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- W2100089570 abstract "Abstract1. The metabolism of desmethylchlorimipramine (I) has been investigated in vitro using fortified 9000 g liver homogenates of male rabbits.2. Four metabolic products: N-hydroxydesmethylchlorimipramine (II), 3-(3-chloro-10, 11-dihydro-5H-dibenz[b, f]azepin-5-yl)propanoic acid (III), 10/11-hydroxydesmethyl-chlorimipramine (IV) and 2/8-hydroxydesmethylchlorimipramine (V) were isolated and identified by electron-impact mass spectrometry and n.m.r. spectroscopy.3. Desmethylchlorimipramine (I) undergoes both N- and α-carbon oxidation in addition to aromatic and alicyclic carbon oxidation." @default.
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- W2100089570 date "1982-01-01" @default.
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- W2100089570 title "Metabolic oxidation of desmethylchlorimipraminein vitroby 9000grabbit-liver preparations" @default.
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- W2100089570 doi "https://doi.org/10.3109/00498258209042043" @default.
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