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- W2100611378 abstract "Yeast α and a cells transcribe distinct sets of genes involved in mating behavior, α-specific genes and a-specific genes, respectively. The α1 product of the α mating type locus (MATα) has been the only known activator of either set of genes; it is required for synthesis of RNA from the α-specific genes, one of which is the major α-factor gene. By screening for mutants that are no longer able to express this gene, we have identified the STE12 gene product as another positive regulator of the α-factor gene, α ste12 cells are also defective in RNA production from the other known α-specific genes. Moreover, a ste12 cells fail to produce wild-type levels of RNA from the a-specific genes. The STE12 gene product is therefore an activator of two sets of genes involved in yeast cell type specialization." @default.
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- W2100611378 date "1985-10-01" @default.
- W2100611378 modified "2023-10-15" @default.
- W2100611378 title "The yeast STE12 product is required for expression of two sets of cell-type-specific genes" @default.
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- W2100611378 doi "https://doi.org/10.1016/0092-8674(85)90288-0" @default.
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