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• W2100454928 endingPage "152" @default.
• W2100454928 startingPage "141" @default.
• W2100454928 abstract "The Xdh (rosy) gene is one of the best studied in the Drosophila genus from an evolutionary viewpoint. Here we analyze nucleotide variation in a 1875-bp fragment of the second exon of Xdh in Argentinian populations of the cactophilic D. buzzatii and its sibling D. koepferae. The major electrophoretic alleles of D. buzzatii not only lack diagnostic amino acids in the region studied but also differ on average from each other by four to 13 amino acid changes. Our data also suggest that D. buzzatii populations belonging to different phytogeographic regions are not genetically differentiated, whereas D. koepferae exhibits a significant pattern of population structure. The Xdh region studied is twice as polymorphic in D. buzzatii as in D. koepferae. Differences in historical population size or in recombinational environment between species could account for the differences in the level of nucleotide variation. In both species, the Xdh region exhibits a great number of singletons, which significantly departs from the frequency spectrum expected under neutrality for nonsynonymous sites and also for synonymous sites in D. buzzatii. These excesses of singletons could be the signature of a recent population expansion in D. buzzatii, whereas they may be simply explained as the result of negative selection in D. koepferae." @default.
• W2100454928 created "2016-06-24" @default.
• W2100454928 creator A5008576882 @default.
• W2100454928 creator A5035023075 @default.
• W2100454928 creator A5038435737 @default.
• W2100454928 date "2003-10-31" @default.
• W2100454928 modified "2023-09-24" @default.
• W2100454928 title "Comparative Molecular Population Genetics of the Xdh Locus in the Cactophilic Sibling Species Drosophila buzzatii and D. koepferae" @default.
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• W2100454928 doi "https://doi.org/10.1093/molbev/msh006" @default.
• W2100454928 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14595098" @default.
• W2100454928 hasPublicationYear "2003" @default.
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