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• W2100400650 endingPage "290" @default.
• W2100400650 startingPage "273" @default.
• W2100400650 abstract "Abstract Neuropathy is a common complication of end‐stage kidney disease (ESKD), typically presenting as a distal symmetrical process with greater lower‐limb than upper‐limb involvement. The condition is of insidious onset, progressing over months. and has been estimated to be present in 60%–100% of patients on dialysis. Neuropathy generally only develops at glomerular filtration rates of less than 12 ml/min. The most frequent clinical features reflect large‐fiber involvement, with paresthesias, reduction in deep tendon reflexes, impaired vibration sense, muscle wasting, and weakness. Nerve conduction studies demonstrate findings consistent with a generalized neuropathy of the axonal type. Patients may also develop autonomic features, with postural hypotension, impaired sweating, diarrhea, constipation, or impotence. The development of uremic neuropathy has been related previously to the retention of neurotoxic molecules in the middle molecular range, although this hypothesis lacked formal proof. Studies utilizing novel axonal excitability techniques have recently shed further light on the pathophysiology of this condition. Nerves of uremic patients have been shown to exist in a chronically depolarized state prior to dialysis, with subsequent improvement and normalization of resting membrane potential after dialysis. The degree of depolarization correlates with serum K + , suggesting that chronic hyperkalemic depolarization plays an important role in the development of nerve dysfunction in ESKD. These recent findings suggest that maintenance of serum K + within normal limits between periods of dialysis, rather than simple avoidance of hyperkalemia, is likely to reduce the incidence and severity of uremic neuropathy. Muscle Nerve, 2006" @default.
• W2100400650 created "2016-06-24" @default.
• W2100400650 creator A5005224523 @default.
• W2100400650 creator A5060424866 @default.
• W2100400650 date "2006-12-28" @default.
• W2100400650 modified "2023-10-15" @default.
• W2100400650 title "Uremic neuropathy: Clinical features and new pathophysiological insights" @default.
• W2100400650 cites W1485374795 @default.
• W2100400650 cites W1559519019 @default.
• W2100400650 cites W1761785605 @default.
• W2100400650 cites W1964112923 @default.
• W2100400650 cites W1964177344 @default.
• W2100400650 cites W1965061041 @default.
• W2100400650 cites W1967888111 @default.
• W2100400650 cites W1974344237 @default.
• W2100400650 cites W1975696802 @default.
• W2100400650 cites W1975918033 @default.
• W2100400650 cites W1976595456 @default.
• W2100400650 cites W1976899302 @default.
• W2100400650 cites W1978662622 @default.
• W2100400650 cites W1981465968 @default.
• W2100400650 cites W1981650185 @default.
• W2100400650 cites W1984200669 @default.
• W2100400650 cites W1986073253 @default.
• W2100400650 cites W1986744802 @default.
• W2100400650 cites W1990122916 @default.
• W2100400650 cites W1992133502 @default.
• W2100400650 cites W1992868186 @default.
• W2100400650 cites W1994450293 @default.
• W2100400650 cites W1994494476 @default.
• W2100400650 cites W1996412409 @default.
• W2100400650 cites W1998008037 @default.
• W2100400650 cites W2000459171 @default.
• W2100400650 cites W2004113422 @default.
• W2100400650 cites W2005941970 @default.
• W2100400650 cites W2006381155 @default.
• W2100400650 cites W2006618634 @default.
• W2100400650 cites W2008579620 @default.
• W2100400650 cites W2009644643 @default.
• W2100400650 cites W2010668206 @default.
• W2100400650 cites W2010891625 @default.
• W2100400650 cites W2011512369 @default.
• W2100400650 cites W2014081332 @default.
• W2100400650 cites W2014676629 @default.
• W2100400650 cites W2015646028 @default.
• W2100400650 cites W2017031047 @default.
• W2100400650 cites W2018403527 @default.
• W2100400650 cites W2019384650 @default.
• W2100400650 cites W2019768860 @default.
• W2100400650 cites W2021673459 @default.
• W2100400650 cites W2022055420 @default.
• W2100400650 cites W2022189256 @default.
• W2100400650 cites W2022765359 @default.
• W2100400650 cites W2022874561 @default.
• W2100400650 cites W2023567372 @default.
• W2100400650 cites W2024565707 @default.
• W2100400650 cites W2026499401 @default.
• W2100400650 cites W2028531738 @default.
• W2100400650 cites W2029454513 @default.
• W2100400650 cites W2030545868 @default.
• W2100400650 cites W2031422758 @default.
• W2100400650 cites W2032212682 @default.
• W2100400650 cites W2033110613 @default.
• W2100400650 cites W2036701724 @default.
• W2100400650 cites W2037867442 @default.
• W2100400650 cites W2044943747 @default.
• W2100400650 cites W2045873456 @default.
• W2100400650 cites W2047940580 @default.
• W2100400650 cites W2048734122 @default.
• W2100400650 cites W2049601742 @default.
• W2100400650 cites W2050598006 @default.
• W2100400650 cites W2053702262 @default.
• W2100400650 cites W2057913235 @default.
• W2100400650 cites W2060195117 @default.
• W2100400650 cites W2060628866 @default.
• W2100400650 cites W2061269295 @default.
• W2100400650 cites W2062897932 @default.
• W2100400650 cites W2063476798 @default.
• W2100400650 cites W2064404169 @default.
• W2100400650 cites W2064848556 @default.
• W2100400650 cites W2064849323 @default.
• W2100400650 cites W2066188245 @default.
• W2100400650 cites W2066225734 @default.
• W2100400650 cites W2067372243 @default.
• W2100400650 cites W2068250294 @default.
• W2100400650 cites W2069050515 @default.
• W2100400650 cites W2070537212 @default.
• W2100400650 cites W2072033828 @default.
• W2100400650 cites W2072368191 @default.
• W2100400650 cites W2072673945 @default.
• W2100400650 cites W2074221454 @default.
• W2100400650 cites W2075651763 @default.
• W2100400650 cites W2077710610 @default.
• W2100400650 cites W2079268018 @default.
• W2100400650 cites W2079863333 @default.
• W2100400650 cites W2080102553 @default.
• W2100400650 cites W2083189240 @default.
• W2100400650 cites W2084467852 @default.

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