FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2100703323> ?p ?o ?g. }

• W2100703323 endingPage "1224" @default.
• W2100703323 startingPage "1215" @default.
• W2100703323 abstract "Abstract BACKGROUND The clinical relevance of slightly increased circulating troponin concentrations in patients with stable coronary heart disease (CHD) several weeks after an acute event or CABG has not been fully evaluated. METHODS Baseline plasma concentrations of troponin T were measured with a high-sensitivity assay (hs-cTnT) (Roche Elecsys) in a cohort of 1050 CHD patients from 30 to 70 years of age. The prognostic value of hs-cTnT on a combined cardiovascular disease (CVD) end point after adjustment for covariates was determined with Cox proportional hazards modeling. RESULTS The median hs-cTnT concentration was 10.9 ng/L (interquartile range, 5.1–18.9 ng/L). Increased hs-cTnT concentrations were associated with an older age, history of hypertension and diabetes, more advanced coronary artery disease, and other CHD risk factors. Furthermore, hs-cTnT concentration was strongly correlated with N-terminal pro–B-type natriuretic peptide (NT-proBNP) and cystatin C (ρ = 0.61, and ρ = 0.32, respectively; both P values &lt;0.0001). During a median follow-up of 8.1 years, 150 patients (14.3%) experienced a secondary CVD event. In a multivariate model, hs-cTnT was associated with a hazard ratio (HR) for secondary events of 2.83 (95% CI, 1.68–4.79) when the extreme quartiles were compared. Further adjustment for cystatin C, NT-proBNP, and C-reactive protein attenuated this association only slightly (HR, 2.27; 95% CI, 1.31–3.95); P for trend &lt; 0.002). ROC curve analysis of a clinical model that added hs-cTnT to a baseline model showed nonsignificant improvement in the area under the curve (0.69 vs 0.67), whereas the net reclassification improvement was 17.2% (P = 0.029). CONCLUSIONS Slightly increased hs-cTnT concentrations in stable CHD patients are associated with several cardiovascular disorders and predict long-term CVD events." @default.
• W2100703323 created "2016-06-24" @default.
• W2100703323 creator A5008640592 @default.
• W2100703323 creator A5028480812 @default.
• W2100703323 creator A5034322720 @default.
• W2100703323 creator A5048101127 @default.
• W2100703323 creator A5077206620 @default.
• W2100703323 creator A5085471666 @default.
• W2100703323 date "2012-08-01" @default.
• W2100703323 modified "2023-09-23" @default.
• W2100703323 title "Cardiac Troponin T Measured by a High-Sensitivity Assay Predicts Recurrent Cardiovascular Events in Stable Coronary Heart Disease Patients with 8-Year Follow-up" @default.
• W2100703323 cites W1526964507 @default.
• W2100703323 cites W1572665035 @default.
• W2100703323 cites W17701363 @default.
• W2100703323 cites W1974718993 @default.
• W2100703323 cites W1991198324 @default.
• W2100703323 cites W2015491565 @default.
• W2100703323 cites W2018700684 @default.
• W2100703323 cites W2020840201 @default.
• W2100703323 cites W2065942755 @default.
• W2100703323 cites W2066554944 @default.
• W2100703323 cites W2094872638 @default.
• W2100703323 cites W2098002403 @default.
• W2100703323 cites W2098105324 @default.
• W2100703323 cites W2098332177 @default.
• W2100703323 cites W2104867019 @default.
• W2100703323 cites W2105378753 @default.
• W2100703323 cites W2112316706 @default.
• W2100703323 cites W2113883406 @default.
• W2100703323 cites W2121236256 @default.
• W2100703323 cites W2126384336 @default.
• W2100703323 cites W2126830306 @default.
• W2100703323 cites W2132346721 @default.
• W2100703323 cites W2157184686 @default.
• W2100703323 cites W2169735148 @default.
• W2100703323 cites W2327567334 @default.
• W2100703323 doi "https://doi.org/10.1373/clinchem.2012.183319" @default.
• W2100703323 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22634379" @default.
• W2100703323 hasPublicationYear "2012" @default.
• W2100703323 type Work @default.
• W2100703323 sameAs 2100703323 @default.
• W2100703323 citedByCount "51" @default.
• W2100703323 countsByYear W21007033232012 @default.
• W2100703323 countsByYear W21007033232013 @default.
• W2100703323 countsByYear W21007033232014 @default.
• W2100703323 countsByYear W21007033232015 @default.
• W2100703323 countsByYear W21007033232016 @default.
• W2100703323 countsByYear W21007033232017 @default.
• W2100703323 countsByYear W21007033232018 @default.
• W2100703323 countsByYear W21007033232019 @default.
• W2100703323 countsByYear W21007033232020 @default.
• W2100703323 countsByYear W21007033232021 @default.
• W2100703323 countsByYear W21007033232022 @default.
• W2100703323 countsByYear W21007033232023 @default.
• W2100703323 crossrefType "journal-article" @default.
• W2100703323 hasAuthorship W2100703323A5008640592 @default.
• W2100703323 hasAuthorship W2100703323A5028480812 @default.
• W2100703323 hasAuthorship W2100703323A5034322720 @default.
• W2100703323 hasAuthorship W2100703323A5048101127 @default.
• W2100703323 hasAuthorship W2100703323A5077206620 @default.
• W2100703323 hasAuthorship W2100703323A5085471666 @default.
• W2100703323 hasBestOaLocation W21007033231 @default.
• W2100703323 hasConcept C119060515 @default.
• W2100703323 hasConcept C126322002 @default.
• W2100703323 hasConcept C144469398 @default.
• W2100703323 hasConcept C159641895 @default.
• W2100703323 hasConcept C164705383 @default.
• W2100703323 hasConcept C207103383 @default.
• W2100703323 hasConcept C2775915353 @default.
• W2100703323 hasConcept C2778198053 @default.
• W2100703323 hasConcept C2778213512 @default.
• W2100703323 hasConcept C2779548226 @default.
• W2100703323 hasConcept C36036425 @default.
• W2100703323 hasConcept C44249647 @default.
• W2100703323 hasConcept C500558357 @default.
• W2100703323 hasConcept C50382708 @default.
• W2100703323 hasConcept C71924100 @default.
• W2100703323 hasConcept C8880881 @default.
• W2100703323 hasConceptScore W2100703323C119060515 @default.
• W2100703323 hasConceptScore W2100703323C126322002 @default.
• W2100703323 hasConceptScore W2100703323C144469398 @default.
• W2100703323 hasConceptScore W2100703323C159641895 @default.
• W2100703323 hasConceptScore W2100703323C164705383 @default.
• W2100703323 hasConceptScore W2100703323C207103383 @default.
• W2100703323 hasConceptScore W2100703323C2775915353 @default.
• W2100703323 hasConceptScore W2100703323C2778198053 @default.
• W2100703323 hasConceptScore W2100703323C2778213512 @default.
• W2100703323 hasConceptScore W2100703323C2779548226 @default.
• W2100703323 hasConceptScore W2100703323C36036425 @default.
• W2100703323 hasConceptScore W2100703323C44249647 @default.
• W2100703323 hasConceptScore W2100703323C500558357 @default.
• W2100703323 hasConceptScore W2100703323C50382708 @default.
• W2100703323 hasConceptScore W2100703323C71924100 @default.
• W2100703323 hasConceptScore W2100703323C8880881 @default.
• W2100703323 hasIssue "8" @default.
• W2100703323 hasLocation W21007033231 @default.
• W2100703323 hasLocation W21007033232 @default.
• W2100703323 hasOpenAccess W2100703323 @default.

• next