FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2100092655> ?p ?o ?g. }

• W2100092655 endingPage "483" @default.
• W2100092655 startingPage "479" @default.
• W2100092655 abstract "Background Ischemic stroke and other vascular outcomes occur in 10–20% of patients in the three-months following a transient ischemic attack or minor ischemic stroke, and many are disabling. The highest risk period for these outcomes is the early hours and days immediately following the ischemic event. Aspirin is the most common antithrombotic treatment used for these patients. Aim The aim of POINT is to determine whether clopidogrel plus aspirin taken <12 h after transient ischemic attack or minor ischemic stroke symptom onset is more effective in preventing major ischemic vascular events at 90 days in the high-risk, and acceptably safe, compared with aspirin alone. Design POINT is a prospective, randomized, double-blind, multicenter trial in patients with transient ischemic attack or minor ischemic stroke. Subjects are randomized to clopidogrel (600 mg loading dose followed by 75 mg/day) or matching placebo, and all will receive open-label aspirin 50–325 mg/day, with a dose of 162 mg daily for five-days followed by 81 mg daily strongly recommended. Study Outcomes The primary efficacy outcome is the composite of new ischemic vascular events — ischemic stroke, myocardial infarction, or ischemic vascular death — by 90 days. The primary safety outcome is major hemorrhage, which includes symptomatic intracranial hemorrhage. Discussion Aspirin is the most common antithrombotic given to patients with a stroke or transient ischemic attack, as it reduces the risk of subsequent stroke. This trial expects to determine whether more aggressive antithrombotic therapy with clopidogrel plus aspirin, initiated acutely, is more effective than aspirin alone." @default.
• W2100092655 created "2016-06-24" @default.
• W2100092655 creator A5001594817 @default.
• W2100092655 creator A5003562662 @default.
• W2100092655 creator A5028929566 @default.
• W2100092655 creator A5031383231 @default.
• W2100092655 creator A5040093844 @default.
• W2100092655 creator A5044011993 @default.
• W2100092655 creator A5051630792 @default.
• W2100092655 creator A5059445912 @default.
• W2100092655 creator A5072880755 @default.
• W2100092655 creator A5079153413 @default.
• W2100092655 creator A5083340584 @default.
• W2100092655 creator A5087667863 @default.
• W2100092655 date "2013-07-23" @default.
• W2100092655 modified "2023-10-01" @default.
• W2100092655 title "Platelet-Oriented Inhibition in New TIA and Minor Ischemic Stroke (POINT) Trial: Rationale and design" @default.
• W2100092655 cites W1963598365 @default.
• W2100092655 cites W1963748801 @default.
• W2100092655 cites W1979730105 @default.
• W2100092655 cites W1988809488 @default.
• W2100092655 cites W2006054403 @default.
• W2100092655 cites W2027123157 @default.
• W2100092655 cites W2045003342 @default.
• W2100092655 cites W2058495023 @default.
• W2100092655 cites W2068419057 @default.
• W2100092655 cites W2076482318 @default.
• W2100092655 cites W2080670989 @default.
• W2100092655 cites W2108825346 @default.
• W2100092655 cites W2111089169 @default.
• W2100092655 cites W2113089341 @default.
• W2100092655 cites W2118088092 @default.
• W2100092655 cites W2126985226 @default.
• W2100092655 cites W2132247347 @default.
• W2100092655 cites W2137539662 @default.
• W2100092655 cites W2142021807 @default.
• W2100092655 cites W2148919757 @default.
• W2100092655 cites W2165920141 @default.
• W2100092655 cites W2170765765 @default.
• W2100092655 cites W2397867274 @default.
• W2100092655 cites W2989714602 @default.
• W2100092655 cites W4240294852 @default.
• W2100092655 cites W906589 @default.
• W2100092655 doi "https://doi.org/10.1111/ijs.12129" @default.
• W2100092655 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4412261" @default.
• W2100092655 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23879752" @default.
• W2100092655 hasPublicationYear "2013" @default.
• W2100092655 type Work @default.
• W2100092655 sameAs 2100092655 @default.
• W2100092655 citedByCount "123" @default.
• W2100092655 countsByYear W21000926552014 @default.
• W2100092655 countsByYear W21000926552015 @default.
• W2100092655 countsByYear W21000926552016 @default.
• W2100092655 countsByYear W21000926552017 @default.
• W2100092655 countsByYear W21000926552018 @default.
• W2100092655 countsByYear W21000926552019 @default.
• W2100092655 countsByYear W21000926552020 @default.
• W2100092655 countsByYear W21000926552021 @default.
• W2100092655 countsByYear W21000926552022 @default.
• W2100092655 countsByYear W21000926552023 @default.
• W2100092655 crossrefType "journal-article" @default.
• W2100092655 hasAuthorship W2100092655A5001594817 @default.
• W2100092655 hasAuthorship W2100092655A5003562662 @default.
• W2100092655 hasAuthorship W2100092655A5028929566 @default.
• W2100092655 hasAuthorship W2100092655A5031383231 @default.
• W2100092655 hasAuthorship W2100092655A5040093844 @default.
• W2100092655 hasAuthorship W2100092655A5044011993 @default.
• W2100092655 hasAuthorship W2100092655A5051630792 @default.
• W2100092655 hasAuthorship W2100092655A5059445912 @default.
• W2100092655 hasAuthorship W2100092655A5072880755 @default.
• W2100092655 hasAuthorship W2100092655A5079153413 @default.
• W2100092655 hasAuthorship W2100092655A5083340584 @default.
• W2100092655 hasAuthorship W2100092655A5087667863 @default.
• W2100092655 hasBestOaLocation W21000926552 @default.
• W2100092655 hasConcept C126322002 @default.
• W2100092655 hasConcept C127413603 @default.
• W2100092655 hasConcept C164705383 @default.
• W2100092655 hasConcept C168563851 @default.
• W2100092655 hasConcept C203092338 @default.
• W2100092655 hasConcept C2777015399 @default.
• W2100092655 hasConcept C2777466421 @default.
• W2100092655 hasConcept C2777628954 @default.
• W2100092655 hasConcept C2777849778 @default.
• W2100092655 hasConcept C2780645631 @default.
• W2100092655 hasConcept C2909112448 @default.
• W2100092655 hasConcept C42219234 @default.
• W2100092655 hasConcept C71924100 @default.
• W2100092655 hasConcept C78519656 @default.
• W2100092655 hasConceptScore W2100092655C126322002 @default.
• W2100092655 hasConceptScore W2100092655C127413603 @default.
• W2100092655 hasConceptScore W2100092655C164705383 @default.
• W2100092655 hasConceptScore W2100092655C168563851 @default.
• W2100092655 hasConceptScore W2100092655C203092338 @default.
• W2100092655 hasConceptScore W2100092655C2777015399 @default.
• W2100092655 hasConceptScore W2100092655C2777466421 @default.
• W2100092655 hasConceptScore W2100092655C2777628954 @default.
• W2100092655 hasConceptScore W2100092655C2777849778 @default.
• W2100092655 hasConceptScore W2100092655C2780645631 @default.

• next