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• W2100563229 abstract "Linkage disequilibrium (LD) is an association between genetic loci that is typically transient. Here, we identify a previously overlooked cause of stable LD that may be pervasive: sexual antagonism. This form of selection produces unequal allele frequencies in males and females each generation, which upon admixture at fertilization give rise to an excess of haplotypes that couple male-beneficial with male-beneficial and female-beneficial with female-beneficial alleles. Under sexual antagonism, LD is obtained for all recombination frequencies in the absence of epistasis. The extent of LD is highest at low recombination and for stronger selection. We provide a partition of the total LD into distinct components and compare our result for sexual antagonism with Li and Nei's model of LD owing to population subdivision. Given the frequent observation of sexually antagonistic selection in natural populations and the number of traits that are often involved, these results suggest a major contribution of sexual antagonism to genomic structure." @default.
• W2100563229 created "2016-06-24" @default.
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• W2100563229 date "2010-09-22" @default.
• W2100563229 modified "2023-10-18" @default.
• W2100563229 title "Stable linkage disequilibrium owing to sexual antagonism" @default.
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• W2100563229 doi "https://doi.org/10.1098/rspb.2010.1201" @default.
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