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- W2100660268 abstract "INTRODUCTION .... . . . . . . .. . . . . . . . . . . . . . . . . . .. . . .... ... . . . . . . . . . . . . . . .. . . . . . . . . . . . . . . . .. . . . ... . . . . . . 271 HISTOR y . . . . . . ... . . ..... . . . . . . . . . . . . . . . . . . . . . . . .... ...... ... . . . . . . . . . . ...... . .. . . . . . . . . . . .. . . . . .... . . . . 272 BREAKTHROUG H PRODUC TS . . . . . . . . . . . . . . . . . ...... . . . . . . . . . . . ....... . . . . . . . . . . . . . . .. . . . . . . . . . 273 lmmunomodulators. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 273 Enzyme Inhibitors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 274 Receptor Antagonists . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 275 Inhibitors of Cellular Proliferation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 276 AGR ICULTUR AL PRODUCTS . . . . . . . . . .... .. ..... . .. . . . . . . . . . . . ..... .... . . . . . . . . . .. . . . . . . . . . . . . . 278 N EWLY R ECOGNIZED AC TIVITIES OF K NOWN COMPOUNDS . . . . . . .... . . . . . . . . . . . 280 CHEM IC ALLY MODIFIED M ICROB IAL PRODUCTS . . . . . . . . . . . . . . . . . . .... . . . . . . . . . . . . . . . 281 COMMON S TRUCTURAL THEMES . . . . . . . . . .... .. ... . .. . . . . . .. . . . .. . . . .. . . . . . .. . . . . 282 Macrolides . . . .. . .. .. .. . . . .. . . . . . . . . . . . . . . . . . . . . . . .. . ....... . . . . . . . . . . . . . . .... . . . . . . . . . . . . . . . . . . . . . . 282 Cyclic Peptides . . . . . . . . . . . . . . . ... . . . .. . . . . . . . . . . . . ... . . . . . . . . . .. . . . . . . . . . . . . . . . . . . . . . . .. . . . . . . . . . . . 283 RATION AL SCREENING . . . . . . . . . . . . . . . . . .. . . . . . . . . . . .... . . . . . . . . . . . . . . . . . . .... . . . . . . . . . . . . . . . . . . . 284 Assay Methods. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 284 Choice of Microorganisms . . .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 286 FUTURE TRENDS .... . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. . . . . . . ... . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 289" @default.
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- W2100660268 date "1990-10-01" @default.
- W2100660268 modified "2023-10-15" @default.
- W2100660268 title "BIOACTIVE MICROBIAL PRODUCTS: Focus upon Mechanism of Action" @default.
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