Matches in SemOpenAlex for { <https://semopenalex.org/work/W2100512944> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2100512944 abstract "The optimal treatment for limited-disease small cell lung cancer (LD-SCLC) in patients aged 75 years or older remains unknown.Elderly patients with LD-SCLC who were treated with chemoradiotherapy were retrospectively reviewed to evaluate their demographic characteristics and the treatment delivery, drug toxicities and antitumor efficacy.Of the 94 LD-SCLC patients treated with chemotherapy and thoracic radiotherapy at the National Cancer Center Hospital between 1998 and 2003, seven (7.4%) were 75 years of age or older. All of the seven patients were in good general condition, with a performance status of 0 or 1. Five and two patients were treated with early and late concurrent chemoradiotherapy, respectively. While the four cycles of chemotherapy could be completed in only four patients, the full dose of radiotherapy was completed in all of the patients. Grade 4 neutropenia and thrombocytopenia were noted in seven and three patients, respectively. Granulocyte-colony stimulating factor support was used in five patients, red blood cell transfusion was administered in two patients and platelet transfusion was administered in one patient. Grade 3 or more severe esophagitis, pneumonitis and neutropenic fever developed in one, two and three patients, respectively, and one patient died of radiation pneumonitis. Complete response was achieved in six patients and partial response in one patient. The median survival time was 24.7 months, with three disease-free survivors for more than 5 years.Concurrent chemoradiotherapy promises to provide long-term benefit with acceptable toxicity for selected patients of LD-SCLC aged 75 years or older." @default.
- W2100512944 created "2016-06-24" @default.
- W2100512944 creator A5020327537 @default.
- W2100512944 creator A5021782707 @default.
- W2100512944 creator A5030587345 @default.
- W2100512944 creator A5035375326 @default.
- W2100512944 creator A5046628885 @default.
- W2100512944 creator A5050855780 @default.
- W2100512944 creator A5053662389 @default.
- W2100512944 creator A5060063956 @default.
- W2100512944 creator A5082354025 @default.
- W2100512944 creator A5090846902 @default.
- W2100512944 date "2012-12-05" @default.
- W2100512944 modified "2023-09-23" @default.
- W2100512944 title "Chemoradiotherapy for Limited-disease Small-cell Lung Cancer in Elderly Patients Aged 75 Years or Older" @default.
- W2100512944 cites W1923792259 @default.
- W2100512944 cites W1991272247 @default.
- W2100512944 cites W1993312546 @default.
- W2100512944 cites W2019041562 @default.
- W2100512944 cites W2039744397 @default.
- W2100512944 cites W2042850412 @default.
- W2100512944 cites W2062668422 @default.
- W2100512944 cites W2076995418 @default.
- W2100512944 cites W2113992452 @default.
- W2100512944 cites W2121717811 @default.
- W2100512944 cites W2139248078 @default.
- W2100512944 cites W2141956703 @default.
- W2100512944 cites W2151595445 @default.
- W2100512944 cites W2160012348 @default.
- W2100512944 cites W2165870910 @default.
- W2100512944 cites W2180933151 @default.
- W2100512944 cites W4241821824 @default.
- W2100512944 doi "https://doi.org/10.1093/jjco/hys197" @default.
- W2100512944 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23225910" @default.
- W2100512944 hasPublicationYear "2012" @default.
- W2100512944 type Work @default.
- W2100512944 sameAs 2100512944 @default.
- W2100512944 citedByCount "5" @default.
- W2100512944 countsByYear W21005129442013 @default.
- W2100512944 countsByYear W21005129442016 @default.
- W2100512944 countsByYear W21005129442017 @default.
- W2100512944 countsByYear W21005129442020 @default.
- W2100512944 crossrefType "journal-article" @default.
- W2100512944 hasAuthorship W2100512944A5020327537 @default.
- W2100512944 hasAuthorship W2100512944A5021782707 @default.
- W2100512944 hasAuthorship W2100512944A5030587345 @default.
- W2100512944 hasAuthorship W2100512944A5035375326 @default.
- W2100512944 hasAuthorship W2100512944A5046628885 @default.
- W2100512944 hasAuthorship W2100512944A5050855780 @default.
- W2100512944 hasAuthorship W2100512944A5053662389 @default.
- W2100512944 hasAuthorship W2100512944A5060063956 @default.
- W2100512944 hasAuthorship W2100512944A5082354025 @default.
- W2100512944 hasAuthorship W2100512944A5090846902 @default.
- W2100512944 hasBestOaLocation W21005129441 @default.
- W2100512944 hasConcept C126322002 @default.
- W2100512944 hasConcept C141071460 @default.
- W2100512944 hasConcept C2776256026 @default.
- W2100512944 hasConcept C2776694085 @default.
- W2100512944 hasConcept C2776907518 @default.
- W2100512944 hasConcept C2777063308 @default.
- W2100512944 hasConcept C2777714996 @default.
- W2100512944 hasConcept C2778424827 @default.
- W2100512944 hasConcept C2779134260 @default.
- W2100512944 hasConcept C2779524853 @default.
- W2100512944 hasConcept C2779920096 @default.
- W2100512944 hasConcept C43270747 @default.
- W2100512944 hasConcept C509974204 @default.
- W2100512944 hasConcept C71924100 @default.
- W2100512944 hasConceptScore W2100512944C126322002 @default.
- W2100512944 hasConceptScore W2100512944C141071460 @default.
- W2100512944 hasConceptScore W2100512944C2776256026 @default.
- W2100512944 hasConceptScore W2100512944C2776694085 @default.
- W2100512944 hasConceptScore W2100512944C2776907518 @default.
- W2100512944 hasConceptScore W2100512944C2777063308 @default.
- W2100512944 hasConceptScore W2100512944C2777714996 @default.
- W2100512944 hasConceptScore W2100512944C2778424827 @default.
- W2100512944 hasConceptScore W2100512944C2779134260 @default.
- W2100512944 hasConceptScore W2100512944C2779524853 @default.
- W2100512944 hasConceptScore W2100512944C2779920096 @default.
- W2100512944 hasConceptScore W2100512944C43270747 @default.
- W2100512944 hasConceptScore W2100512944C509974204 @default.
- W2100512944 hasConceptScore W2100512944C71924100 @default.
- W2100512944 hasLocation W21005129441 @default.
- W2100512944 hasLocation W21005129442 @default.
- W2100512944 hasOpenAccess W2100512944 @default.
- W2100512944 hasPrimaryLocation W21005129441 @default.
- W2100512944 hasRelatedWork W1967576136 @default.
- W2100512944 hasRelatedWork W2009771902 @default.
- W2100512944 hasRelatedWork W2072950001 @default.
- W2100512944 hasRelatedWork W2100512944 @default.
- W2100512944 hasRelatedWork W2146245617 @default.
- W2100512944 hasRelatedWork W2277416945 @default.
- W2100512944 hasRelatedWork W2413700569 @default.
- W2100512944 hasRelatedWork W2414898663 @default.
- W2100512944 hasRelatedWork W2790190982 @default.
- W2100512944 hasRelatedWork W3031482208 @default.
- W2100512944 isParatext "false" @default.
- W2100512944 isRetracted "false" @default.
- W2100512944 magId "2100512944" @default.
- W2100512944 workType "article" @default.