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• W2100091027 abstract "We report the synthesis and in vitro activity of a series of novel pyrrolidinyl pyridones and pyrazinones as potent inhibitors of prolyl oligopeptidase (POP). Within this series, compound 39 was co-crystallized within the catalytic site of a human chimeric POP protein which provided a more detailed understanding of how these inhibitors interacted with the key residues within the catalytic pocket." @default.
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• W2100091027 date "2008-08-01" @default.
• W2100091027 modified "2023-10-01" @default.
• W2100091027 title "Pyrrolidinyl pyridone and pyrazinone analogues as potent inhibitors of prolyl oligopeptidase (POP)" @default.
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• W2100091027 doi "https://doi.org/10.1016/j.bmcl.2008.06.067" @default.
• W2100091027 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18606544" @default.
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