FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2100086068> ?p ?o ?g. }

• W2100086068 endingPage "21" @default.
• W2100086068 startingPage "16" @default.
• W2100086068 abstract "OBJECTIVE This study investigated the relationship between GAD autoantibody (GADA) titers and changing of β-cell function in patients with latent autoimmune diabetes in adults (LADA). RESEARCH DESIGN AND METHODS This 3-year prospective study enrolled 95 subjects from 15 Chinese cities including 25 high-titer (GADA ≥180 units/mL) LADA patients, 42 low-titer (GADA &lt;180 units/mL) LADA patients, and 28 type 2 diabetic patients, the latter two groups as controls of similar age, sex, and BMI. Clinical characteristics were determined annually, including glycosylated hemoglobin (HbA1c), fasting C-peptide (FCP), and 2-h postprandial C-peptide (PCP). RESULTS Despite similar initial FCP and PCP, FCP and PCP both decreased more in subjects with high GADA titer (FCP from mean 0.49 nmol/L at entry to 0.13 nmol/L at the third year; P &lt; 0.05) than with low GADA titer (FCP from mean 0.48 to 0.38 nmol/L) and type 2 diabetes (FCP from mean 0.47 to 0.36 nmol/L); the latter two groups being similar. After 3 years, residual β-cell function (FCP &gt;0.2 nmol/L) was detected in only 42% with an initial high GADA titer compared with 90% with a low GADA titer and 97% with type 2 diabetes (P &lt; 0.01 for both). GADA positivity at the third year persisted more in subjects with initially high GADA (92%) than with low GADA (26%) titers (P &lt; 0.01). CONCLUSIONS In selected LADA patients, initial GADA titers identified subjects with different degrees of persistent autoimmunity and disease progression. LADA patients with a low GADA titer had metabolic phenotypes and loss of β-cell function similar to type 2 diabetic patients." @default.
• W2100086068 created "2016-06-24" @default.
• W2100086068 creator A5011433394 @default.
• W2100086068 creator A5020389679 @default.
• W2100086068 creator A5023110820 @default.
• W2100086068 creator A5027317207 @default.
• W2100086068 creator A5039395009 @default.
• W2100086068 creator A5047326751 @default.
• W2100086068 creator A5058514032 @default.
• W2100086068 creator A5072196735 @default.
• W2100086068 creator A5074081228 @default.
• W2100086068 creator A5076079188 @default.
• W2100086068 creator A5079650987 @default.
• W2100086068 creator A5079738340 @default.
• W2100086068 creator A5081018103 @default.
• W2100086068 creator A5083822183 @default.
• W2100086068 creator A5085352453 @default.
• W2100086068 date "2014-10-21" @default.
• W2100086068 modified "2023-10-03" @default.
• W2100086068 title "Latent Autoimmune Diabetes in Adults With Low-Titer GAD Antibodies: Similar Disease Progression With Type 2 Diabetes" @default.
• W2100086068 cites W1926395376 @default.
• W2100086068 cites W1967314259 @default.
• W2100086068 cites W1969080742 @default.
• W2100086068 cites W1972182005 @default.
• W2100086068 cites W1973877349 @default.
• W2100086068 cites W1978180139 @default.
• W2100086068 cites W1991909333 @default.
• W2100086068 cites W1992251328 @default.
• W2100086068 cites W2001831366 @default.
• W2100086068 cites W2003441653 @default.
• W2100086068 cites W2005722181 @default.
• W2100086068 cites W2042485158 @default.
• W2100086068 cites W2044234363 @default.
• W2100086068 cites W2052669556 @default.
• W2100086068 cites W2064452831 @default.
• W2100086068 cites W2071666133 @default.
• W2100086068 cites W2079120113 @default.
• W2100086068 cites W2098739800 @default.
• W2100086068 cites W2099818969 @default.
• W2100086068 cites W2111497885 @default.
• W2100086068 cites W2116469830 @default.
• W2100086068 cites W2118174270 @default.
• W2100086068 cites W2119560858 @default.
• W2100086068 cites W2124620553 @default.
• W2100086068 cites W2127112142 @default.
• W2100086068 cites W2138534354 @default.
• W2100086068 cites W2138663588 @default.
• W2100086068 cites W2141240964 @default.
• W2100086068 cites W2147139493 @default.
• W2100086068 cites W2150367899 @default.
• W2100086068 cites W2153261516 @default.
• W2100086068 cites W2157775814 @default.
• W2100086068 cites W4234917751 @default.
• W2100086068 doi "https://doi.org/10.2337/dc14-1770" @default.
• W2100086068 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25336751" @default.
• W2100086068 hasPublicationYear "2014" @default.
• W2100086068 type Work @default.
• W2100086068 sameAs 2100086068 @default.
• W2100086068 citedByCount "69" @default.
• W2100086068 countsByYear W21000860682015 @default.
• W2100086068 countsByYear W21000860682016 @default.
• W2100086068 countsByYear W21000860682017 @default.
• W2100086068 countsByYear W21000860682018 @default.
• W2100086068 countsByYear W21000860682019 @default.
• W2100086068 countsByYear W21000860682020 @default.
• W2100086068 countsByYear W21000860682021 @default.
• W2100086068 countsByYear W21000860682022 @default.
• W2100086068 countsByYear W21000860682023 @default.
• W2100086068 crossrefType "journal-article" @default.
• W2100086068 hasAuthorship W2100086068A5011433394 @default.
• W2100086068 hasAuthorship W2100086068A5020389679 @default.
• W2100086068 hasAuthorship W2100086068A5023110820 @default.
• W2100086068 hasAuthorship W2100086068A5027317207 @default.
• W2100086068 hasAuthorship W2100086068A5039395009 @default.
• W2100086068 hasAuthorship W2100086068A5047326751 @default.
• W2100086068 hasAuthorship W2100086068A5058514032 @default.
• W2100086068 hasAuthorship W2100086068A5072196735 @default.
• W2100086068 hasAuthorship W2100086068A5074081228 @default.
• W2100086068 hasAuthorship W2100086068A5076079188 @default.
• W2100086068 hasAuthorship W2100086068A5079650987 @default.
• W2100086068 hasAuthorship W2100086068A5079738340 @default.
• W2100086068 hasAuthorship W2100086068A5081018103 @default.
• W2100086068 hasAuthorship W2100086068A5083822183 @default.
• W2100086068 hasAuthorship W2100086068A5085352453 @default.
• W2100086068 hasBestOaLocation W21000860681 @default.
• W2100086068 hasConcept C126322002 @default.
• W2100086068 hasConcept C134018914 @default.
• W2100086068 hasConcept C159654299 @default.
• W2100086068 hasConcept C163764329 @default.
• W2100086068 hasConcept C203014093 @default.
• W2100086068 hasConcept C22889606 @default.
• W2100086068 hasConcept C2777180221 @default.
• W2100086068 hasConcept C2778199505 @default.
• W2100086068 hasConcept C2781232474 @default.
• W2100086068 hasConcept C32611913 @default.
• W2100086068 hasConcept C555293320 @default.
• W2100086068 hasConcept C71924100 @default.
• W2100086068 hasConcept C90924648 @default.

• next