FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2100290573> ?p ?o ?g. }

• W2100290573 endingPage "634" @default.
• W2100290573 startingPage "611" @default.
• W2100290573 abstract "▪ Abstract Heterochrony describes the phylogenetic variation in the relative timing of major developmental events. Such heterochronic variation has been noted across phylogeny, including closely related species, suggesting that particular genetic loci control global aspects of developmental timing, and that variation at those loci may play important roles in evolutionary change. Genetic analyses of heterochronic mutations in the nematode Caenorhabditis elegans reveal that control of temporal patterning is analogous to the dedicated genetic pathways that control the patterning of the spatial axes in Drosophila and other metazoans. These pathways generate graded or binary levels of regulatory factors that pattern particular axes of the developing animal. C. elegans heterochronic genes constitute a regulatory cascade that both generates a temporal decrease in the level of the LIN-14 and LIN-28 proteins and responds to the changes in these gene activities to coordinate the temporal sequence of many cell fates as the animal develops. The temporal regulation of lin-14 and lin-28 gene activities is posttranscriptional and mediated by the antisense RNA product of the lin-4 gene. Hormonal control of developmental timing is a common theme throughout phylogeny. Heterochronic genes that involve hormonal signaling have been identified in vertebrates as well as C. elegans." @default.
• W2100290573 created "2016-06-24" @default.
• W2100290573 creator A5013989133 @default.
• W2100290573 creator A5066998461 @default.
• W2100290573 date "1997-12-01" @default.
• W2100290573 modified "2023-09-27" @default.
• W2100290573 title "TEMPORAL PATTERN FORMATION BY HETEROCHRONIC GENES" @default.
• W2100290573 cites W150253041 @default.
• W2100290573 cites W1521553309 @default.
• W2100290573 cites W1855865876 @default.
• W2100290573 cites W1967022871 @default.
• W2100290573 cites W1976851982 @default.
• W2100290573 cites W1977589334 @default.
• W2100290573 cites W1986006829 @default.
• W2100290573 cites W1988006678 @default.
• W2100290573 cites W1989952069 @default.
• W2100290573 cites W1991285508 @default.
• W2100290573 cites W1991437365 @default.
• W2100290573 cites W1991484745 @default.
• W2100290573 cites W2006577331 @default.
• W2100290573 cites W2011389479 @default.
• W2100290573 cites W2011768171 @default.
• W2100290573 cites W2019259664 @default.
• W2100290573 cites W2020100801 @default.
• W2100290573 cites W2025317003 @default.
• W2100290573 cites W2030869191 @default.
• W2100290573 cites W2032264626 @default.
• W2100290573 cites W2046448941 @default.
• W2100290573 cites W2049251530 @default.
• W2100290573 cites W2050054880 @default.
• W2100290573 cites W2056378879 @default.
• W2100290573 cites W2062376760 @default.
• W2100290573 cites W2063799895 @default.
• W2100290573 cites W2066204446 @default.
• W2100290573 cites W2067008621 @default.
• W2100290573 cites W2071587854 @default.
• W2100290573 cites W2073365784 @default.
• W2100290573 cites W2073828263 @default.
• W2100290573 cites W2085702305 @default.
• W2100290573 cites W2104240619 @default.
• W2100290573 cites W2116362436 @default.
• W2100290573 cites W2119031123 @default.
• W2100290573 cites W2120809584 @default.
• W2100290573 cites W2121701144 @default.
• W2100290573 cites W2122336578 @default.
• W2100290573 cites W2138664009 @default.
• W2100290573 cites W2143818366 @default.
• W2100290573 cites W2156491803 @default.
• W2100290573 cites W2160467221 @default.
• W2100290573 cites W2164246885 @default.
• W2100290573 cites W2167884543 @default.
• W2100290573 cites W2182320830 @default.
• W2100290573 cites W2283764724 @default.
• W2100290573 cites W2323243413 @default.
• W2100290573 cites W2337777109 @default.
• W2100290573 doi "https://doi.org/10.1146/annurev.genet.31.1.611" @default.
• W2100290573 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9442909" @default.
• W2100290573 hasPublicationYear "1997" @default.
• W2100290573 type Work @default.
• W2100290573 sameAs 2100290573 @default.
• W2100290573 citedByCount "103" @default.
• W2100290573 countsByYear W21002905732012 @default.
• W2100290573 countsByYear W21002905732013 @default.
• W2100290573 countsByYear W21002905732014 @default.
• W2100290573 countsByYear W21002905732015 @default.
• W2100290573 countsByYear W21002905732016 @default.
• W2100290573 countsByYear W21002905732017 @default.
• W2100290573 countsByYear W21002905732018 @default.
• W2100290573 countsByYear W21002905732019 @default.
• W2100290573 countsByYear W21002905732020 @default.
• W2100290573 countsByYear W21002905732021 @default.
• W2100290573 countsByYear W21002905732022 @default.
• W2100290573 countsByYear W21002905732023 @default.
• W2100290573 crossrefType "journal-article" @default.
• W2100290573 hasAuthorship W2100290573A5013989133 @default.
• W2100290573 hasAuthorship W2100290573A5066998461 @default.
• W2100290573 hasConcept C104317684 @default.
• W2100290573 hasConcept C168601633 @default.
• W2100290573 hasConcept C169503297 @default.
• W2100290573 hasConcept C2776496032 @default.
• W2100290573 hasConcept C2778944004 @default.
• W2100290573 hasConcept C37291498 @default.
• W2100290573 hasConcept C54355233 @default.
• W2100290573 hasConcept C78458016 @default.
• W2100290573 hasConcept C86803240 @default.
• W2100290573 hasConcept C90132467 @default.
• W2100290573 hasConceptScore W2100290573C104317684 @default.
• W2100290573 hasConceptScore W2100290573C168601633 @default.
• W2100290573 hasConceptScore W2100290573C169503297 @default.
• W2100290573 hasConceptScore W2100290573C2776496032 @default.
• W2100290573 hasConceptScore W2100290573C2778944004 @default.
• W2100290573 hasConceptScore W2100290573C37291498 @default.
• W2100290573 hasConceptScore W2100290573C54355233 @default.
• W2100290573 hasConceptScore W2100290573C78458016 @default.
• W2100290573 hasConceptScore W2100290573C86803240 @default.
• W2100290573 hasConceptScore W2100290573C90132467 @default.
• W2100290573 hasIssue "1" @default.
• W2100290573 hasLocation W21002905731 @default.

• next