FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2100525080> ?p ?o ?g. }

• W2100525080 endingPage "4201" @default.
• W2100525080 startingPage "4197" @default.
• W2100525080 abstract "Minor trauma to the uterine cervix is supposed to induce local immunity to prevent cervical lesions caused by human papillomavirus (HPV) infection. This study aimed to investigate the local cervical immunity in women with low grade squamous intraepithelial lesion (LSIL) and effects of abrasion after cryosurgery or Pap smear. One hundred women with LSIL and known results of HPV detection were recruited. HPV positive women were randomly divided according to abrasion into cryotherapy and Pap smear observation groups. Cervical tissues and cervico-vaginal lavage (CVL) were collected at 6 and 12 months after allocation. The levels of cytokines at first recruitment were compared with cytokine levels at 6 months after abrasions. The mRNA of IFN-γ , TNF-α and IL-10 in cervical tissues and these cytokines secreted in CVL were determined using real time PCR and ELISA, respectively. Anti-HPV16 IgG and IgA antibodies in CVL were assessed by western blotting. At first recruitment of women with LSIL (100 cases), IL-10 mRNA and cytokine in HPV positive group (60 cases) was significantly higher than negative group (40 cases). IFN-γ and TNF-α mRNA level in both groups were comparable but their secretions in CVL were significantly increased in HPV negative group. After abrasion for 6 months in HPV-positive women, all mRNA and secreted cytokines were changed, but no significant difference was observed between cryotherapy and observation groups. When individuals were compared between first recruitment and after abrasion for 6 months, IFN-γ mRNA and anti-HPV16 L1 IgA antibodies were significantly increased in the cryotherapy group. The results suggest that modulation of local cervical immunities by abrasion might promote different effects in clearance of HPV-related cytological abnormalities." @default.
• W2100525080 created "2016-06-24" @default.
• W2100525080 creator A5017654796 @default.
• W2100525080 creator A5017825037 @default.
• W2100525080 creator A5048344126 @default.
• W2100525080 creator A5080442175 @default.
• W2100525080 creator A5088821017 @default.
• W2100525080 creator A5091813615 @default.
• W2100525080 date "2014-05-30" @default.
• W2100525080 modified "2023-10-15" @default.
• W2100525080 title "Local Cervical Immunity in Women with Low-grade Squamous Intraepithelial Lesions and Immune Responses After Abrasion" @default.
• W2100525080 cites W1963836825 @default.
• W2100525080 cites W1987816098 @default.
• W2100525080 cites W1992242242 @default.
• W2100525080 cites W2018524935 @default.
• W2100525080 cites W2045591762 @default.
• W2100525080 cites W2054643867 @default.
• W2100525080 cites W2055374705 @default.
• W2100525080 cites W2056083288 @default.
• W2100525080 cites W2076862423 @default.
• W2100525080 cites W2088924525 @default.
• W2100525080 cites W2090870297 @default.
• W2100525080 cites W2102235987 @default.
• W2100525080 cites W2103347596 @default.
• W2100525080 cites W2109250135 @default.
• W2100525080 cites W2110486727 @default.
• W2100525080 cites W2142836090 @default.
• W2100525080 cites W2143780505 @default.
• W2100525080 cites W2155336642 @default.
• W2100525080 cites W2159310692 @default.
• W2100525080 cites W2162318046 @default.
• W2100525080 doi "https://doi.org/10.7314/apjcp.2014.15.10.4197" @default.
• W2100525080 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24935370" @default.
• W2100525080 hasPublicationYear "2014" @default.
• W2100525080 type Work @default.
• W2100525080 sameAs 2100525080 @default.
• W2100525080 citedByCount "8" @default.
• W2100525080 countsByYear W21005250802016 @default.
• W2100525080 countsByYear W21005250802017 @default.
• W2100525080 countsByYear W21005250802018 @default.
• W2100525080 countsByYear W21005250802019 @default.
• W2100525080 countsByYear W21005250802020 @default.
• W2100525080 countsByYear W21005250802022 @default.
• W2100525080 crossrefType "journal-article" @default.
• W2100525080 hasAuthorship W2100525080A5017654796 @default.
• W2100525080 hasAuthorship W2100525080A5017825037 @default.
• W2100525080 hasAuthorship W2100525080A5048344126 @default.
• W2100525080 hasAuthorship W2100525080A5080442175 @default.
• W2100525080 hasAuthorship W2100525080A5088821017 @default.
• W2100525080 hasAuthorship W2100525080A5091813615 @default.
• W2100525080 hasBestOaLocation W21005250801 @default.
• W2100525080 hasConcept C121608353 @default.
• W2100525080 hasConcept C126322002 @default.
• W2100525080 hasConcept C141071460 @default.
• W2100525080 hasConcept C159654299 @default.
• W2100525080 hasConcept C203014093 @default.
• W2100525080 hasConcept C2775924586 @default.
• W2100525080 hasConcept C2777343196 @default.
• W2100525080 hasConcept C2777740455 @default.
• W2100525080 hasConcept C2778220009 @default.
• W2100525080 hasConcept C2778580637 @default.
• W2100525080 hasConcept C2778690821 @default.
• W2100525080 hasConcept C2779341262 @default.
• W2100525080 hasConcept C2780149145 @default.
• W2100525080 hasConcept C2994532551 @default.
• W2100525080 hasConcept C71924100 @default.
• W2100525080 hasConcept C8891405 @default.
• W2100525080 hasConceptScore W2100525080C121608353 @default.
• W2100525080 hasConceptScore W2100525080C126322002 @default.
• W2100525080 hasConceptScore W2100525080C141071460 @default.
• W2100525080 hasConceptScore W2100525080C159654299 @default.
• W2100525080 hasConceptScore W2100525080C203014093 @default.
• W2100525080 hasConceptScore W2100525080C2775924586 @default.
• W2100525080 hasConceptScore W2100525080C2777343196 @default.
• W2100525080 hasConceptScore W2100525080C2777740455 @default.
• W2100525080 hasConceptScore W2100525080C2778220009 @default.
• W2100525080 hasConceptScore W2100525080C2778580637 @default.
• W2100525080 hasConceptScore W2100525080C2778690821 @default.
• W2100525080 hasConceptScore W2100525080C2779341262 @default.
• W2100525080 hasConceptScore W2100525080C2780149145 @default.
• W2100525080 hasConceptScore W2100525080C2994532551 @default.
• W2100525080 hasConceptScore W2100525080C71924100 @default.
• W2100525080 hasConceptScore W2100525080C8891405 @default.
• W2100525080 hasIssue "10" @default.
• W2100525080 hasLocation W21005250801 @default.
• W2100525080 hasLocation W21005250802 @default.
• W2100525080 hasOpenAccess W2100525080 @default.
• W2100525080 hasPrimaryLocation W21005250801 @default.
• W2100525080 hasRelatedWork W147290333 @default.
• W2100525080 hasRelatedWork W2047496768 @default.
• W2100525080 hasRelatedWork W2066860562 @default.
• W2100525080 hasRelatedWork W2084443552 @default.
• W2100525080 hasRelatedWork W2133249944 @default.
• W2100525080 hasRelatedWork W2371548766 @default.
• W2100525080 hasRelatedWork W2372323723 @default.
• W2100525080 hasRelatedWork W2383766373 @default.
• W2100525080 hasRelatedWork W2418607614 @default.
• W2100525080 hasRelatedWork W3143946599 @default.

• next