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- W2100387617 endingPage "L12" @default.
- W2100387617 startingPage "L3" @default.
- W2100387617 abstract "A vast number of studies on the unfavorable effects of secondhand smoke (SHS) exist within the international literature, the majority of which evaluate longitudinal epidemiological data. Although limited, the experimental studies that assess the acute and short-term effects of exposure to SHS are also increasing in number. They include cellular, animal, and human studies that indicate a number of pathophysiological mechanisms through which the deleterious effects of SHS may arise. This current review evaluates the existing biological evidence regarding the acute health effects of SHS exposure. Analyses on the inhaled toxicants and the carcinogenicity of SHS are included as well as in-depth discussions on the evidence for acute SHS-induced respiratory, cardiovascular, metabolic, endocrine and immune effects, and SHS-induced influences on oxygen delivery and exercise. The influence of the length of exposure and the duration of the observed effects is also described. Moreover, recent findings regarding the underlying pathophysiological mechanisms related to SHS are depicted so as to generate models that describe the SHS-induced effects on different systems within the human body. Based on the presented biological evidence, it is concluded that brief, acute, transient exposures to SHS may cause significant adverse effects on several systems of the human body and represent a significant and acute health hazard. Future research directions in this area include research on the concentrations of tobacco smoke constituents in the alveolar milieu following SHS exposure, individual susceptibility to SHS, as well as the effects of SHS on neurobehavioral activity, brain cell development, synaptic development, and function." @default.
- W2100387617 created "2016-06-24" @default.
- W2100387617 creator A5002388268 @default.
- W2100387617 creator A5035866222 @default.
- W2100387617 creator A5045905012 @default.
- W2100387617 creator A5073434880 @default.
- W2100387617 creator A5081619309 @default.
- W2100387617 date "2010-01-01" @default.
- W2100387617 modified "2023-10-15" @default.
- W2100387617 title "Biological evidence for the acute health effects of secondhand smoke exposure" @default.
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