Matches in SemOpenAlex for { <https://semopenalex.org/work/W2100404198> ?p ?o ?g. }
- W2100404198 endingPage "1340" @default.
- W2100404198 startingPage "1331" @default.
- W2100404198 abstract "The activity of cytochrome oxidase (CO), a mitochondrial enzyme of oxidative energy metabolism, is regulated by nerve cell functional activity. The mechanism of CO activity regulation was studied using histochemical and immunohistochemical methods to show the distributions of CO activity and protein, respectively, in the macaque monkey visual system under normal and experimental conditions. In normal animals, patterns of CO activity were found to reflect underlying patterns of CO protein distribution; for example, puffs of high CO activity in cortical area 17 contained high levels of CO protein. Experimental animals were injected monocularly with TTX for 3–4 weeks; this treatment blocks retinal impulses in the injected eye and results in decreased CO activity in lateral geniculate laminae and striate cortical columns normally driven by the treated eye. The experimentally induced decreases in CO activity were also found to reflect underlying parallel decreases in CO protein levels. These results suggest that CO activity is regulated mainly at the level of the local amount rather than the turnover number of the enzyme and imply that the rates of CO synthesis and/or degradation are regulated by neural functional activity." @default.
- W2100404198 created "2016-06-24" @default.
- W2100404198 creator A5041026882 @default.
- W2100404198 creator A5053646636 @default.
- W2100404198 date "1990-04-01" @default.
- W2100404198 modified "2023-09-24" @default.
- W2100404198 title "Regulation of cytochrome oxidase protein levels by functional activity in the macaque monkey visual system" @default.
- W2100404198 cites W126252753 @default.
- W2100404198 cites W1527237994 @default.
- W2100404198 cites W1543342841 @default.
- W2100404198 cites W1550383108 @default.
- W2100404198 cites W1557948809 @default.
- W2100404198 cites W1570587801 @default.
- W2100404198 cites W1614200591 @default.
- W2100404198 cites W1843383581 @default.
- W2100404198 cites W1979741733 @default.
- W2100404198 cites W1979749697 @default.
- W2100404198 cites W1986408039 @default.
- W2100404198 cites W1986517387 @default.
- W2100404198 cites W1987906661 @default.
- W2100404198 cites W1994878858 @default.
- W2100404198 cites W1998295152 @default.
- W2100404198 cites W2004976934 @default.
- W2100404198 cites W2009037137 @default.
- W2100404198 cites W2015282923 @default.
- W2100404198 cites W2015351171 @default.
- W2100404198 cites W2022236306 @default.
- W2100404198 cites W2033665082 @default.
- W2100404198 cites W2041894106 @default.
- W2100404198 cites W2051240076 @default.
- W2100404198 cites W2056810710 @default.
- W2100404198 cites W2067210431 @default.
- W2100404198 cites W2071417227 @default.
- W2100404198 cites W2072154749 @default.
- W2100404198 cites W2072569787 @default.
- W2100404198 cites W2075822968 @default.
- W2100404198 cites W2081874619 @default.
- W2100404198 cites W2090535332 @default.
- W2100404198 cites W2095052471 @default.
- W2100404198 cites W2104228780 @default.
- W2100404198 cites W2118419827 @default.
- W2100404198 cites W2122625397 @default.
- W2100404198 cites W2162079383 @default.
- W2100404198 cites W44824404 @default.
- W2100404198 doi "https://doi.org/10.1523/jneurosci.10-04-01331.1990" @default.
- W2100404198 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6570214" @default.
- W2100404198 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2158531" @default.
- W2100404198 hasPublicationYear "1990" @default.
- W2100404198 type Work @default.
- W2100404198 sameAs 2100404198 @default.
- W2100404198 citedByCount "106" @default.
- W2100404198 countsByYear W21004041982012 @default.
- W2100404198 countsByYear W21004041982013 @default.
- W2100404198 countsByYear W21004041982016 @default.
- W2100404198 countsByYear W21004041982017 @default.
- W2100404198 countsByYear W21004041982021 @default.
- W2100404198 crossrefType "journal-article" @default.
- W2100404198 hasAuthorship W2100404198A5041026882 @default.
- W2100404198 hasAuthorship W2100404198A5053646636 @default.
- W2100404198 hasBestOaLocation W21004041981 @default.
- W2100404198 hasConcept C123249941 @default.
- W2100404198 hasConcept C126322002 @default.
- W2100404198 hasConcept C169760540 @default.
- W2100404198 hasConcept C181199279 @default.
- W2100404198 hasConcept C185592680 @default.
- W2100404198 hasConcept C186060115 @default.
- W2100404198 hasConcept C198684833 @default.
- W2100404198 hasConcept C2778950215 @default.
- W2100404198 hasConcept C2780827179 @default.
- W2100404198 hasConcept C28212737 @default.
- W2100404198 hasConcept C2984127161 @default.
- W2100404198 hasConcept C2993927895 @default.
- W2100404198 hasConcept C55493867 @default.
- W2100404198 hasConcept C57600042 @default.
- W2100404198 hasConcept C71924100 @default.
- W2100404198 hasConcept C74254510 @default.
- W2100404198 hasConcept C86803240 @default.
- W2100404198 hasConcept C95444343 @default.
- W2100404198 hasConceptScore W2100404198C123249941 @default.
- W2100404198 hasConceptScore W2100404198C126322002 @default.
- W2100404198 hasConceptScore W2100404198C169760540 @default.
- W2100404198 hasConceptScore W2100404198C181199279 @default.
- W2100404198 hasConceptScore W2100404198C185592680 @default.
- W2100404198 hasConceptScore W2100404198C186060115 @default.
- W2100404198 hasConceptScore W2100404198C198684833 @default.
- W2100404198 hasConceptScore W2100404198C2778950215 @default.
- W2100404198 hasConceptScore W2100404198C2780827179 @default.
- W2100404198 hasConceptScore W2100404198C28212737 @default.
- W2100404198 hasConceptScore W2100404198C2984127161 @default.
- W2100404198 hasConceptScore W2100404198C2993927895 @default.
- W2100404198 hasConceptScore W2100404198C55493867 @default.
- W2100404198 hasConceptScore W2100404198C57600042 @default.
- W2100404198 hasConceptScore W2100404198C71924100 @default.
- W2100404198 hasConceptScore W2100404198C74254510 @default.
- W2100404198 hasConceptScore W2100404198C86803240 @default.
- W2100404198 hasConceptScore W2100404198C95444343 @default.
- W2100404198 hasIssue "4" @default.
- W2100404198 hasLocation W21004041981 @default.