of 10-year risk categories of 0% to less than 5%, 5% to less than 10%, 10% to less than 20%, and 20% or greater, risk prediction was more accurate in models that included hsCRP, particularly for risk between 5% and 20%. Among women initially classified with risks of 5% to less than 10% and 10% to less than 20% according to the Adult Treatment Panel III covariables, 21% and 19%, respectively, were reclassified into more accurate risk categories. Although addition of hsCRP had minimal effect on the c-statistic (a measure of model discrimination) once age, smoking, and blood pressure were accounted for, the effect was nonetheless greater than that of total, LDL, or HDL cholesterol, suggesting that the c-statistic may be insensitive in evaluating risk prediction models. Limitations: Data were available only for women. Conclusions: A global risk prediction model that includes hsCRP improves cardiovascular risk classification in women, particularly among those with a 10-year risk of 5% to 20%. In models that include age, blood pressure, and smoking status, hsCRP improves prediction at least as much as do lipid measures." @default.
• W2100083473 created "2016-06-24" @default.
• W2100083473 creator A5084857746 @default.
• W2100083473 creator A5090744975 @default.
• W2100083473 creator A5091595592 @default.
• W2100083473 date "2006-07-04" @default.
• W2100083473 modified "2023-10-17" @default.
• W2100083473 title "The Effect of Including C-Reactive Protein in Cardiovascular Risk Prediction Models for Women" @default.
• W2100083473 cites W1554944419 @default.
• W2100083473 cites W1580788756 @default.
• W2100083473 cites W1963646420 @default.
• W2100083473 cites W1964100346 @default.
• W2100083473 cites W1976430876 @default.
• W2100083473 cites W1982146393 @default.
• W2100083473 cites W1987709455 @default.
• W2100083473 cites W1995945562 @default.
• W2100083473 cites W2000869225 @default.
• W2100083473 cites W2013976776 @default.
• W2100083473 cites W2014663082 @default.
• W2100083473 cites W2018135697 @default.
• W2100083473 cites W2019358153 @default.
• W2100083473 cites W2027415701 @default.
• W2100083473 cites W2032485049 @default.
• W2100083473 cites W2037195555 @default.
• W2100083473 cites W2040433877 @default.
• W2100083473 cites W2044036686 @default.
• W2100083473 cites W2058709767 @default.
• W2100083473 cites W2063058274 @default.
• W2100083473 cites W2065604182 @default.
• W2100083473 cites W2077959816 @default.
• W2100083473 cites W2085943260 @default.
• W2100083473 cites W2087287221 @default.
• W2100083473 cites W2102899779 @default.
• W2100083473 cites W2106665921 @default.
• W2100083473 cites W2115709314 @default.
• W2100083473 cites W2118154631 @default.
• W2100083473 cites W2118310760 @default.
• W2100083473 cites W2123162799 @default.
• W2100083473 cites W2125663761 @default.
• W2100083473 cites W2129925362 @default.
• W2100083473 cites W2135538639 @default.
• W2100083473 cites W2138597449 @default.
• W2100083473 cites W2139203772 @default.
• W2100083473 cites W2140468511 @default.
• W2100083473 cites W2142179136 @default.
• W2100083473 cites W2146456234 @default.
• W2100083473 cites W2157825442 @default.
• W2100083473 cites W2159966843 @default.
• W2100083473 cites W2163092745 @default.
• W2100083473 cites W2165884492 @default.
• W2100083473 cites W2172522430 @default.
• W2100083473 cites W2316243284 @default.
• W2100083473 cites W2316376271 @default.
• W2100083473 cites W2569568519 @default.
• W2100083473 cites W2995133996 @default.
• W2100083473 doi "https://doi.org/10.7326/0003-4819-145-1-200607040-00128" @default.
• W2100083473 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16818925" @default.
• W2100083473 hasPublicationYear "2006" @default.
• W2100083473 type Work @default.
• W2100083473 sameAs 2100083473 @default.
• W2100083473 citedByCount "475" @default.
• W2100083473 countsByYear W21000834732012 @default.
• W2100083473 countsByYear W21000834732013 @default.
• W2100083473 countsByYear W21000834732014 @default.
• W2100083473 countsByYear W21000834732015 @default.
• W2100083473 countsByYear W21000834732016 @default.
• W2100083473 countsByYear W21000834732017 @default.
• W2100083473 countsByYear W21000834732018 @default.
• W2100083473 countsByYear W21000834732019 @default.
• W2100083473 countsByYear W21000834732020 @default.
• W2100083473 countsByYear W21000834732021 @default.
• W2100083473 countsByYear W21000834732022 @default.
• W2100083473 countsByYear W21000834732023 @default.
• W2100083473 crossrefType "journal-article" @default.
• W2100083473 hasAuthorship W2100083473A5084857746 @default.
• W2100083473 hasAuthorship W2100083473A5090744975 @default.
• W2100083473 hasAuthorship W2100083473A5091595592 @default.
• W2100083473 hasConcept C11783203 @default.
• W2100083473 hasConcept C12174686 @default.
• W2100083473 hasConcept C126322002 @default.
• W2100083473 hasConcept C127413603 @default.
• W2100083473 hasConcept C164705383 @default.
• W2100083473 hasConcept C1862650 @default.
• W2100083473 hasConcept C201903717 @default.
• W2100083473 hasConcept C23131810 @default.
• W2100083473 hasConcept C2776914184 @default.
• W2100083473 hasConcept C2779134260 @default.
• W2100083473 hasConcept C2780645631 @default.
• W2100083473 hasConcept C2781195455 @default.
• W2100083473 hasConcept C38652104 @default.
• W2100083473 hasConcept C41008148 @default.
• W2100083473 hasConcept C500558357 @default.
• W2100083473 hasConcept C50440223 @default.
• W2100083473 hasConcept C71924100 @default.
• W2100083473 hasConcept C78519656 @default.
• W2100083473 hasConcept C84393581 @default.
• W2100083473 hasConceptScore W2100083473C11783203 @default.
• W2100083473 hasConceptScore W2100083473C12174686 @default.

• next