FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2100381566> ?p ?o ?g. }

• W2100381566 endingPage "8050" @default.
• W2100381566 startingPage "8038" @default.
• W2100381566 abstract "Splicing of human immunodeficiency virus type 1 (HIV-1) exon 6D is regulated by the presence of a complex splicing regulatory element (SRE) sequence that interacts with the splicing factors hnRNP H and SC35. In this work, we show that, in the context of the wild-type viral sequence, hnRNP H acts as a repressor of exon 6D inclusion independent of its binding to the SRE. However, hnRNP H binding to the SRE acts as an enhancer of exon 6D inclusion in the presence of a critical T-to-C mutation. These seemingly contrasting functional properties of hnRNP H appear to be caused by a change in the RNA secondary structure induced by the T-to-C mutation that affects the spatial location of bound hnRNP H with respect to the exon 6D splicing determinants. We propose a new regulatory mechanism mediated by RNA folding that may also explain the dual properties of hnRNP H in splicing regulation." @default.
• W2100381566 created "2016-06-24" @default.
• W2100381566 creator A5032436476 @default.
• W2100381566 creator A5049573123 @default.
• W2100381566 creator A5077686306 @default.
• W2100381566 creator A5083854775 @default.
• W2100381566 date "2008-08-15" @default.
• W2100381566 modified "2023-10-14" @default.
• W2100381566 title "The Secondary Structure of the Human Immunodeficiency Virus Type 1 Transcript Modulates Viral Splicing and Infectivity" @default.
• W2100381566 cites W1594935738 @default.
• W2100381566 cites W1660920549 @default.
• W2100381566 cites W1880169023 @default.
• W2100381566 cites W1948969711 @default.
• W2100381566 cites W1976249889 @default.
• W2100381566 cites W1984706997 @default.
• W2100381566 cites W1988303029 @default.
• W2100381566 cites W2016348135 @default.
• W2100381566 cites W2028529478 @default.
• W2100381566 cites W2036399606 @default.
• W2100381566 cites W2055583355 @default.
• W2100381566 cites W2057544210 @default.
• W2100381566 cites W2058737848 @default.
• W2100381566 cites W2061930808 @default.
• W2100381566 cites W2064664075 @default.
• W2100381566 cites W2080489609 @default.
• W2100381566 cites W2091907886 @default.
• W2100381566 cites W2100998712 @default.
• W2100381566 cites W2101131361 @default.
• W2100381566 cites W2103018204 @default.
• W2100381566 cites W2103065204 @default.
• W2100381566 cites W2108007340 @default.
• W2100381566 cites W2111032921 @default.
• W2100381566 cites W2113038023 @default.
• W2100381566 cites W2119815283 @default.
• W2100381566 cites W2120049843 @default.
• W2100381566 cites W2123301059 @default.
• W2100381566 cites W2124050134 @default.
• W2100381566 cites W2128893980 @default.
• W2100381566 cites W2130922965 @default.
• W2100381566 cites W2136898333 @default.
• W2100381566 cites W2141157874 @default.
• W2100381566 cites W2142224176 @default.
• W2100381566 cites W2146478787 @default.
• W2100381566 cites W2146723875 @default.
• W2100381566 cites W2159864549 @default.
• W2100381566 cites W2164874571 @default.
• W2100381566 cites W2167968442 @default.
• W2100381566 cites W2352074560 @default.
• W2100381566 doi "https://doi.org/10.1128/jvi.00721-08" @default.
• W2100381566 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2519558" @default.
• W2100381566 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18550660" @default.
• W2100381566 hasPublicationYear "2008" @default.
• W2100381566 type Work @default.
• W2100381566 sameAs 2100381566 @default.
• W2100381566 citedByCount "30" @default.
• W2100381566 countsByYear W21003815662012 @default.
• W2100381566 countsByYear W21003815662013 @default.
• W2100381566 countsByYear W21003815662014 @default.
• W2100381566 countsByYear W21003815662015 @default.
• W2100381566 countsByYear W21003815662016 @default.
• W2100381566 countsByYear W21003815662017 @default.
• W2100381566 countsByYear W21003815662018 @default.
• W2100381566 countsByYear W21003815662019 @default.
• W2100381566 countsByYear W21003815662020 @default.
• W2100381566 countsByYear W21003815662022 @default.
• W2100381566 countsByYear W21003815662023 @default.
• W2100381566 crossrefType "journal-article" @default.
• W2100381566 hasAuthorship W2100381566A5032436476 @default.
• W2100381566 hasAuthorship W2100381566A5049573123 @default.
• W2100381566 hasAuthorship W2100381566A5077686306 @default.
• W2100381566 hasAuthorship W2100381566A5083854775 @default.
• W2100381566 hasBestOaLocation W21003815661 @default.
• W2100381566 hasConcept C104317684 @default.
• W2100381566 hasConcept C111936080 @default.
• W2100381566 hasConcept C150194340 @default.
• W2100381566 hasConcept C153911025 @default.
• W2100381566 hasConcept C159047783 @default.
• W2100381566 hasConcept C166342232 @default.
• W2100381566 hasConcept C194583182 @default.
• W2100381566 hasConcept C36823959 @default.
• W2100381566 hasConcept C42576000 @default.
• W2100381566 hasConcept C54355233 @default.
• W2100381566 hasConcept C54458228 @default.
• W2100381566 hasConcept C67705224 @default.
• W2100381566 hasConcept C85468374 @default.
• W2100381566 hasConcept C86803240 @default.
• W2100381566 hasConcept C94671646 @default.
• W2100381566 hasConceptScore W2100381566C104317684 @default.
• W2100381566 hasConceptScore W2100381566C111936080 @default.
• W2100381566 hasConceptScore W2100381566C150194340 @default.
• W2100381566 hasConceptScore W2100381566C153911025 @default.
• W2100381566 hasConceptScore W2100381566C159047783 @default.
• W2100381566 hasConceptScore W2100381566C166342232 @default.
• W2100381566 hasConceptScore W2100381566C194583182 @default.
• W2100381566 hasConceptScore W2100381566C36823959 @default.
• W2100381566 hasConceptScore W2100381566C42576000 @default.
• W2100381566 hasConceptScore W2100381566C54355233 @default.
• W2100381566 hasConceptScore W2100381566C54458228 @default.

• next