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- W2100539870 abstract "We have studied a new approach to analyzing the genetic information and manipulating the three dimensional structure of human chromosomes by atomic force microscopy (AFM). A novel knife edge-shaped AFM probe device has been designed and fabricated on the basis of micromachining technology for the manipulation of double-stranded DNA and human chromosomes. We attempted to dissect double-stranded DNA and human chromosomes physically using the knife-edged probe under AFM operation. It was possible to dissect the chromosomes into finer and sharper parts compared with the conventional AFM probe." @default.
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- W2100539870 date "2005-08-24" @default.
- W2100539870 modified "2023-09-22" @default.
- W2100539870 title "A new design of knife edged-AFM probe for chromosome precision manipulating" @default.
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- W2100539870 doi "https://doi.org/10.1109/sensor.2005.1496382" @default.
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