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- W2100092067 abstract "<b><i>Background:</i></b> The relationship between serum hormone levels and adolescent acne is not fully clarified. <b><i>Objective:</i></b> To determine the relationship between levels of androstenedione, dehydroepiandrosterone sulfate (DHEA-S), testosterone, estradiol and 17α-hydroxyprogesterone (17-OHP) with adolescent acne in Northeast China. <b><i>Methods:</i></b> A transversal study included 242 acne cases and 188 controls. All data were analyzed using SPSS version 17.0. <b><i>Results:</i></b> Androstenedione and testosterone levels were significantly higher (p < 0.0001) in the cases than in the control group. In males, the difference in 17-OHP levels was statistically significant (p < 0.0001), as well as between mild and severe acne cases (p = 0.002). The estradiol level was significantly different (p < 0.0001) between cases and controls in females. <b><i>Conclusion:</i></b> Higher androstenedione and testosterone levels are significant risk factors in the occurrence of adolescent acne. A higher 17-OHP level aggravates the severity of male adolescent acne, while a higher estradiol level protects females against the onset of adolescent acne." @default.
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- W2100092067 date "2014-01-01" @default.
- W2100092067 modified "2023-09-27" @default.
- W2100092067 title "Higher 17a-Hydroxyprogesterone Levels Aggravated the Severity of Male Adolescent Acne in Northeast China" @default.
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- W2100092067 doi "https://doi.org/10.1159/000365656" @default.
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