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• W2100083844 abstract "To examine whether disrupted regulation of REM sleep propensity is implicated in nightmare (NM) pathophysiology.Heightened REM propensity induced by REM sleep deprivation is belied by increases in REM %, REM density and the dream-like quality of dream mentation during post-deprivation recovery sleep. Compromised regulation of REM sleep propensity may be a contributing factor in the pathophysiology of frequent NMs.A preliminary study of 14 subjects with frequent NMs (> or = 1 NM/week; 27.6+/-9.9 years) and 11 healthy control subjects (<1 NM/month; 24.3+/-5.3 years) was undertaken. Subjects completed home sleep/dream logs and underwent three nights of polysomnographic recording with REM sleep deprivation on night 2. Group differences were assessed for a battery of REM sleep and dream measures on nights 1 and 3.Several measures, including #skipped early-night REM periods, REM latency, REM/NREM cycle length, early/late REM density, REM rebound, late-night REM% and dream vividness, suggested that REM sleep propensity was abnormally low for the frequent NM group throughout the 3-day study.Findings raise the possibility that REM anomalies recorded from NM sufferers sleeping in the laboratory environment reflect a disruption of one or more endogenous regulators of REM sleep propensity." @default.
• W2100083844 created "2016-06-24" @default.
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• W2100083844 date "2010-02-01" @default.
• W2100083844 modified "2023-10-18" @default.
• W2100083844 title "REM sleep characteristics of nightmare sufferers before and after REM sleep deprivation" @default.
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• W2100083844 doi "https://doi.org/10.1016/j.sleep.2008.12.018" @default.
• W2100083844 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20005773" @default.
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