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- W2100120771 abstract "Innate-like lymphocytes (ILLs) and innate lymphoid cells (ILCs) are two newly characterized families of lymphocytes with limited and no rearranged antigen receptors, respectively. These soldiers provide a first line of defense against foreign insults by triggering a prompt innate immune response and bridging the gap of innate and adaptive immunity. Type 2 innate lymphoid cells (ILCs2) are newly identified members of the ILC family that play a key role in type 2 immune responses by prompt production of type 2 cytokines (especially IL-5 and IL-13) in response to antigen-induced IL-25/33 and by recruiting type 2 “immune franchise.” Regarding the two different roles of type 2 cytokines, helminth expulsion and type 2-related diseases, here we review the latest advances in ILC2 biology and examine the pivotal role of resident ILCs2 in allergen-specific airway inflammation and asthma." @default.
- W2100120771 created "2016-06-24" @default.
- W2100120771 creator A5000694982 @default.
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- W2100120771 date "2012-11-11" @default.
- W2100120771 modified "2023-10-11" @default.
- W2100120771 title "Type 2 Innate Lymphoid Cells: Friends or Foes—Role in Airway Allergic Inflammation and Asthma" @default.
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- W2100120771 doi "https://doi.org/10.1155/2012/130937" @default.
- W2100120771 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3503334" @default.
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