Matches in SemOpenAlex for { <https://semopenalex.org/work/W2100434577> ?p ?o ?g. }
- W2100434577 abstract "Abstract Background Nutritional factors play a major role in cancer initiation and development. Dietary polyunsaturated fatty acids (PUFAs) have the ability to induce modifications in the activity of lipoxygenase (LOX) and cyclooxygenase (COX) enzymes that affect tumour growth. We studied the effect of two diets enriched in 6% Walnut and Peanut oils that are rich in ω-3 and ω9 PUFAs respectively on a murine mammary gland adenocarcinoma as compared with the control (C) that received commercial diet. Results Peanut oil enriched diet induced an increase in membrane arachidonic acid (AA) content and the cyclooxygenase enzyme derived 12-HHT (p < 0.05) and simultaneously showed decrease in 12-LOX, 15-LOX-2, 15-LOX-1 and PGE activities (p < 0.05) that corresponded to higher apoptosis and lower mitosis seen in this group (p < 0.05). Furthermore, Peanut oil group showed lower T-cell infiltration (p < 0.05), number of metastasis (p < 0.05) and tumour volume (p < 0.05) and longer survival rate compared to other groups. Conclusions The results of the present study showed that Peanut oil-enriched diet protects against mammary cancer development by modulating tumour membrane fatty acids composition and LOX and COX enzyme activities." @default.
- W2100434577 created "2016-06-24" @default.
- W2100434577 creator A5003733759 @default.
- W2100434577 creator A5012916366 @default.
- W2100434577 creator A5015190216 @default.
- W2100434577 creator A5041867206 @default.
- W2100434577 creator A5043773386 @default.
- W2100434577 creator A5048786054 @default.
- W2100434577 creator A5077917339 @default.
- W2100434577 date "2010-10-08" @default.
- W2100434577 modified "2023-10-18" @default.
- W2100434577 title "Effect of ω-3 and ω-9 fatty acid rich oils on lipoxygenases and cyclooxygenases enzymes and on the growth of a mammary adenocarcinoma model" @default.
- W2100434577 cites W1596204790 @default.
- W2100434577 cites W1897996585 @default.
- W2100434577 cites W1976664428 @default.
- W2100434577 cites W1986179656 @default.
- W2100434577 cites W1995740586 @default.
- W2100434577 cites W2001982064 @default.
- W2100434577 cites W2005281513 @default.
- W2100434577 cites W2007409181 @default.
- W2100434577 cites W2013171025 @default.
- W2100434577 cites W2013999949 @default.
- W2100434577 cites W2020319741 @default.
- W2100434577 cites W2020430786 @default.
- W2100434577 cites W2023494015 @default.
- W2100434577 cites W2024726092 @default.
- W2100434577 cites W2031882933 @default.
- W2100434577 cites W2035970683 @default.
- W2100434577 cites W2036110632 @default.
- W2100434577 cites W2037850108 @default.
- W2100434577 cites W2043007112 @default.
- W2100434577 cites W2043121463 @default.
- W2100434577 cites W2052438063 @default.
- W2100434577 cites W2061658502 @default.
- W2100434577 cites W2062206476 @default.
- W2100434577 cites W2073738021 @default.
- W2100434577 cites W2076026015 @default.
- W2100434577 cites W2076830125 @default.
- W2100434577 cites W2078317160 @default.
- W2100434577 cites W2078340385 @default.
- W2100434577 cites W2083082142 @default.
- W2100434577 cites W2083497224 @default.
- W2100434577 cites W2088806263 @default.
- W2100434577 cites W2097366516 @default.
- W2100434577 cites W2105821762 @default.
- W2100434577 cites W2106743382 @default.
- W2100434577 cites W2110344360 @default.
- W2100434577 cites W2130183308 @default.
- W2100434577 cites W2131443622 @default.
- W2100434577 cites W2137375900 @default.
- W2100434577 cites W2152340091 @default.
- W2100434577 cites W2156858113 @default.
- W2100434577 cites W2164086031 @default.
- W2100434577 cites W2185162772 @default.
- W2100434577 doi "https://doi.org/10.1186/1476-511x-9-112" @default.
- W2100434577 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2959203" @default.
- W2100434577 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20932327" @default.
- W2100434577 hasPublicationYear "2010" @default.
- W2100434577 type Work @default.
- W2100434577 sameAs 2100434577 @default.
- W2100434577 citedByCount "58" @default.
- W2100434577 countsByYear W21004345772012 @default.
- W2100434577 countsByYear W21004345772013 @default.
- W2100434577 countsByYear W21004345772014 @default.
- W2100434577 countsByYear W21004345772015 @default.
- W2100434577 countsByYear W21004345772016 @default.
- W2100434577 countsByYear W21004345772017 @default.
- W2100434577 countsByYear W21004345772018 @default.
- W2100434577 countsByYear W21004345772019 @default.
- W2100434577 countsByYear W21004345772020 @default.
- W2100434577 countsByYear W21004345772021 @default.
- W2100434577 countsByYear W21004345772022 @default.
- W2100434577 countsByYear W21004345772023 @default.
- W2100434577 crossrefType "journal-article" @default.
- W2100434577 hasAuthorship W2100434577A5003733759 @default.
- W2100434577 hasAuthorship W2100434577A5012916366 @default.
- W2100434577 hasAuthorship W2100434577A5015190216 @default.
- W2100434577 hasAuthorship W2100434577A5041867206 @default.
- W2100434577 hasAuthorship W2100434577A5043773386 @default.
- W2100434577 hasAuthorship W2100434577A5048786054 @default.
- W2100434577 hasAuthorship W2100434577A5077917339 @default.
- W2100434577 hasBestOaLocation W21004345771 @default.
- W2100434577 hasConcept C126322002 @default.
- W2100434577 hasConcept C134018914 @default.
- W2100434577 hasConcept C181199279 @default.
- W2100434577 hasConcept C185592680 @default.
- W2100434577 hasConcept C190283241 @default.
- W2100434577 hasConcept C19038510 @default.
- W2100434577 hasConcept C22894154 @default.
- W2100434577 hasConcept C2778078955 @default.
- W2100434577 hasConcept C2779689624 @default.
- W2100434577 hasConcept C2780857362 @default.
- W2100434577 hasConcept C31903555 @default.
- W2100434577 hasConcept C382228 @default.
- W2100434577 hasConcept C543025807 @default.
- W2100434577 hasConcept C55493867 @default.
- W2100434577 hasConcept C71924100 @default.
- W2100434577 hasConcept C86803240 @default.
- W2100434577 hasConceptScore W2100434577C126322002 @default.
- W2100434577 hasConceptScore W2100434577C134018914 @default.