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• W2100144505 abstract "Diphenylhydantoin (phenytoin) is a widely used drug with multiple adverse effects, several of them cutaneous. Prenatal exposure to hydantoins may result in a spectrum of structural, developmental, and behavioral changes known as the fetal hydantoin syndrome (FHS). A patient with the dysmorphic characteristics of FHS had unusual hyperpigmentation of several fingernails, a finding which has not been described in other patients with FHS. We propose a mechanism for the dysmorphic action of phenytoin on the developing fetus, consonant with the known effects of hydantoins on collagen metabolism." @default.
• W2100144505 created "2016-06-24" @default.
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• W2100144505 date "1981-08-01" @default.
• W2100144505 modified "2023-10-13" @default.
• W2100144505 title "Dilantin digital defects" @default.
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• W2100144505 doi "https://doi.org/10.1016/s0190-9622(81)70087-2" @default.
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