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- W2100096634 abstract "Rab guanosine triphosphatases regulate vesicular transport and membrane traffic within eukaryotic cells. Here, a kinesin-like protein that interacts with guanosine triphosphate (GTP)-bound forms of Rab6 was identified. This protein, termed Rabkinesin-6, was localized to the Golgi apparatus and shown to play a role in the dynamics of this organelle. The carboxyl-terminal domain of Rabkinesin-6, which contains the Rab6-interacting domain, inhibited the effects of Rab6-GTP on intracellular transport. Thus, a molecular motor is a potential effector of a Rab protein, and coordinated action between members of these two families of proteins could control membrane dynamics and directional vesicular traffic." @default.
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- W2100096634 date "1998-01-23" @default.
- W2100096634 modified "2023-09-30" @default.
- W2100096634 title "Interaction of a Golgi-Associated Kinesin-Like Protein with Rab6" @default.
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- W2100096634 doi "https://doi.org/10.1126/science.279.5350.580" @default.
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