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- W2100808422 abstract "Abstract: We have generated a human monoclonal cytotoxic IgMlD antibody (TrJ3) that reacted specifically with all lymphoblastoid B-cell lines expressing HLA-B44(12) and B45(12). TrJ3 hybridoma supernatant was suitable for HLA-B IZ typing of freshly isolated blood mononuclear cells. Analysis of available amino acid sequences of HLA-B molecules indicated that the al domain does not contain the TrJ3 serological epitope. Since HLA-B44 is associated with a unique serine residue at position 167 that points towards the peptide binding groove, we propose that S167 of the α2 domain helix is a critical part of the TrJ3 epitope." @default.
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- W2100808422 date "1992-05-01" @default.
- W2100808422 modified "2023-10-12" @default.
- W2100808422 title "A cytotoxic monoclonal human hybridoma antibody (TrJ3) against HLA-B44(12) and -B45(12)" @default.
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- W2100808422 doi "https://doi.org/10.1111/j.1399-0039.1992.tb01944.x" @default.
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