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• W2100966474 endingPage "1361" @default.
• W2100966474 startingPage "1361" @default.
• W2100966474 abstract "Neurologic disorders are frequently a result of inappropriate electrical and/or chemical signaling of neurons and glia. Ultimate remediation would necessitate reprogramming these signals. Historically, correcting neuronal and glial signaling is accomplished via drug therapy/administration, although they frequently fail to effectively and fully treat the underlying disorder. Developments in basic research have produced several new classes of potential therapeutics to directly and precisely control neuron activity at the single-cell level. We review one such technology, Designer Receptors Exclusively Activated by Designer Drugs, and suggest its potential as a powerful tool for augmenting neuronal and glial signaling and activity for basic and translational applications." @default.
• W2100966474 created "2016-06-24" @default.
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• W2100966474 date "2015-11-01" @default.
• W2100966474 modified "2023-10-10" @default.
• W2100966474 title "Chemogenetics—A Transformational and Translational Platform" @default.
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• W2100966474 doi "https://doi.org/10.1001/jamaneurol.2015.1921" @default.
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