FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2100937870> ?p ?o ?g. }

• W2100937870 abstract "Members of the proteolipid protein family, including the four-transmembrane glycoprotein M6a, are involved in neuronal plasticity in mammals. Results from our group previously demonstrated that M6, the only proteolipid protein expressed in Drosophila, localizes to the cell membrane in follicle cells. M6 loss triggers female sterility, which suggests a role for M6 in follicular cell remodeling. These results were the basis of the present study, which focused on the function and requirements of M6 in the fly nervous system. The present study identified two novel, tissue-regulated M6 isoforms with variable N- and C- termini, and showed that M6 is the functional fly ortholog of Gpm6a. In the adult brain, the protein was localized to several neuropils, such as the optic lobe, the central complex, and the mushroom bodies. Interestingly, although reduced M6 levels triggered a mild rough-eye phenotype, hypomorphic M6 mutants exhibited a defective response to light. Based on its ability to induce filopodium formation we propose that M6 is key in cell remodeling processes underlying visual system function. These results bring further insight into the role of M6/M6a in biological processes involving neuronal plasticity and behavior in flies and mammals." @default.
• W2100937870 created "2016-06-24" @default.
• W2100937870 creator A5009127701 @default.
• W2100937870 creator A5019107214 @default.
• W2100937870 creator A5020670732 @default.
• W2100937870 creator A5024976971 @default.
• W2100937870 creator A5037105094 @default.
• W2100937870 creator A5081814176 @default.
• W2100937870 date "2012-07-04" @default.
• W2100937870 modified "2023-10-08" @default.
• W2100937870 title "A role for the membrane protein M6 in the Drosophila visual system" @default.
• W2100937870 cites W1552956347 @default.
• W2100937870 cites W1564923928 @default.
• W2100937870 cites W1759354465 @default.
• W2100937870 cites W1801668047 @default.
• W2100937870 cites W1894754493 @default.
• W2100937870 cites W1969757253 @default.
• W2100937870 cites W1973027447 @default.
• W2100937870 cites W1983769291 @default.
• W2100937870 cites W1985297803 @default.
• W2100937870 cites W1986885740 @default.
• W2100937870 cites W1994261045 @default.
• W2100937870 cites W1999252644 @default.
• W2100937870 cites W2013754064 @default.
• W2100937870 cites W2014084841 @default.
• W2100937870 cites W2015157239 @default.
• W2100937870 cites W2019110153 @default.
• W2100937870 cites W2023441938 @default.
• W2100937870 cites W2023692012 @default.
• W2100937870 cites W2024892377 @default.
• W2100937870 cites W2036012822 @default.
• W2100937870 cites W2049389808 @default.
• W2100937870 cites W2050638312 @default.
• W2100937870 cites W2055752262 @default.
• W2100937870 cites W2071113961 @default.
• W2100937870 cites W2073365737 @default.
• W2100937870 cites W2073638458 @default.
• W2100937870 cites W2077411919 @default.
• W2100937870 cites W2077776663 @default.
• W2100937870 cites W2086623210 @default.
• W2100937870 cites W2091713244 @default.
• W2100937870 cites W2094369068 @default.
• W2100937870 cites W2100590938 @default.
• W2100937870 cites W2103046819 @default.
• W2100937870 cites W2108244474 @default.
• W2100937870 cites W2110863368 @default.
• W2100937870 cites W2111752062 @default.
• W2100937870 cites W2123347941 @default.
• W2100937870 cites W2159817218 @default.
• W2100937870 cites W2171779714 @default.
• W2100937870 cites W4321319567 @default.
• W2100937870 doi "https://doi.org/10.1186/1471-2202-13-78" @default.
• W2100937870 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3438117" @default.
• W2100937870 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22762289" @default.
• W2100937870 hasPublicationYear "2012" @default.
• W2100937870 type Work @default.
• W2100937870 sameAs 2100937870 @default.
• W2100937870 citedByCount "9" @default.
• W2100937870 countsByYear W21009378702014 @default.
• W2100937870 countsByYear W21009378702015 @default.
• W2100937870 countsByYear W21009378702018 @default.
• W2100937870 countsByYear W21009378702020 @default.
• W2100937870 countsByYear W21009378702022 @default.
• W2100937870 crossrefType "journal-article" @default.
• W2100937870 hasAuthorship W2100937870A5009127701 @default.
• W2100937870 hasAuthorship W2100937870A5019107214 @default.
• W2100937870 hasAuthorship W2100937870A5020670732 @default.
• W2100937870 hasAuthorship W2100937870A5024976971 @default.
• W2100937870 hasAuthorship W2100937870A5037105094 @default.
• W2100937870 hasAuthorship W2100937870A5081814176 @default.
• W2100937870 hasBestOaLocation W21009378701 @default.
• W2100937870 hasConcept C104317684 @default.
• W2100937870 hasConcept C144647389 @default.
• W2100937870 hasConcept C169760540 @default.
• W2100937870 hasConcept C170493617 @default.
• W2100937870 hasConcept C24530287 @default.
• W2100937870 hasConcept C2776038537 @default.
• W2100937870 hasConcept C2778609137 @default.
• W2100937870 hasConcept C2780104201 @default.
• W2100937870 hasConcept C2780876595 @default.
• W2100937870 hasConcept C41625074 @default.
• W2100937870 hasConcept C529278444 @default.
• W2100937870 hasConcept C54355233 @default.
• W2100937870 hasConcept C7821365 @default.
• W2100937870 hasConcept C86803240 @default.
• W2100937870 hasConcept C95444343 @default.
• W2100937870 hasConceptScore W2100937870C104317684 @default.
• W2100937870 hasConceptScore W2100937870C144647389 @default.
• W2100937870 hasConceptScore W2100937870C169760540 @default.
• W2100937870 hasConceptScore W2100937870C170493617 @default.
• W2100937870 hasConceptScore W2100937870C24530287 @default.
• W2100937870 hasConceptScore W2100937870C2776038537 @default.
• W2100937870 hasConceptScore W2100937870C2778609137 @default.
• W2100937870 hasConceptScore W2100937870C2780104201 @default.
• W2100937870 hasConceptScore W2100937870C2780876595 @default.
• W2100937870 hasConceptScore W2100937870C41625074 @default.
• W2100937870 hasConceptScore W2100937870C529278444 @default.
• W2100937870 hasConceptScore W2100937870C54355233 @default.
• W2100937870 hasConceptScore W2100937870C7821365 @default.
• W2100937870 hasConceptScore W2100937870C86803240 @default.

• next