FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2100572021> ?p ?o ?g. }

• W2100572021 endingPage "8102" @default.
• W2100572021 startingPage "8093" @default.
• W2100572021 abstract "ABSTRACT Hydrostatic pressure in the range of 15 to 25 MPa was found to cause arrest of the cell cycle in G 1 phase in an exponentially growing culture of Saccharomyces cerevisiae , whereas a pressure of 50 MPa did not. We found that a plasmid carrying the TAT2 gene, which encodes a high-affinity tryptophan permease, enabled the cells to grow under conditions of pressure in the range of 15 to 25 MPa. Additionally, cells expressing the Tat2 protein at high levels became endowed with the ability to grow under low-temperature conditions at 10 or 15°C as well as at high pressure. Hydrostatic pressure significantly inhibited tryptophan uptake into the cells, and the Tat2 protein level was down-regulated by high pressure. The activation volume associated with tryptophan uptake was found to be a large positive value, 46.2 ± 3.85 ml/mol, indicating that there was a net volume increase in a rate-limiting step in tryptophan import. The results showing cell cycle arrest in G 1 phase and down-regulation of the Tat2 protein seem to be similar to those observed upon treatment of cells with the immunosuppressive drug rapamycin. Although rapamycin treatment elicited the rapid dephosphorylation of Npr1 and induction of Gap1 expression, hydrostatic pressure did not affect the phosphorylation state of Npr1 and it decreased the level of Gap1 protein, suggesting that the pressure-sensing pathway may be independent of Npr1 function. Here we describe high-pressure sensing in yeast in comparison with the TOR-signaling pathway and discuss an important factor involved in adaptation of organisms to high-pressure environments." @default.
• W2100572021 created "2016-06-24" @default.
• W2100572021 creator A5048509472 @default.
• W2100572021 creator A5077149436 @default.
• W2100572021 date "2000-11-01" @default.
• W2100572021 modified "2023-10-13" @default.
• W2100572021 title "Tryptophan Permease Gene <i>TAT2</i> Confers High-Pressure Growth in <i>Saccharomyces cerevisiae</i>" @default.
• W2100572021 cites W1507367785 @default.
• W2100572021 cites W1549158836 @default.
• W2100572021 cites W1588841090 @default.
• W2100572021 cites W1614347411 @default.
• W2100572021 cites W1953308090 @default.
• W2100572021 cites W1964138543 @default.
• W2100572021 cites W1965367429 @default.
• W2100572021 cites W1973782344 @default.
• W2100572021 cites W1984121313 @default.
• W2100572021 cites W1988938688 @default.
• W2100572021 cites W1990643576 @default.
• W2100572021 cites W1995039844 @default.
• W2100572021 cites W2001108068 @default.
• W2100572021 cites W2001158613 @default.
• W2100572021 cites W2002716861 @default.
• W2100572021 cites W2020455130 @default.
• W2100572021 cites W2026402396 @default.
• W2100572021 cites W2038125537 @default.
• W2100572021 cites W2038352464 @default.
• W2100572021 cites W2040810020 @default.
• W2100572021 cites W2046680363 @default.
• W2100572021 cites W2051410387 @default.
• W2100572021 cites W2064412858 @default.
• W2100572021 cites W2068413127 @default.
• W2100572021 cites W2073586734 @default.
• W2100572021 cites W2081118837 @default.
• W2100572021 cites W2087711181 @default.
• W2100572021 cites W2089367761 @default.
• W2100572021 cites W2089952439 @default.
• W2100572021 cites W2104828971 @default.
• W2100572021 cites W2118600791 @default.
• W2100572021 cites W2121018790 @default.
• W2100572021 cites W2122735072 @default.
• W2100572021 cites W2122883560 @default.
• W2100572021 cites W2123264979 @default.
• W2100572021 cites W2126415488 @default.
• W2100572021 cites W2131432246 @default.
• W2100572021 cites W2131742042 @default.
• W2100572021 cites W2134671651 @default.
• W2100572021 cites W2143282242 @default.
• W2100572021 cites W2143301340 @default.
• W2100572021 cites W2148162883 @default.
• W2100572021 cites W2161897058 @default.
• W2100572021 cites W2162829341 @default.
• W2100572021 cites W2163010202 @default.
• W2100572021 cites W2169333620 @default.
• W2100572021 cites W2308384344 @default.
• W2100572021 doi "https://doi.org/10.1128/mcb.20.21.8093-8102.2000" @default.
• W2100572021 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/86419" @default.
• W2100572021 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11027279" @default.
• W2100572021 hasPublicationYear "2000" @default.
• W2100572021 type Work @default.
• W2100572021 sameAs 2100572021 @default.
• W2100572021 citedByCount "146" @default.
• W2100572021 countsByYear W21005720212012 @default.
• W2100572021 countsByYear W21005720212013 @default.
• W2100572021 countsByYear W21005720212014 @default.
• W2100572021 countsByYear W21005720212015 @default.
• W2100572021 countsByYear W21005720212016 @default.
• W2100572021 countsByYear W21005720212017 @default.
• W2100572021 countsByYear W21005720212018 @default.
• W2100572021 countsByYear W21005720212019 @default.
• W2100572021 countsByYear W21005720212020 @default.
• W2100572021 countsByYear W21005720212021 @default.
• W2100572021 countsByYear W21005720212022 @default.
• W2100572021 countsByYear W21005720212023 @default.
• W2100572021 crossrefType "journal-article" @default.
• W2100572021 hasAuthorship W2100572021A5048509472 @default.
• W2100572021 hasAuthorship W2100572021A5077149436 @default.
• W2100572021 hasBestOaLocation W21005720211 @default.
• W2100572021 hasConcept C104317684 @default.
• W2100572021 hasConcept C149011108 @default.
• W2100572021 hasConcept C190114821 @default.
• W2100572021 hasConcept C2776706248 @default.
• W2100572021 hasConcept C2777576037 @default.
• W2100572021 hasConcept C515207424 @default.
• W2100572021 hasConcept C54355233 @default.
• W2100572021 hasConcept C55493867 @default.
• W2100572021 hasConcept C86803240 @default.
• W2100572021 hasConceptScore W2100572021C104317684 @default.
• W2100572021 hasConceptScore W2100572021C149011108 @default.
• W2100572021 hasConceptScore W2100572021C190114821 @default.
• W2100572021 hasConceptScore W2100572021C2776706248 @default.
• W2100572021 hasConceptScore W2100572021C2777576037 @default.
• W2100572021 hasConceptScore W2100572021C515207424 @default.
• W2100572021 hasConceptScore W2100572021C54355233 @default.
• W2100572021 hasConceptScore W2100572021C55493867 @default.
• W2100572021 hasConceptScore W2100572021C86803240 @default.
• W2100572021 hasIssue "21" @default.
• W2100572021 hasLocation W21005720211 @default.
• W2100572021 hasLocation W21005720212 @default.

• next