FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2100690809> ?p ?o ?g. }

• W2100690809 endingPage "712" @default.
• W2100690809 startingPage "704" @default.
• W2100690809 abstract "The masking of deleterious mutations by complementation and the reassortment of virus segments (virus sex) are expected to increase population genetic diversity among coinfecting viruses. Conversely, clonally reproducing or noncoinfecting virus populations may experience clonal interference where viral clones compete with one another, preventing selective sweeps. This dynamic reduces the efficiency of selection and increases the genetic diversity. To determine the relative influences of these forces on population genetic diversity, we evolved 6 populations of bacteriophage φ6 under conditions promoting or preventing coinfection. Following 300 generations, we isolated and partially sequenced 10 clones from each population. We found greater diversity among asexual populations than sexual populations. Moreover, sexual populations did not show greater relative fitnesses than asexual populations, implying that reduced genetic variation did not result from purifying selection. However, sexual populations were less genetically robust than asexual populations and likely more prone to the deleterious epistatic effects of mutations. As such, a neutral mutation on the asexually evolved (robust) background could be profoundly deleterious on the sexually evolved (brittle) background. This could facilitate sexual populations undergoing greater purifying selection to remove deleterious mutations, but this selection is not reflected by increases in average population fitness. Our results bolster a growing literature suggesting that RNA virus segmentation is probably not a mechanism that evolved because it provides a generalized benefit of sex." @default.
• W2100690809 created "2016-06-24" @default.
• W2100690809 creator A5007945304 @default.
• W2100690809 creator A5019444422 @default.
• W2100690809 creator A5040485140 @default.
• W2100690809 creator A5066152144 @default.
• W2100690809 creator A5091734816 @default.
• W2100690809 date "2013-07-04" @default.
• W2100690809 modified "2023-10-17" @default.
• W2100690809 title "Frequent Coinfection Reduces RNA Virus Population Genetic Diversity" @default.
• W2100690809 cites W1544060051 @default.
• W2100690809 cites W1578941079 @default.
• W2100690809 cites W1590937105 @default.
• W2100690809 cites W1760553141 @default.
• W2100690809 cites W1789840735 @default.
• W2100690809 cites W1795351263 @default.
• W2100690809 cites W1851737710 @default.
• W2100690809 cites W1904261486 @default.
• W2100690809 cites W1969060402 @default.
• W2100690809 cites W1971112779 @default.
• W2100690809 cites W1972848138 @default.
• W2100690809 cites W1988057380 @default.
• W2100690809 cites W1993418368 @default.
• W2100690809 cites W1997663263 @default.
• W2100690809 cites W2005999307 @default.
• W2100690809 cites W2006712471 @default.
• W2100690809 cites W2007280212 @default.
• W2100690809 cites W2014300152 @default.
• W2100690809 cites W2014496483 @default.
• W2100690809 cites W2018953152 @default.
• W2100690809 cites W2020939898 @default.
• W2100690809 cites W2021037732 @default.
• W2100690809 cites W2021443073 @default.
• W2100690809 cites W2023698809 @default.
• W2100690809 cites W2023925845 @default.
• W2100690809 cites W2024483403 @default.
• W2100690809 cites W2036857271 @default.
• W2100690809 cites W2042310235 @default.
• W2100690809 cites W2043037678 @default.
• W2100690809 cites W2053109557 @default.
• W2100690809 cites W2064052093 @default.
• W2100690809 cites W2068258718 @default.
• W2100690809 cites W2088451270 @default.
• W2100690809 cites W2088637708 @default.
• W2100690809 cites W2099212793 @default.
• W2100690809 cites W2106136193 @default.
• W2100690809 cites W2108240125 @default.
• W2100690809 cites W2119044344 @default.
• W2100690809 cites W2123563299 @default.
• W2100690809 cites W2124061807 @default.
• W2100690809 cites W2126280636 @default.
• W2100690809 cites W2130271218 @default.
• W2100690809 cites W2130333286 @default.
• W2100690809 cites W2130757930 @default.
• W2100690809 cites W2141631694 @default.
• W2100690809 cites W2144583160 @default.
• W2100690809 cites W2144802497 @default.
• W2100690809 cites W2146397496 @default.
• W2100690809 cites W2146442942 @default.
• W2100690809 cites W2146861035 @default.
• W2100690809 cites W2148734328 @default.
• W2100690809 cites W2158563479 @default.
• W2100690809 cites W2173451456 @default.
• W2100690809 cites W2314806880 @default.
• W2100690809 cites W4205371239 @default.
• W2100690809 cites W4248841475 @default.
• W2100690809 cites W4255086890 @default.
• W2100690809 doi "https://doi.org/10.1093/jhered/est038" @default.
• W2100690809 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23828608" @default.
• W2100690809 hasPublicationYear "2013" @default.
• W2100690809 type Work @default.
• W2100690809 sameAs 2100690809 @default.
• W2100690809 citedByCount "18" @default.
• W2100690809 countsByYear W21006908092014 @default.
• W2100690809 countsByYear W21006908092015 @default.
• W2100690809 countsByYear W21006908092016 @default.
• W2100690809 countsByYear W21006908092017 @default.
• W2100690809 countsByYear W21006908092018 @default.
• W2100690809 countsByYear W21006908092019 @default.
• W2100690809 countsByYear W21006908092020 @default.
• W2100690809 countsByYear W21006908092021 @default.
• W2100690809 countsByYear W21006908092022 @default.
• W2100690809 crossrefType "journal-article" @default.
• W2100690809 hasAuthorship W2100690809A5007945304 @default.
• W2100690809 hasAuthorship W2100690809A5019444422 @default.
• W2100690809 hasAuthorship W2100690809A5040485140 @default.
• W2100690809 hasAuthorship W2100690809A5066152144 @default.
• W2100690809 hasAuthorship W2100690809A5091734816 @default.
• W2100690809 hasBestOaLocation W21006908091 @default.
• W2100690809 hasConcept C104317684 @default.
• W2100690809 hasConcept C126831891 @default.
• W2100690809 hasConcept C141231307 @default.
• W2100690809 hasConcept C144024400 @default.
• W2100690809 hasConcept C149923435 @default.
• W2100690809 hasConcept C154945302 @default.
• W2100690809 hasConcept C2522874641 @default.
• W2100690809 hasConcept C2777813720 @default.
• W2100690809 hasConcept C2779356413 @default.

• next